CNS-specific therapy for ongoing EAE by silencing IL-17 pathway in astrocytes
about
Oligodendrocyte, Astrocyte, and Microglia Crosstalk in Myelin Development, Damage, and RepairWhat we know and do not know about the cannabinoid receptor 2 (CB2)Control of autoimmune CNS inflammation by astrocytesRole of high-mobility group box 1 in methamphetamine-induced activation and migration of astrocytesInvolvement of sigma-1 receptor in astrocyte activation induced by methamphetamine via up-regulation of its own expressionIncreased interleukin-17 in the cerebrospinal fluid in sporadic Creutzfeldt-Jakob disease: a case-control study of rapidly progressive dementiaAct1 mediates IL-17-induced EAE pathogenesis selectively in NG2+ glial cellsRegulation of astrocyte activation by glycolipids drives chronic CNS inflammation.Inhibitory effect of IL-17 on neural stem cell proliferation and neural cell differentiation.Silencing IFN-γ binding/signaling in astrocytes versus microglia leads to opposite effects on central nervous system autoimmunity.Origins and significance of astrogliosis in the multiple sclerosis model, MOG peptide EAEType I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor.Anti-IL-17A treatment reduces clinical score and VCAM-1 expression detected by in vivo magnetic resonance imaging in chronic relapsing EAE ABH miceIL-10-dependent Tr1 cells attenuate astrocyte activation and ameliorate chronic central nervous system inflammationAstrocytic Acid-Sensing Ion Channel 1a Contributes to the Development of Chronic EpileptogenesisNeurotrophin 3 transduction augments remyelinating and immunomodulatory capacity of neural stem cellsAntisense gene silencing: therapy for neurodegenerative disorders?Treatment of experimental autoimmune encephalomyelitis by codelivery of disease associated Peptide and dexamethasone in acetalated dextran microparticlesCytokine control of inflammation and repair in the pathology of multiple sclerosis.The role of IL-17 in CNS diseases.Celastrol Attenuates Multiple Sclerosis and Optic Neuritis in an Experimental Autoimmune Encephalomyelitis Model.Activity of secukinumab, an anti-IL-17A antibody, on brain lesions in RRMS: results from a randomized, proof-of-concept study.CXCR4 receptor overexpression in mesenchymal stem cells facilitates treatment of acute lung injury in rats.Effectors of Th1 and Th17 cells act on astrocytes and augment their neuroinflammatory properties.Astrocytes play a key role in EAE pathophysiology by orchestrating in the CNS the inflammatory response of resident and peripheral immune cells and by suppressing remyelination.CFHR1-Modified Neural Stem Cells Ameliorated Brain Injury in a Mouse Model of Neuromyelitis Optica Spectrum Disorders.Circular RNA HIPK2 regulates astrocyte activation via cooperation of autophagy and ER stress by targeting MIR124-2HG.IL-17A induces MIP-1α expression in primary astrocytes via Src/MAPK/PI3K/NF-kB pathways: implications for multiple sclerosis.
P2860
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P2860
CNS-specific therapy for ongoing EAE by silencing IL-17 pathway in astrocytes
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
CNS-specific therapy for ongoing EAE by silencing IL-17 pathway in astrocytes
@ast
CNS-specific therapy for ongoing EAE by silencing IL-17 pathway in astrocytes
@en
type
label
CNS-specific therapy for ongoing EAE by silencing IL-17 pathway in astrocytes
@ast
CNS-specific therapy for ongoing EAE by silencing IL-17 pathway in astrocytes
@en
prefLabel
CNS-specific therapy for ongoing EAE by silencing IL-17 pathway in astrocytes
@ast
CNS-specific therapy for ongoing EAE by silencing IL-17 pathway in astrocytes
@en
P2093
P2860
P356
P1433
P1476
CNS-specific therapy for ongoing EAE by silencing IL-17 pathway in astrocytes
@en
P2093
Abdolmohamad Rostami
Bogoljub Ciric
Guang-Xian Zhang
Xiaoli Ding
Yaping Yan
P2860
P304
P356
10.1038/MT.2012.12
P50
P577
2012-03-20T00:00:00Z