Reduced levels of Su(var)3-9 but not Su(var)2-5 (HP1) counteract the effects on chromatin structure and viability in loss-of-function mutants of the JIL-1 histone H3S10 kinase.
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Linker histone H1 is essential for Drosophila development, the establishment of pericentric heterochromatin, and a normal polytene chromosome structurePhosphorylation of SU(VAR)3-9 by the chromosomal kinase JIL-1.Genome-wide analysis of regulation of gene expression and H3K9me2 distribution by JIL-1 kinase mediated histone H3S10 phosphorylation in DrosophilaHistone H3S10 phosphorylation by the JIL-1 kinase in pericentric heterochromatin and on the fourth chromosome creates a composite H3S10phK9me2 epigenetic mark.Global analysis of the relationship between JIL-1 kinase and transcription.JIL-1 and Su(var)3-7 interact genetically and counteract each other's effect on position-effect variegation in DrosophilaEnrichment of HP1a on Drosophila chromosome 4 genes creates an alternate chromatin structure critical for regulation in this heterochromatic domain.A balance between euchromatic (JIL-1) and heterochromatic [SU(var)2-5 and SU(var)3-9] factors regulates position-effect variegation in Drosophila.The epigenetic H3S10 phosphorylation mark is required for counteracting heterochromatic spreading and gene silencing in Drosophila melanogasterHistone H3 phosphorylation - a versatile chromatin modification for different occasions.RNA polymerase II-mediated transcription at active loci does not require histone H3S10 phosphorylation in Drosophila.The effect of JIL-1 on position-effect variegation is proportional to the total amount of heterochromatin in the genome.upSET, the Drosophila homologue of SET3, Is Required for Viability and the Proper Balance of Active and Repressive Chromatin Marks.H2Av facilitates H3S10 phosphorylation but is not required for heat shock-induced chromatin decondensation or transcriptional elongation.H3S10 phosphorylation by the JIL-1 kinase regulates H3K9 dimethylation and gene expression at the white locus in Drosophila.
P2860
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P2860
Reduced levels of Su(var)3-9 but not Su(var)2-5 (HP1) counteract the effects on chromatin structure and viability in loss-of-function mutants of the JIL-1 histone H3S10 kinase.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Reduced levels of Su(var)3-9 b ...... he JIL-1 histone H3S10 kinase.
@ast
Reduced levels of Su(var)3-9 b ...... he JIL-1 histone H3S10 kinase.
@en
type
label
Reduced levels of Su(var)3-9 b ...... he JIL-1 histone H3S10 kinase.
@ast
Reduced levels of Su(var)3-9 b ...... he JIL-1 histone H3S10 kinase.
@en
prefLabel
Reduced levels of Su(var)3-9 b ...... he JIL-1 histone H3S10 kinase.
@ast
Reduced levels of Su(var)3-9 b ...... he JIL-1 histone H3S10 kinase.
@en
P2093
P2860
P1433
P1476
Reduced levels of Su(var)3-9 b ...... the JIL-1 histone H3S10 kinase
@en
P2093
Jack Girton
Jørgen Johansen
Kristen M Johansen
P2860
P356
10.1534/GENETICS.107.075143
P407
P577
2007-07-29T00:00:00Z