The effect of a novel VMAT2 inhibitor, GZ-793A, on methamphetamine reward in rats.
about
SLC18: Vesicular neurotransmitter transporters for monoamines and acetylcholineThe effect of VMAT2 inhibitor GZ-793A on the reinstatement of methamphetamine-seeking in ratsThe vesicular monoamine transporter-2: an important pharmacological target for the discovery of novel therapeutics to treat methamphetamine abuse.Environmental enrichment reduces methamphetamine cue-induced reinstatement but does not alter methamphetamine reward or VMAT2 function.Novel N-1,2-dihydroxypropyl analogs of lobelane inhibit vesicular monoamine transporter-2 function and methamphetamine-evoked dopamine release.Vesicular monoamine transporter 2 and the acute and long-term response to 3,4-(±)-methylenedioxymethamphetamine.Preclinical Efficacy of Novel Vesicular Monoamine Transporter 2 Inhibitors as Antagonists of d-Methamphetamine Self-Administration in Rats.Effects of VMAT2 inhibitors lobeline and GZ-793A on methamphetamine-induced changes in dopamine release, metabolism and synthesis in vivoGZ-793A, a lobelane analog, interacts with the vesicular monoamine transporter-2 to inhibit the effect of methamphetamineImportance of Substrate-Coupled Proton Antiport by the Vesicular Monoamine Transporter in the Actions of Amphetamines in Drosophila Brain.Exploring the effect of N-substitution in nor-lobelane on the interaction with VMAT2: discovery of a potential clinical candidate for treatment of methamphetamine abuse.Lobelane analogues containing 4-hydroxy and 4-(2-fluoroethoxy) aromatic substituents: Potent and selective inhibitors of [(3)H]dopamine uptake at the vesicular monoamine transporter-2.Quinolyl analogues of norlobelane: novel potent inhibitors of [(3)H]dihydrotetrabenazine binding and [(3)H]dopamine uptake at the vesicular monoamine transporter-2.Oral administration of GZ-793A, a VMAT2 inhibitor, decreases methamphetamine self-administration in rats.Pyrrolidine analogs of GZ-793A: synthesis and evaluation as inhibitors of the vesicular monoamine transporter-2 (VMAT2).Varenicline and GZ-793A differentially decrease methamphetamine self-administration under a multiple schedule of reinforcement in rats.
P2860
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P2860
The effect of a novel VMAT2 inhibitor, GZ-793A, on methamphetamine reward in rats.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The effect of a novel VMAT2 inhibitor, GZ-793A, on methamphetamine reward in rats.
@ast
The effect of a novel VMAT2 inhibitor, GZ-793A, on methamphetamine reward in rats.
@en
type
label
The effect of a novel VMAT2 inhibitor, GZ-793A, on methamphetamine reward in rats.
@ast
The effect of a novel VMAT2 inhibitor, GZ-793A, on methamphetamine reward in rats.
@en
prefLabel
The effect of a novel VMAT2 inhibitor, GZ-793A, on methamphetamine reward in rats.
@ast
The effect of a novel VMAT2 inhibitor, GZ-793A, on methamphetamine reward in rats.
@en
P2093
P2860
P1433
P1476
The effect of a novel VMAT2 inhibitor, GZ-793A, on methamphetamine reward in rats.
@en
P2093
Emily D Denehy
Guangrong Zheng
Joshua S Beckmann
Linda P Dwoskin
Michael T Bardo
Peter A Crooks
P2860
P2888
P304
P356
10.1007/S00213-011-2488-9
P577
2011-09-21T00:00:00Z