TCN 201 selectively blocks GluN2A-containing NMDARs in a GluN1 co-agonist dependent but non-competitive manner
about
Novel NMDA receptor modulators: an updateNMDA receptor modulators: an updated patent review (2013-2014)The Concise Guide to PHARMACOLOGY 2013/14: ligand-gated ion channels.β-arrestin-2 regulates NMDA receptor function in spinal lamina II neurons and duration of persistent pain.PAR1-activated astrocytes in the nucleus of the solitary tract stimulate adjacent neurons via NMDA receptors.Sensitivity of N-methyl-D-aspartate receptor-mediated excitatory postsynaptic potentials and synaptic plasticity to TCN 201 and TCN 213 in rat hippocampal slices.MPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA Receptors Containing the GluN2A Subunit.NMDA Receptors Containing the GluN2D Subunit Control Neuronal Function in the Subthalamic Nucleus.NR2A- and NR2B-containing NMDA receptors in the prelimbic medial prefrontal cortex differentially mediate trace, delay, and contextual fear conditioning.STEP activation by Gαq coupled GPCRs opposes Src regulation of NMDA receptors containing the GluN2A subunit.NR2A-Containing NMDARs in the Prefrontal Cortex Are Required for Working Memory and Associated with Age-Related Cognitive Decline.Influence of GluN2 subunit identity on NMDA receptor function.GluN2D-Containing N-methyl-d-Aspartate Receptors Mediate Synaptic Transmission in Hippocampal Interneurons and Regulate Interneuron Activity.Characterization of physiological phenotypes of dentate gyrus synapses of PDZ1/2 domain-deficient PSD-95-knockin mice.Presynaptic N-Methyl-d-aspartate (NMDA) Receptor Activity Is Increased Through Protein Kinase C in Paclitaxel-induced Neuropathic PainStructural Basis for Negative Allosteric Modulation of GluN2A-Containing NMDA Receptors.Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex.Pedunculopontine glutamatergic neurons control spike patterning in substantia nigra dopaminergic neurons.Extrasynaptic glutamate release through cystine/glutamate antiporter contributes to ischemic damagePresynaptic NR2A-Containing NMDARs Are Required for LTD between the Amygdala and the Perirhinal Cortex: A Potential Mechanism for the Emotional Modulation of Memory?(1,2,3).NMDA Receptors in the Central Nervous System.The Structure-Activity Relationship of a Tetrahydroisoquinoline Class of N-Methyl-d-Aspartate Receptor Modulators that Potentiates GluN2B-Containing N-Methyl-d-Aspartate Receptors.NMDA Receptor GluN2 Subtypes Control Epileptiform Events in the Hippocampus.Pharmacological characterisation of ligand- and voltage-gated ion channels expressed in human iPSC-derived forebrain neurons.Disease-associated missense mutations in GluN2B subunit alter NMDA receptor ligand binding and ion channel properties.Inhibition of α5 subunit-containing GABAA receptors facilitated spinal nociceptive transmission and plasticity.
P2860
Q26849614-90D4D3C2-3828-4AFA-9F8C-7E6190C33C0EQ26997407-F0C59311-1B34-45F1-969B-B76404A0002EQ30486732-B33702C5-F4FB-454D-A0A3-7632F8BAAFF1Q33814944-A94F846F-2EBE-4C0C-8E97-A836F6511E30Q34946408-0E3ADB44-1A48-4356-9352-6205DF1A6B47Q34946701-06416C9E-7A18-4E7D-8889-DD3BC36524BEQ35909724-AB2F7A23-104E-442F-8E4D-6D2B5DAE5A2CQ36339205-31820E41-FD4D-4D87-B917-53EAD3EFA2CEQ36914507-2DCF41F6-4B6C-4AD9-9D69-AFABAF513678Q37421633-81FA76C9-CF3F-497F-99A5-43DA69AE21A8Q37504950-20E5E13A-C58A-4998-9AFB-CF8EAEB16AAEQ38078685-C8D874AF-1360-4F9B-B790-325FE3B423C6Q39393906-5CAF75F5-A440-4327-BFE2-F2383A8EBCCAQ40192516-953E72CC-5CC3-498A-BB36-43B06F59CBFFQ41049504-2C3B8E28-1F3C-4C74-8EE3-CDD04A98E02DQ41159277-F2E90B9E-4DEB-4122-ABD3-2E4AE4AC5D90Q42222806-BC517525-0B8F-4F72-8054-05D540862540Q42378714-FE1B7D00-4DDA-4EB1-82E8-E8AE7D398B37Q42592261-99DD9FFD-81CE-4F66-8A02-6C96AAA8EC7FQ42707602-AF63797D-2989-475B-8653-16EA4EF840E0Q48029905-698D9D4C-FD80-42F3-8A3C-5BDA424F2D4BQ48320720-B8A29050-5918-4DA0-9BE1-F5291EAE580FQ50041763-72E1C4FD-851B-4401-97F4-287FE79C7661Q50344665-CCAC4E31-48E2-481C-8EA8-F5B3FECF25C4Q50418409-50953AE6-1CB9-40D8-B6AB-36AB3E5B8286Q53666755-7FBB29B0-8984-4068-8EC4-9401432C007F
P2860
TCN 201 selectively blocks GluN2A-containing NMDARs in a GluN1 co-agonist dependent but non-competitive manner
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
TCN 201 selectively blocks Glu ...... ent but non-competitive manner
@ast
TCN 201 selectively blocks Glu ...... ent but non-competitive manner
@en
type
label
TCN 201 selectively blocks Glu ...... ent but non-competitive manner
@ast
TCN 201 selectively blocks Glu ...... ent but non-competitive manner
@en
prefLabel
TCN 201 selectively blocks Glu ...... ent but non-competitive manner
@ast
TCN 201 selectively blocks Glu ...... ent but non-competitive manner
@en
P2093
P2860
P1433
P1476
TCN 201 selectively blocks Glu ...... ent but non-competitive manner
@en
P2093
D J A Wyllie
G E Hardingham
L J Macdonald
M R Livesey
P2860
P304
P356
10.1016/J.NEUROPHARM.2012.04.027
P577
2012-05-01T00:00:00Z