Middle East respiratory syndrome coronavirus infection mediated by the transmembrane serine protease TMPRSS2.
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Identification of a broad-spectrum antiviral small molecule against severe acute respiratory syndrome coronavirus and Ebola, Hendra, and Nipah viruses by using a novel high-throughput screening assayMiddle East respiratory syndrome: obstacles and prospects for vaccine developmentStructure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitorFusion of Enveloped Viruses in Endosomes.A camel-derived MERS-CoV with a variant spike protein cleavage site and distinct fusion activation propertiesMERS-CoV spike protein: a key target for antivirals.A review of treatment modalities for Middle East Respiratory Syndrome.Abelson Kinase Inhibitors Are Potent Inhibitors of Severe Acute Respiratory Syndrome Coronavirus and Middle East Respiratory Syndrome Coronavirus Fusion.Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice.Inhibition of proprotein convertases abrogates processing of the middle eastern respiratory syndrome coronavirus spike protein in infected cells but does not reduce viral infectivity.DESC1 and MSPL activate influenza A viruses and emerging coronaviruses for host cell entry.Identification of TMPRSS2 as a Susceptibility Gene for Severe 2009 Pandemic A(H1N1) Influenza and A(H7N9) Influenza.The host protease TMPRSS2 plays a major role in in vivo replication of emerging H7N9 and seasonal influenza viruses.TMPRSS2 and MSPL Facilitate Trypsin-Independent Porcine Epidemic Diarrhea Virus Replication in Vero Cells.Structure, Function, and Evolution of Coronavirus Spike Proteins.Detection of Middle East respiratory syndrome coronavirus using reverse transcription loop-mediated isothermal amplification (RT-LAMP).Receptor usage and cell entry of bat coronavirus HKU4 provide insight into bat-to-human transmission of MERS coronavirus.Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein.Middle East respiratory syndrome coronavirus: another zoonotic betacoronavirus causing SARS-like diseaseSimian hemorrhagic fever virus cell entry is dependent on CD163 and uses a clathrin-mediated endocytosis-like pathwayHost cell proteases: Critical determinants of coronavirus tropism and pathogenesisThe Glycoproteins of All Filovirus Species Use the Same Host Factors for Entry into Bat and Human Cells but Entry Efficiency Is Species Dependent.Respiratory protease/antiprotease balance determines susceptibility to viral infection and can be modified by nutritional antioxidantsMiddle East respiratory syndrome coronavirus shows poor replication but significant induction of antiviral responses in human monocyte-derived macrophages and dendritic cells.Development of Monoclonal Antibody and Diagnostic Test for Middle East Respiratory Syndrome Coronavirus Using Cell-Free Synthesized Nucleocapsid Antigen.Glycopeptide Antibiotics Potently Inhibit Cathepsin L in the Late Endosome/Lysosome and Block the Entry of Ebola Virus, Middle East Respiratory Syndrome Coronavirus (MERS-CoV), and Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV).Identification of Nafamostat as a Potent Inhibitor of Middle East Respiratory Syndrome Coronavirus S Protein-Mediated Membrane Fusion Using the Split-Protein-Based Cell-Cell Fusion Assay.Proteolytic processing of Middle East respiratory syndrome coronavirus spikes expands virus tropismClinical Isolates of Human Coronavirus 229E Bypass the Endosome for Cell Entry.Cell-based antiviral screening against coronaviruses: developing virus-specific and broad-spectrum inhibitorsReceptor variation and susceptibility to Middle East respiratory syndrome coronavirus infection.An update on Middle East respiratory syndrome: 2 years later.Host Factors in Coronavirus Replication.Respiratory syncytial virus (RSV) entry is inhibited by serine protease inhibitor AEBSF when present during an early stage of infection.A molecular arms race between host innate antiviral response and emerging human coronaviruses.Cell Entry of Porcine Epidemic Diarrhea Coronavirus Is Activated by Lysosomal Proteases.TMPRSS2 Isoform 1 Activates Respiratory Viruses and Is Expressed in Viral Target Cells.Update on therapeutic options for Middle East Respiratory Syndrome Coronavirus (MERS-CoV).High secretion of interferons by human plasmacytoid dendritic cells upon recognition of Middle East respiratory syndrome coronavirus.Type II transmembrane serine proteases as potential target for anti-influenza drug discovery.
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Middle East respiratory syndrome coronavirus infection mediated by the transmembrane serine protease TMPRSS2.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 11 September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Middle East respiratory syndro ...... brane serine protease TMPRSS2.
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Middle East respiratory syndro ...... brane serine protease TMPRSS2.
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type
label
Middle East respiratory syndro ...... brane serine protease TMPRSS2.
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Middle East respiratory syndro ...... brane serine protease TMPRSS2.
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altLabel
Middle East respiratory syndro ...... mbrane serine protease TMPRSS2
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prefLabel
Middle East respiratory syndro ...... brane serine protease TMPRSS2.
@en
Middle East respiratory syndro ...... brane serine protease TMPRSS2.
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P2093
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P921
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Middle East respiratory syndro ...... brane serine protease TMPRSS2.
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P2093
Kazuya Shirato
Miyuki Kawase
Shutoku Matsuyama
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P304
12552-12561
P356
10.1128/JVI.01890-13
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P577
2013-09-11T00:00:00Z