Simultaneous treatment of human bronchial epithelial cells with serine and cysteine protease inhibitors prevents severe acute respiratory syndrome coronavirus entry.
about
TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike proteinIdentification of a broad-spectrum antiviral small molecule against severe acute respiratory syndrome coronavirus and Ebola, Hendra, and Nipah viruses by using a novel high-throughput screening assayGlycan shield and epitope masking of a coronavirus spike protein observed by cryo-electron microscopyCoronaviruses and the human airway: a universal system for virus-host interaction studiesEbola virus and severe acute respiratory syndrome coronavirus display late cell entry kinetics: evidence that transport to NPC1+ endolysosomes is a rate-defining stepProteolytic activation of the SARS-coronavirus spike protein: cutting enzymes at the cutting edge of antiviral research.Inhibition of proprotein convertases abrogates processing of the middle eastern respiratory syndrome coronavirus spike protein in infected cells but does not reduce viral infectivity.DESC1 and MSPL activate influenza A viruses and emerging coronaviruses for host cell entry.Non-human primate orthologues of TMPRSS2 cleave and activate the influenza virus hemagglutinin.Protease inhibitors targeting coronavirus and filovirus entryCathepsin W Is Required for Escape of Influenza A Virus from Late Endosomes.The spike protein of the emerging betacoronavirus EMC uses a novel coronavirus receptor for entry, can be activated by TMPRSS2, and is targeted by neutralizing antibodies.TMPRSS2 is an activating protease for respiratory parainfluenza viruses.Middle East respiratory syndrome coronavirus infection mediated by the transmembrane serine protease TMPRSS2.Clinical Isolates of Human Coronavirus 229E Bypass the Endosome for Cell Entry.Cell-based antiviral screening against coronaviruses: developing virus-specific and broad-spectrum inhibitorsIdentification and characterization of a proteolytically primed form of the murine coronavirus spike proteins after fusion with the target cell.TMPRSS2 activates the human coronavirus 229E for cathepsin-independent host cell entry and is expressed in viral target cells in the respiratory epithelium.Identification of the first synthetic inhibitors of the type II transmembrane serine protease TMPRSS2 suitable for inhibition of influenza virus activation.Neurovirulent Murine Coronavirus JHM.SD Uses Cellular Zinc Metalloproteases for Virus Entry and Cell-Cell Fusion.Formation of fibroblastic reticular network in the brain after infection with neurovirulent murine coronavirus.Coronavirus and influenza virus proteolytic priming takes place in tetraspanin-enriched membrane microdomainsMice lacking α1,3-fucosyltransferase 9 exhibit modulation of in vivo immune responses against pathogens.Middle East Respiratory Syndrome and Severe Acute Respiratory Syndrome: Current Therapeutic Options and Potential Targets for Novel Therapies.
P2860
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P2860
Simultaneous treatment of human bronchial epithelial cells with serine and cysteine protease inhibitors prevents severe acute respiratory syndrome coronavirus entry.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Simultaneous treatment of huma ...... ry syndrome coronavirus entry.
@ast
Simultaneous treatment of huma ...... ry syndrome coronavirus entry.
@en
type
label
Simultaneous treatment of huma ...... ry syndrome coronavirus entry.
@ast
Simultaneous treatment of huma ...... ry syndrome coronavirus entry.
@en
prefLabel
Simultaneous treatment of huma ...... ry syndrome coronavirus entry.
@ast
Simultaneous treatment of huma ...... ry syndrome coronavirus entry.
@en
P2093
P2860
P356
P1433
P1476
Simultaneous treatment of huma ...... ry syndrome coronavirus entry.
@en
P2093
Fumihiro Taguchi
Kazuya Shirato
Miyuki Kawase
Shutoku Matsuyama
P2860
P304
P356
10.1128/JVI.00094-12
P407
P577
2012-04-11T00:00:00Z