Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease
about
Alpha1-antichymotrypsin/Alzheimer's peptide Abeta(1-42) complex perturbs lipid metabolism and activates transcription factors PPARgamma and NFkappaB in human neuroblastoma (Kelly) cellsDynein light chain LC8 negatively regulates NF-kappaB through the redox-dependent interaction with IkappaBalphaCyclooxygenase-2 is a neuronal target gene of NF-kappaBNF-kappaB Signaling Pathways in Neurological Inflammation: A Mini ReviewInnate Immune Response in Brain, NF-Kappa B Signaling and CystatinsNF-KappaB in Long-Term Memory and Structural Plasticity in the Adult Mammalian BrainElusive roles for reactive astrocytes in neurodegenerative diseasesMechanisms of islet amyloidosis toxicity in type 2 diabetesParallels between major depressive disorder and Alzheimer's disease: role of oxidative stress and genetic vulnerabilityHsp70.1 and related lysosomal factors for necrotic neuronal deathNeuronal Gene Targets of NF-κB and Their Dysregulation in Alzheimer's DiseaseAlzheimer's disease and type 2 diabetes via chronic inflammatory mechanismsInflammation and Alzheimer's diseasePDZ domain-dependent suppression of NF-kappaB/p65-induced Abeta42 production by a neuron-specific X11-like proteinNF-kappaB pathway: a target for preventing beta-amyloid (Abeta)-induced neuronal damage and Abeta42 productionLipopolysaccharide from Rhodobacter sphaeroides Attenuates Microglia-Mediated Inflammation and Phagocytosis and Directs Regulatory T Cell ResponseHippocampal apoptosis in major depression is a minor event and absent from subareas at risk for glucocorticoid overexposureOridonin attenuates Aβ1-42-induced neuroinflammation and inhibits NF-κB pathwayOpposing roles for NF-kappa B/Rel factors p65 and c-Rel in the modulation of neuron survival elicited by glutamate and interleukin-1betaHydrogen peroxide induces the death of astrocytes through the down-regulation of the constitutive nuclear factor-kappaB activitySortilin-related receptor with A-type repeats (SORLA) affects the amyloid precursor protein-dependent stimulation of ERK signaling and adult neurogenesisAlcohol exposure after mild focal traumatic brain injury impairs neurological recovery and exacerbates localized neuroinflammation.From calcium to NF-kappa B signaling pathways in neurons.Retrograde transport of transcription factor NF-kappa B in living neurons.The modular systems biology approach to investigate the control of apoptosis in Alzheimer's disease neurodegeneration.Neuroadaptations in human chronic alcoholics: dysregulation of the NF-kappaB system.Accumulation of phosphorylated I kappaB alpha and activated IKK in nodes of Ranvier.The oxysterol 27-hydroxycholesterol increases β-amyloid and oxidative stress in retinal pigment epithelial cells.Glia Maturation Factor and Mitochondrial Uncoupling Proteins 2 and 4 Expression in the Temporal Cortex of Alzheimer's Disease BrainAssociation analysis of rare variants near the APOE region with CSF and neuroimaging biomarkers of Alzheimer's disease.TAp63 is a transcriptional target of NF-kappaB.Anti-inflammatory drugs: a hope for Alzheimer's disease?Negative regulation of NF-κB activity by brain-specific TRIpartite Motif protein 9.Mechanisms of neurodegeneration and regeneration in alcoholismLow K+ promotes NF-kappaB/DNA binding in neuronal apoptosis induced by K+ loss.Interleukin-1 signaling pathway as a therapeutic target in transthyretin amyloidosis.From theory to therapy: implications from an in vitro model of ramified microglia.Interaction of transactive response DNA binding protein 43 with nuclear factor κB in mild cognitive impairment with episodic memory deficits.Tauroursodeoxycholic acid prevents amyloid-beta peptide-induced neuronal death via a phosphatidylinositol 3-kinase-dependent signaling pathway.Adiponectin is protective against oxidative stress induced cytotoxicity in amyloid-beta neurotoxicity
P2860
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P2860
Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Transcription factor NF-kappaB ...... atients with Alzheimer disease
@ast
Transcription factor NF-kappaB ...... atients with Alzheimer disease
@en
type
label
Transcription factor NF-kappaB ...... atients with Alzheimer disease
@ast
Transcription factor NF-kappaB ...... atients with Alzheimer disease
@en
prefLabel
Transcription factor NF-kappaB ...... atients with Alzheimer disease
@ast
Transcription factor NF-kappaB ...... atients with Alzheimer disease
@en
P2093
P2860
P356
P1476
Transcription factor NF-kappaB ...... atients with Alzheimer disease
@en
P2093
Baeuerle PA
Kaltschmidt B
Kaltschmidt C
P2860
P304
P356
10.1073/PNAS.94.6.2642
P407
P577
1997-03-01T00:00:00Z