T cell-specific deletion of the inositol phosphatase SHIP reveals its role in regulating Th1/Th2 and cytotoxic responses.
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Inositol phosphatase SHIP1 is a primary target of miR-155microRNAs function in CD8+T cell biologymiR-155 is involved in Alzheimer's disease by regulating T lymphocyte functionDifferential roles for the inositol phosphatase SHIP in the regulation of macrophages and lymphocytes.Role of SHIP-1 in the adaptive immune responses to aeroallergen in the airwayT cell IFN-γ suppression following alcohol and burn injury is independent of miRNA155.Lipid signaling in T-cell development and functionRole of miR-155 in the pathogenesis of herpetic stromal keratitis.PI3Ks in lymphocyte signaling and developmentMouse natural killer cell development and maturation are differentially regulated by SHIP-1.PI3K signalling in B- and T-lymphocytes: new developments and therapeutic advancesPhosphoinositide lipid phosphatases: natural regulators of phosphoinositide 3-kinase signaling in T lymphocytes.Phosphatase regulation of immunoreceptor signaling in T cells, B cells and mast cells.Intracellular protease activation in apoptosis and cell-mediated cytotoxicity characterized by cell-permeable fluorogenic protease substrates.Serine protease inhibitor 6 plays a critical role in protecting murine granzyme B-producing regulatory T cells.SHIP limits immunoregulatory capacity in the T-cell compartment.Pathway-based analysis of primary biliary cirrhosis genome-wide association studiesRegulation of T-cell responses by PTENAnnular PIP3 accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse.Inactivation of SHIP1 in T-cell acute lymphoblastic leukemia due to mutation and extensive alternative splicing.B-Cell-Based and Soluble Biomarkers in Body Liquids for Predicting Acute/Chronic Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation.Therapeutic effects of Euphorbia Pekinensis and Glycyrrhiza glabra on Hepatocellular Carcinoma Ascites Partially Via Regulating the Frk-Arhgdib-Inpp5d-Avpr2-Aqp4 Signal Axis.Inhibitor and activator: dual functions for SHIP in immunity and cancer.The Role of the PI3K Signaling Pathway in CD4(+) T Cell Differentiation and Function.Role of inositol poly-phosphatases and their targets in T cell biology.Signals and pathways controlling regulatory T cells.Mir-155, a central modulator of T-cell responses.Granulocyte colony-stimulating factor impairs CD8(+) T cell functionality by interfering with central activation elements.Regulation of immune cell signaling by SHIP1: A phosphatase, scaffold protein, and potential therapeutic target.Epistasis between microRNAs 155 and 146a during T cell-mediated antitumor immunity.Lineage extrinsic and intrinsic control of immunoregulatory cell numbers by SHIP.The Csk-Associated Adaptor PAG Inhibits Effector T Cell Activation in Cooperation with Phosphatase PTPN22 and Dok Adaptors.Role of SHIP1 in Invariant NKT Cell Development and Functions.Dendritic-cell expression of Ship1 regulates Th2 immunity to helminth infection in mice.SHIP1 intrinsically regulates NK cell signaling and education, resulting in tolerance of an MHC class I-mismatched bone marrow graft in micePharmacological targeting of phosphoinositide lipid kinases and phosphatases in the immune system: success, disappointment, and new opportunities.SHIP-1 inhibits CD95/APO-1/Fas-induced apoptosis in primary T lymphocytes and T leukemic cells by promoting CD95 glycosylation independently of its phosphatase activity.The Transcription Factor T-Bet Is Regulated by MicroRNA-155 in Murine Anti-Viral CD8+ T Cells via SHIP-1.Two SHIPs passing in the middle of the immune system.SHIP-1 deficiency in the myeloid compartment is insufficient to induce myeloid expansion or chronic inflammation.
P2860
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P2860
T cell-specific deletion of the inositol phosphatase SHIP reveals its role in regulating Th1/Th2 and cytotoxic responses.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
T cell-specific deletion of th ...... 1/Th2 and cytotoxic responses.
@ast
T cell-specific deletion of th ...... 1/Th2 and cytotoxic responses.
@en
type
label
T cell-specific deletion of th ...... 1/Th2 and cytotoxic responses.
@ast
T cell-specific deletion of th ...... 1/Th2 and cytotoxic responses.
@en
prefLabel
T cell-specific deletion of th ...... 1/Th2 and cytotoxic responses.
@ast
T cell-specific deletion of th ...... 1/Th2 and cytotoxic responses.
@en
P2093
P2860
P356
P1476
T cell-specific deletion of th ...... 1/Th2 and cytotoxic responses.
@en
P2093
Anthony W Chi
Hemanta K Kole
Margaret M Mentink-Kane
Silvia Bolland
Tatyana Tarasenko
Thomas A Wynn
P2860
P304
11382-11387
P356
10.1073/PNAS.0704853104
P407
P577
2007-06-21T00:00:00Z