A functional telomerase RNA swap in vivo reveals the importance of nontemplate RNA domains
about
Polymerization defects within human telomerase are distinct from telomerase RNA and TEP1 bindingA human-Tetrahymena pseudoknot chimeric telomerase RNA reconstitutes a nonprocessive enzyme in vitro that is defective in telomere elongationRNA-dependent activation of primer RNA production by influenza virus polymerase: different regions of the same protein subunit constitute the two required RNA-binding sites.The MRT-1 nuclease is required for DNA crosslink repair and telomerase activity in vivo in Caenorhabditis elegansFlexible positioning of the telomerase-associated nuclease leads to preferential elimination of nontelomeric DNA.Roles for RNA in telomerase nucleotide and repeat addition processivity.Telomerase recognizes its template by using an adjacent RNA motif.Telomere maintenance mechanisms as a target for drug development.Determinants in mammalian telomerase RNA that mediate enzyme processivity and cross-species incompatibility.Mutational analysis of the Tetrahymena telomerase RNA: identification of residues affecting telomerase activity in vitroTelomerase RNA function in recombinant Tetrahymena telomerase.Specific telomerase RNA residues distant from the template are essential for telomerase function.Telomerase in kinetoplastid parasitic protozoa.Expression of mouse telomerase catalytic subunit in embryos and adult tissues.Functional analysis of conserved residues in the putative "finger" domain of telomerase reverse transcriptase.Interference footprinting analysis of telomerase elongation complexes.Functional regions of human telomerase reverse transcriptase and human telomerase RNA required for telomerase activity and RNA-protein interactions.Three telomerases with completely non-telomeric template replacements are catalytically active.Human telomerase catalyzes nucleolytic primer cleavage.A human telomerase-associated nuclease.Protein binding to expanded telomere repeats in Tetrahymena thermophila.Processive utilization of the human telomerase template: lack of a requirement for template switching.
P2860
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P2860
A functional telomerase RNA swap in vivo reveals the importance of nontemplate RNA domains
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
A functional telomerase RNA sw ...... nce of nontemplate RNA domains
@ast
A functional telomerase RNA sw ...... nce of nontemplate RNA domains
@en
type
label
A functional telomerase RNA sw ...... nce of nontemplate RNA domains
@ast
A functional telomerase RNA sw ...... nce of nontemplate RNA domains
@en
prefLabel
A functional telomerase RNA sw ...... nce of nontemplate RNA domains
@ast
A functional telomerase RNA sw ...... nce of nontemplate RNA domains
@en
P2860
P356
P1476
A functional telomerase RNA sw ...... nce of nontemplate RNA domains
@en
P2093
A Bhattacharyya
P2860
P304
P356
10.1073/PNAS.94.7.2823
P407
P577
1997-04-01T00:00:00Z