Studies with glycolysis-deficient cells suggest that production of lactic acid is not the only cause of tumor acidity.
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Potential clinical applications of bimodal PET-MRI or SPECT-MRI agentsHypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H(+) symportersCarbonic Anhydrase Activity Monitored In Vivo by Hyperpolarized 13C-Magnetic Resonance Spectroscopy Demonstrates Its Importance for pH Regulation in Tumors.Targeting acidic diseased tissue: New technology based on use of the pH (Low) Insertion Peptide (pHLIP).Rapid uptake of glucose and lactate, and not hypoxia, induces apoptosis in three-dimensional tumor tissue cultureTransketolase-like 1 expression is modulated during colorectal cancer progression and metastasis formationMetabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis?Assembled microcapsules by doxorubicin and polysaccharide as high effective anticancer drug carriers.Acid-sensitive ion channels and receptorsDoxorubicin-conjugated β-NaYF4:Gd(3+)/Tb(3+) multifunctional, phosphor nanorods: a multi-modal, luminescent, magnetic probe for simultaneous optical and magnetic resonance imaging and an excellent pH-triggered anti-cancer drug delivery nanovehicle.The relationship between extracellular lactate and tumour pH in a murine tumour model of ischaemia-reperfusion.The chronic administration of drugs that inhibit the regulation of intracellular pH: in vitro and anti-tumour effects.The contribution of lactic acid to acidification of tumours: studies of variant cells lacking lactate dehydrogenasepH-sensitive membrane peptides (pHLIPs) as a novel class of delivery agents.Tumor acidity, chemoresistance and proton pump inhibitors.pHLIP peptide targets nanogold particles to tumorsEffects of tumour acidification with glucose+MIBG on the spontaneous metastatic potential of two murine cell lines.Probe for the measurement of cell surface pH in vivo and ex vivo.Significance of pH regulation and carbonic anhydrases in tumour progression and implications for diagnostic and therapeutic approaches.Novel pH-Sensitive Cyclic PeptidesTumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer.Targeting pancreatic ductal adenocarcinoma acidic microenvironmentImaging pH and metastasis.Protons and Ca2+: ionic allies in tumor progression?Membrane-active host defense peptides--challenges and perspectives for the development of novel anticancer drugs.Carbonic anhydrase IX, a hypoxia-induced catalytic component of the pH regulating machinery in tumors.The chemistry, physiology and pathology of pH in cancer.Metabolic changes associated with tumor metastasis, part 1: tumor pH, glycolysis and the pentose phosphate pathway.Hypoxia and cellular metabolism in tumour pathophysiology.Synthesis of new N,N'-bis[1-aryl-3-(piperidine-1-yl)propylidene]hydrazine dihydrochlorides and evaluation of their cytotoxicity against human hepatoma and breast cancer cells.pH-triggered drug-releasing magnetic nanoparticles for cancer therapy guided by molecular imaging by MRI.Fluorescence ratio imaging of interstitial pH in solid tumours: effect of glucose on spatial and temporal gradients.Role of epidermal growth factor receptor (EGFR)-signaling versus cellular acidosis via Na+/H+ exchanger1(NHE1)-inhibition in troglitazone-induced growth arrest of breast cancer-derived cells MCF-7.Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH.Transformation by different oncogenes relies on specific metabolic adaptations.Disrupting glucose-6-phosphate isomerase fully suppresses the "Warburg effect" and activates OXPHOS with minimal impact on tumor growth except in hypoxia.Pantoprazole Induces Apoptosis of Leukemic Cells by Inhibiting Expression of P-Glycoprotein/Multidrug Resistance-Associated Protein-1 Through PI3K/AKT/mTOR Signaling.Tumour acidosis: from the passenger to the driver's seat.Rethinking the Combination of Proton Exchanger Inhibitors in Cancer Therapy.Temperature-sensitive gels for intratumoral delivery of β-lapachone: effect of cyclodextrins and ethanol
P2860
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P2860
Studies with glycolysis-deficient cells suggest that production of lactic acid is not the only cause of tumor acidity.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Studies with glycolysis-defici ...... e only cause of tumor acidity.
@ast
Studies with glycolysis-defici ...... e only cause of tumor acidity.
@en
type
label
Studies with glycolysis-defici ...... e only cause of tumor acidity.
@ast
Studies with glycolysis-defici ...... e only cause of tumor acidity.
@en
prefLabel
Studies with glycolysis-defici ...... e only cause of tumor acidity.
@ast
Studies with glycolysis-defici ...... e only cause of tumor acidity.
@en
P2093
P2860
P356
P1476
Studies with glycolysis-defici ...... e only cause of tumor acidity.
@en
P2093
P2860
P304
P356
10.1073/PNAS.90.3.1127
P407
P577
1993-02-01T00:00:00Z