Thymocyte responsiveness to endogenous glucocorticoids is required for immunological fitness - Wikidata - awgldk - TriplyDB

Thymocyte responsiveness to endogenous glucocorticoids is required for immunological fitness

Thymocyte responsiveness to endogenous glucocorticoids is required for immunological fitness

http://www.wikidata.org/entity/Q36068343

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Scavenger receptor BI and high-density lipoprotein regulate thymocyte apoptosis in sepsis Live cell imaging unveils multiple domain requirements for in vivo dimerization of the glucocorticoid receptor.Suppression of Dendritic Cell-Derived IL-12 by Endogenous Glucocorticoids Is Protective in LPS-Induced Sepsis.CD8 lineage-specific regulation of interleukin-7 receptor expression by the transcriptional repressor Gfi1.Differential regulation of HMG-CoA reductase and Insig-1 by enzymes of the ubiquitin-proteasome system.Thymus: the next (re)generation.CD4+ T cells are trigger and target of the glucocorticoid response that prevents lethal immunopathology in toxoplasma infection Systemic toxoplasma infection triggers a long-term defect in the generation and function of naive T lymphocytes.Glucocorticoid Receptor Accelerates, but Is Dispensable for, Adipogenesis Leukotriene B4 receptor 1 is differentially expressed on peripheral T cells of steroid-sensitive and -resistant asthmatics.Development of novel treatment strategies for inflammatory diseases-similarities and divergence between glucocorticoids and GILZ.Glucocorticoids and Cancer.Suppression of B-cell development genes is key to glucocorticoid efficacy in treatment of acute lymphoblastic leukemia.Molecular Actions of Glucocorticoids in Cartilage and Bone During Health, Disease, and Steroid Therapy.Antenatal endogenous and exogenous glucocorticoids and their impact on immune ontogeny and long-term immunity.New Insights in Glucocorticoid Receptor Signaling-More Than Just a Ligand-Binding Receptor B-cell identity as a metabolic barrier against malignant transformation.T-cell autonomous death induced by regeneration of inert glucocorticoid metabolites.NCoR1 restrains thymic negative selection by repressing Bim expression to spare thymocytes undergoing positive selection.Effect of prenatal steroid treatment on the developing immune system.Prenatal Administration of Betamethasone Causes Changes in the T Cell Receptor Repertoire Influencing Development of Autoimmunity.Host resistance to endotoxic shock requires the neuroendocrine regulation of group 1 innate lymphoid cells.Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation.Cutting Edge: De Novo Glucocorticoid Synthesis by Thymic Epithelial Cells Regulates Antigen-Specific Thymocyte Selection.Glucocorticoid Signaling in Health and Disease: Insights From Tissue-Specific GR Knockout Mice.Glucocorticoid Receptor Signaling Is Not Required for In Vivo Adipogenesis.Tuberculosis, the Disrupted Immune-Endocrine Response and the Potential Thymic Repercussion As a Contributing Factor to Disease Physiopathology.Interactions Between the Neuroendocrine System and T Lymphocytes in Diabetes.Glucocorticoid Receptor and Adipocyte Biology

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P2860

Thymocyte responsiveness to endogenous glucocorticoids is required for immunological fitness

http://www.wikidata.org/entity/Q36068343

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

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2012年论文

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2012年论文

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name

Thymocyte responsiveness to en ...... ired for immunological fitness

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Thymocyte responsiveness to en ...... ired for immunological fitness

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Thymocyte responsiveness to en ...... ired for immunological fitness

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Thymocyte responsiveness to en ...... ired for immunological fitness

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Thymocyte responsiveness to en ...... ired for immunological fitness

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Journal of Clinical Investigation

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Thymocyte responsiveness to en ...... ired for immunological fitness

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Jonathan D Ashwell

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João P Monteiro

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Paul R Mittelstadt

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P2860

Protein-protein interactions and transcriptional antagonism between the subfamily of NGFI-B/Nur77 orphan nuclear receptors and glucocorticoid receptor

Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection

Themis, a T cell-specific protein important for late thymocyte development

Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

The molecular basis of TCR germline bias for MHC is surprisingly simple

Signaling by the kinase MINK is essential in the negative selection of autoreactive thymocytes

Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

How TCRs bind MHCs, peptides, and coreceptors

GRKO mice express an aberrant dexamethasone-binding glucocorticoid receptor, but are profoundly glucocorticoid resistant.

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2384-2394

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scholarly article

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10.1172/JCI63067

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7

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122

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2012-06-01T00:00:00Z

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22653054

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3386828

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