Novel N-1,2-dihydroxypropyl analogs of lobelane inhibit vesicular monoamine transporter-2 function and methamphetamine-evoked dopamine release.
about
The effect of VMAT2 inhibitor GZ-793A on the reinstatement of methamphetamine-seeking in ratsThe vesicular monoamine transporter-2: an important pharmacological target for the discovery of novel therapeutics to treat methamphetamine abuse.New fluorescent substrate enables quantitative and high-throughput examination of vesicular monoamine transporter 2 (VMAT2)The effect of a novel VMAT2 inhibitor, GZ-793A, on methamphetamine reward in rats.Synthesis and in vitro evaluation of water-soluble 1,4-diphenethylpiperazine analogs as novel inhibitors of the vesicular monoamine transporter-2Preclinical Efficacy of Novel Vesicular Monoamine Transporter 2 Inhibitors as Antagonists of d-Methamphetamine Self-Administration in Rats.Effects of VMAT2 inhibitors lobeline and GZ-793A on methamphetamine-induced changes in dopamine release, metabolism and synthesis in vivoGZ-793A, a lobelane analog, interacts with the vesicular monoamine transporter-2 to inhibit the effect of methamphetamineImportance of Substrate-Coupled Proton Antiport by the Vesicular Monoamine Transporter in the Actions of Amphetamines in Drosophila Brain.Exploring the effect of N-substitution in nor-lobelane on the interaction with VMAT2: discovery of a potential clinical candidate for treatment of methamphetamine abuse.Lobelane analogues containing 4-hydroxy and 4-(2-fluoroethoxy) aromatic substituents: Potent and selective inhibitors of [(3)H]dopamine uptake at the vesicular monoamine transporter-2.Quinolyl analogues of norlobelane: novel potent inhibitors of [(3)H]dihydrotetrabenazine binding and [(3)H]dopamine uptake at the vesicular monoamine transporter-2.Oral administration of GZ-793A, a VMAT2 inhibitor, decreases methamphetamine self-administration in rats.Pyrrolidine analogs of GZ-793A: synthesis and evaluation as inhibitors of the vesicular monoamine transporter-2 (VMAT2).Varenicline and GZ-793A differentially decrease methamphetamine self-administration under a multiple schedule of reinforcement in rats.
P2860
Q28267531-275818F9-633B-439C-B29C-4BC2198717C8Q33854736-F448D4E0-0215-479E-9E56-5C82A37A53FAQ34823681-B0A7D44C-7813-4FCA-AB1E-A091AC260FC1Q36079830-C0BFBD3C-2AA3-4393-A8B0-DCEFE3DE45DCQ36103932-F8237EC9-CE7D-44AF-99DB-D9AFE65568CAQ37068964-79DBE6BA-6F99-4A52-BCE9-31A57B2B7116Q37227997-C8C3C7BC-8B9A-47EE-9EDA-E645F7202181Q37292517-D74F4362-FB1C-4154-B224-17C1727AE54EQ37619367-42E70488-A4D7-4DFB-9C02-A695356C35FAQ42098885-EF8E28CB-C352-495B-84D4-28008E343922Q42373565-9DADB162-07B0-4739-9A3D-6EC40FC168B5Q42682103-381F454A-0BD3-48E8-A45A-B40A4072BD17Q42864716-27BA6D7E-D0EE-434D-9C9B-BA8F72C1E94EQ43070321-FFF41DB4-95D6-4517-9F86-ACE880D2B9D9Q50235992-BB9552D2-3B6E-40ED-A98B-3A3EBBE91C36
P2860
Novel N-1,2-dihydroxypropyl analogs of lobelane inhibit vesicular monoamine transporter-2 function and methamphetamine-evoked dopamine release.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Novel N-1,2-dihydroxypropyl an ...... amine-evoked dopamine release.
@ast
Novel N-1,2-dihydroxypropyl an ...... amine-evoked dopamine release.
@en
Novel N-1,2-dihydroxypropyl an ...... amine-evoked dopamine release.
@nl
type
label
Novel N-1,2-dihydroxypropyl an ...... amine-evoked dopamine release.
@ast
Novel N-1,2-dihydroxypropyl an ...... amine-evoked dopamine release.
@en
Novel N-1,2-dihydroxypropyl an ...... amine-evoked dopamine release.
@nl
prefLabel
Novel N-1,2-dihydroxypropyl an ...... amine-evoked dopamine release.
@ast
Novel N-1,2-dihydroxypropyl an ...... amine-evoked dopamine release.
@en
Novel N-1,2-dihydroxypropyl an ...... amine-evoked dopamine release.
@nl
P2093
P2860
P356
P1476
Novel N-1,2-dihydroxypropyl an ...... amine-evoked dopamine release.
@en
P2093
David B Horton
Guangrong Zheng
Kiran B Siripurapu
Linda P Dwoskin
Peter A Crooks
P2860
P304
P356
10.1124/JPET.111.184770
P407
P577
2011-07-21T00:00:00Z