Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies. - Wikidata - awgldk - TriplyDB

Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies.

Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies.

http://www.wikidata.org/entity/Q36084984

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Nucleic Acid sensors and type I interferon production in systemic lupus erythematosus Neutrophil biology: an update Neutrophils: Between host defence, immune modulation, and tissue injury Does antigen masking by ubiquitin chains protect from the development of autoimmune diseases?An integrated peptide-antigen microarray on plasmonic gold films for sensitive human antibody profiling Competence-independent activity of pneumococcal EndA [corrected] mediates degradation of extracellular dna and nets and is important for virulence Immune recognition of citrullinated epitopes.Neutrophil extracellular traps: is immunity the second function of chromatin?Low-density granulocytes: a distinct class of neutrophils in systemic autoimmunity In vitro induction of NETosis: Comprehensive live imaging comparison and systematic review Identification of autoreactive B cells with labeled nucleosomes Lupus and proliferative nephritis are PAD4 independent in murine models.Neutrophil extracellular traps induce endothelial dysfunction in systemic lupus erythematosus through the activation of matrix metalloproteinase-2 NETs: the missing link between cell death and systemic autoimmune diseases?Potential of epigenetic therapies in non-cancerous conditions.Whole blood gene expression profiles in insulin resistant Latinos with the metabolic syndrome.Escherichia coli and Candida albicans induced macrophage extracellular trap-like structures with limited microbicidal activity.Neutrophil Extracellular Traps Identification in Tegumentary Lesions of Patients with Paracoccidioidomycosis and Different Patterns of NETs Generation In Vitro.Bicyclic-Capped Histone Deacetylase 6 Inhibitors with Improved Activity in a Model of Axonal Charcot-Marie-Tooth Disease Characterization of Autoantigens Targeted by Anti-Citrullinated Protein Antibodies In Vivo: Prominent Role for Epitopes Derived from Histone 4 Proteins.Neutrophil extracellular traps: double-edged swords of innate immunity.Potential role of peptidylarginine deiminase enzymes and protein citrullination in cancer pathogenesis.Autoantibodies against mono- and tri-methylated lysine display similar but also distinctive characteristics.A NET Outcome.Epigenetics in systemic lupus erythematosus Neutrophil extracellular trap-associated protein activation of the NLRP3 inflammasome is enhanced in lupus macrophages Identification of macrophage extracellular trap-like structures in mammary gland adipose tissue: a preliminary study.HMGB1 promotes neutrophil extracellular trap formation through interactions with Toll-like receptor 4 Development of Th17-Associated Interstitial Kidney Inflammation in Lupus-Prone Mice Lacking the Gene Encoding STAT-1.Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus Multiplex giant magnetoresistive biosensor microarrays identify interferon-associated autoantibodies in systemic lupus erythematosus MicroRNAs implicated in the immunopathogenesis of lupus nephritis.Alterations in nuclear structure promote lupus autoimmunity in a mouse model.Role of neutrophils in systemic autoimmune diseases Breaking immunological tolerance in systemic lupus erythematosus.B Cell Tolerance to Deiminated Histones in BALB/c, C57BL/6, and Autoimmune-Prone Mouse Strains.Apoptosis and NET formation in the pathogenesis of SLE.Proteins derived from neutrophil extracellular traps may serve as self-antigens and mediate organ damage in autoimmune diseases.Perspectives on epigenetic-based immune intervention for rheumatic diseases.Autoantigens: novel forms and presentation to the immune system.

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Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies.

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Ash A Alizadeh

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Chih Long Liu

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Emily C Gillespie

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Gil Mandelbaum

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Jacob M Rosenberg

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Stephanie Tangsombatvisit

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P2860

Cytokine-associated neutrophil extracellular traps and antinuclear antibodies in Plasmodium falciparum infected children under six years of age

Neutrophil extracellular traps contain calprotectin, a cytosolic protein complex involved in host defense against Candida albicans

Translating the Histone Code

Human autoimmune sera as molecular probes for the identification of an autoantigen kinase signaling pathway

Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

Significance analysis of microarrays applied to the ionizing radiation response

Cluster analysis and display of genome-wide expression patterns

Neutrophil extracellular traps kill bacteria

Histone acetylation in chromatin structure and transcription

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