A dual role for Src homology 2 domain-containing inositol-5-phosphatase (SHIP) in immunity: aberrant development and enhanced function of b lymphocytes in ship -/- mice
about
TAPP1 and TAPP2 are targets of phosphatidylinositol 3-kinase signaling in B cells: sustained plasma membrane recruitment triggered by the B-cell antigen receptorPTEN function: how normal cells control it and tumour cells lose itMicroRNAs in mouse models of lymphoid malignanciesInhibition of the Jun N-terminal protein kinase pathway by SHIP-1, a lipid phosphatase that interacts with the adaptor molecule Dok-3Inositol phosphatase SHIP1 is a primary target of miR-155Src homology 2 domain-containing inositol-5-phosphatase and CCAAT enhancer-binding protein beta are targeted by miR-155 in B cells of Emicro-MiR-155 transgenic miceThe prognostic and functional role of microRNAs in acute myeloid leukemiaA crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activationCarabin deficiency in B cells increases BCR-TLR9 costimulation-induced autoimmunityCIN85 interacting proteins in B cells-specific role for SHIP-1.SHIP-1 increases early oxidative burst and regulates phagosome maturation in macrophages.Differential roles for the inositol phosphatase SHIP in the regulation of macrophages and lymphocytes.Coordinate suppression of B cell lymphoma by PTEN and SHIP phosphatases.Regulation of hematopoietic cell function by inhibitory immunoglobulin G receptors and their inositol lipid phosphatase effectors.ITAMs versus ITIMs: striking a balance during cell regulation.Pathogenic microRNA's in myeloid malignancies.DAP12 overexpression induces osteopenia and impaired early hematopoiesis.Gab3-deficient mice exhibit normal development and hematopoiesis and are immunocompetent.B cell inhibitory receptors and autoimmunity.Src homology 2-containing 5-inositol phosphatase (SHIP) suppresses an early stage of lymphoid cell development through elevated interleukin-6 production by myeloid cells in bone marrowA sensitized genetic system for the analysis of murine B lymphocyte signal transduction pathways dependent on Bruton's tyrosine kinase.T cell-specific deletion of the inositol phosphatase SHIP reveals its role in regulating Th1/Th2 and cytotoxic responses.The phosphoinositide 3-kinase signaling pathway in normal and malignant B cells: activation mechanisms, regulation and impact on cellular functions.Src homology 2 domain-containing inositol 5-phosphatase 1 deficiency leads to a spontaneous allergic inflammation in the murine lung.Phosphatase regulation of immunoreceptor signaling in T cells, B cells and mast cells.SHIP is required for a functional hematopoietic stem cell niche.A role for SHIP in stem cell biology and transplantation.Regulation of T-cell responses by PTENDeletion of microRNA-155 reduces autoantibody responses and alleviates lupus-like disease in the Fas(lpr) mouseAberrant antibody affinity selection in SHIP-deficient B cells.Inhibitor and activator: dual functions for SHIP in immunity and cancer.Lineage extrinsic and intrinsic control of immunoregulatory cell numbers by SHIP.Role of SHIP1 in Invariant NKT Cell Development and Functions.Pharmacological targeting of phosphoinositide lipid kinases and phosphatases in the immune system: success, disappointment, and new opportunities.SHIP deficiency enhances HSC proliferation and survival but compromises homing and repopulation.IL-6 increases B-cell IgG production in a feed-forward proinflammatory mechanism to skew hematopoiesis and elevate myeloid production.Compound heterozygosity for Pten and SHIP augments T-dependent humoral immune responses and cytokine production by CD(4+) T cells.Antinuclear antibodies in autoimmune and allergic diseases.The Lupus-Associated Fcγ Receptor IIb-I232T Polymorphism Results in Impairment in the Negative Selection of Low-Affinity Germinal Center B Cells Via c-Abl in Mice
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P248
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P2860
A dual role for Src homology 2 domain-containing inositol-5-phosphatase (SHIP) in immunity: aberrant development and enhanced function of b lymphocytes in ship -/- mice
description
2000 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2000
@ast
im März 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/03/06)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/03/06)
@nl
наукова стаття, опублікована в березні 2000
@uk
مقالة علمية (نشرت في 6-3-2000)
@ar
name
A dual role for Src homology 2 ...... b lymphocytes in ship -/- mice
@ast
A dual role for Src homology 2 ...... b lymphocytes in ship -/- mice
@en
A dual role for Src homology 2 ...... b lymphocytes in ship -/- mice
@nl
type
label
A dual role for Src homology 2 ...... b lymphocytes in ship -/- mice
@ast
A dual role for Src homology 2 ...... b lymphocytes in ship -/- mice
@en
A dual role for Src homology 2 ...... b lymphocytes in ship -/- mice
@nl
prefLabel
A dual role for Src homology 2 ...... b lymphocytes in ship -/- mice
@ast
A dual role for Src homology 2 ...... b lymphocytes in ship -/- mice
@en
A dual role for Src homology 2 ...... b lymphocytes in ship -/- mice
@nl
P2093
P2860
P921
P1476
A dual role for Src homology 2 ...... b lymphocytes in ship -/- mice
@en
P2093
C. D. Helgason
C. P. Kalberer
G. Krystal
J. E. Damen
N. Pineault
R. K. Humphries
S. M. Chappel
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P304
P407
P577
2000-03-06T00:00:00Z