Structure of an intermediate conformer of the spindle checkpoint protein Mad2

Structure of an intermediate conformer of the spindle checkpoint protein Mad2

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http://www.wikidata.org/entity/Q36056858
The multifaceted roles of the HORMA domain in cellular signalingLessons from making the Structural Classification of Proteins (SCOP) and their implications for protein structure modellingMAD2γ, a novel MAD2 isoform, reduces mitotic arrest and is associated with resistance in testicular germ cell tumors.Emerging links among Chromosome Instability (CIN), cancer, and aging.A sequential multi-target Mps1 phosphorylation cascade promotes spindle checkpoint signaling.Docking of CDK1 with antibiotic drugs revealed novel therapeutic value in breast ductal cancer in situ.Conformational dynamics of the Hop1 HORMA domain reveal a common mechanism with the spindle checkpoint protein Mad2.Molecular Mechanisms of Spindle Assembly Checkpoint Activation and Silencing.Mechanistic insight into TRIP13-catalyzed Mad2 structural transition and spindle checkpoint silencing.Direct interactions of mitotic arrest deficient 1 (MAD1) domains with each other and MAD2 conformers are required for mitotic checkpoint signaling.Dynamic feature of mitotic arrest deficient 2-like protein 2 (MAD2L2) and structural basis for its interaction with chromosome alignment-maintaining phosphoprotein (CAMP).Peptide inhibitors of the anaphase promoting-complex that cause sensitivity to microtubule poison.MAD1: Kinetochore Receptors and Catalytic Mechanisms.TRIP13 and APC15 drive mitotic exit by turnover of interphase- and unattached kinetochore-produced MCCMechanism for remodelling of the cell cycle checkpoint protein MAD2 by the ATPase TRIP13
P2860

Structure of an intermediate conformer of the spindle checkpoint protein Mad2

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http://www.wikidata.org/entity/Q36056858
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2015 nî lūn-bûn
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2015年の論文
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2015年論文
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Structure of an intermediate conformer of the spindle checkpoint protein Mad2
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Structure of an intermediate conformer of the spindle checkpoint protein Mad2
@en
type
label
Structure of an intermediate conformer of the spindle checkpoint protein Mad2
@ast
Structure of an intermediate conformer of the spindle checkpoint protein Mad2
@en
prefLabel
Structure of an intermediate conformer of the spindle checkpoint protein Mad2
@ast
Structure of an intermediate conformer of the spindle checkpoint protein Mad2
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Structure of an intermediate conformer of the spindle checkpoint protein Mad2
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932