Progressive atrioventricular conduction defects and heart failure in mice expressing a mutant Csx/Nkx2.5 homeoprotein
about
MURC, a muscle-restricted coiled-coil protein that modulates the Rho/ROCK pathway, induces cardiac dysfunction and conduction disturbanceIdentification of cardiac-specific myosin light chain kinaseCardiac disease and arrhythmogenesis: Mechanistic insights from mouse modelsThe cardiac conduction systemComplex SUMO-1 regulation of cardiac transcription factor Nkx2-5Perinatal loss of Nkx2-5 results in rapid conduction and contraction defectsNKX2-5, a modifier of skeletal muscle pathology due to RNA toxicity.RNA toxicity in myotonic muscular dystrophy induces NKX2-5 expression.Transient early embryonic expression of Nkx2-5 mutations linked to congenital heart defects in human causes heart defects in Xenopus laevis.Ablation of Nkx2-5 at mid-embryonic stage results in premature lethality and cardiac malformationReciprocal myocardial-endocardial interactions pattern the delay in atrioventricular junction conduction.Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling.Gene expression profiling of the aging mouse cardiac myocytes.Development of electrocardiogram intervals during growth of FVB/N neonate mice.Genetic causes of human heart failure.Expression of sumoylation deficient Nkx2.5 mutant in Nkx2.5 haploinsufficient mice leads to congenital heart defects.The App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a Down syndrome mouse model.Activation of Notch signaling pathway precedes heart regeneration in zebrafish.Coronary arteriogenesis and differentiation of periarterial Purkinje fibers in the chick heart: is there a link?The role of transcription factors in atrial fibrillationElectrophysiological phenotyping in genetically engineered mice.Transcriptional regulation of the murine Connexin40 promoter by cardiac factors Nkx2-5, GATA4 and Tbx5.A decade of discoveries in cardiac biology.Functional imaging of the embryonic pacemaking and cardiac conduction system over the past 150 years: technologies to overcome the challenges.Myocardial ischemia, reperfusion, and infarction in chronically instrumented, intact, conscious, and unrestrained miceCharacterization of embryonic cardiac pacemaker and atrioventricular conduction physiology in Xenopus laevis using noninvasive imaging.Prolongation of atrio-ventricular node conduction in a rabbit model of ischaemic cardiomyopathy: Role of fibrosis and connexin remodelling.Differentiation of cardiac Purkinje fibers requires precise spatiotemporal regulation of Nkx2-5 expression.Functional characterization of a novel mutation in NKX2-5 associated with congenital heart disease and adult-onset cardiomyopathy.Compound loss of muscleblind-like function in myotonic dystrophy.Transcriptional networks regulating the costamere, sarcomere, and other cytoskeletal structures in striated muscle.Cardiac electrophysiology in mice: a matter of size.Multilayered regulation of cardiac ion channels.Trafficking highways to the intercalated disc: new insights unlocking the specificity of connexin 43 localization.Heart failure in congenital heart disease: the role of genes and hemodynamics.A mouse model of human congenital heart disease: high incidence of diverse cardiac anomalies and ventricular noncompaction produced by heterozygous Nkx2-5 homeodomain missense mutation.Development and Function of the Cardiac Conduction System in Health and Disease.Transcriptional activator DOT1L putatively regulates human embryonic stem cell differentiation into the cardiac lineage.Functional dissection of sequence-specific NKX2-5 DNA binding domain mutations associated with human heart septation defects using a yeast-based system.Deletion of Nkx2-5 in trabecular myocardium reveals the developmental origins of pathological heterogeneity associated with ventricular non-compaction cardiomyopathy
P2860
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P2860
Progressive atrioventricular conduction defects and heart failure in mice expressing a mutant Csx/Nkx2.5 homeoprotein
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Progressive atrioventricular c ...... mutant Csx/Nkx2.5 homeoprotein
@ast
Progressive atrioventricular c ...... mutant Csx/Nkx2.5 homeoprotein
@en
type
label
Progressive atrioventricular c ...... mutant Csx/Nkx2.5 homeoprotein
@ast
Progressive atrioventricular c ...... mutant Csx/Nkx2.5 homeoprotein
@en
prefLabel
Progressive atrioventricular c ...... mutant Csx/Nkx2.5 homeoprotein
@ast
Progressive atrioventricular c ...... mutant Csx/Nkx2.5 homeoprotein
@en
P2093
P2860
P356
P1476
Progressive atrioventricular c ...... mutant Csx/Nkx2.5 homeoprotein
@en
P2093
C T Maguire
H Kasahara
H Wakimoto
K L Converso
P2860
P304
P356
10.1172/JCI12694
P407
P577
2001-07-01T00:00:00Z