about
A specialized nucleosome has a "point" to make.JIL-1 kinase, a member of the male-specific lethal (MSL) complex, is necessary for proper dosage compensation of eye pigmentation in Drosophila.Centromere and kinetochore gene misexpression predicts cancer patient survival and response to radiotherapy and chemotherapy.Genetic and phenotypic analysis of alleles of the Drosophila chromosomal JIL-1 kinase reveals a functional requirement at multiple developmental stages.Frodos found: Behold the CENP-a "Ring" bearersAssembly of Drosophila centromeric nucleosomes requires CID dimerizationReduced levels of Su(var)3-9 but not Su(var)2-5 (HP1) counteract the effects on chromatin structure and viability in loss-of-function mutants of the JIL-1 histone H3S10 kinase.The COOH-terminal domain of the JIL-1 histone H3S10 kinase interacts with histone H3 and is required for correct targeting to chromatinGenome-wide analysis reveals a cell cycle-dependent mechanism controlling centromere propagation.Megator, an essential coiled-coil protein that localizes to the putative spindle matrix during mitosis in Drosophila.The JIL-1 tandem kinase mediates histone H3 phosphorylation and is required for maintenance of chromatin structure in Drosophila.The JIL-1 kinase interacts with lamin Dm0 and regulates nuclear lamina morphology of Drosophila nurse cells.
P50
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Weiguo Zhang
@ast
Weiguo Zhang
@en
Weiguo Zhang
@es
Weiguo Zhang
@nl
type
label
Weiguo Zhang
@ast
Weiguo Zhang
@en
Weiguo Zhang
@es
Weiguo Zhang
@nl
prefLabel
Weiguo Zhang
@ast
Weiguo Zhang
@en
Weiguo Zhang
@es
Weiguo Zhang
@nl
P106
P31
P496
0000-0002-3045-0569