Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis.
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Ovarian clear cell carcinoma meets metabolism; HNF-1β confers survival benefits through the Warburg effect and ROS reductionARPKD and early manifestations of ADPKD: the original polycystic kidney disease and phenocopiesSystematic genetic analysis identifies Cis-eQTL target genes associated with glioblastoma patient survivalApproaches to integrating germline and tumor genomic data in cancer research.Identification of candidate genes for prostate cancer-risk SNPs utilizing a normal prostate tissue eQTL data setLaying a solid foundation for Manhattan--'setting the functional basis for the post-GWAS era'.Integrative eQTL-based analyses reveal the biology of breast cancer risk lociEvidence for molecular differences in prostate cancer between African American and Caucasian menExpression QTL-based analyses reveal candidate causal genes and loci across five tumor types.Limited evidence that cancer susceptibility regions are preferential targets for somatic mutationKey regulators in prostate cancer identified by co-expression module analysisAssociation of prostate cancer risk variants with gene expression in normal and tumor tissue.Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk.HNF1B polymorphism influences the prognosis of endometrial cancer patients: a cohort studyThe physiological role of drug transporters.Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancerIntegration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions.Prognostic relevance of molecular subtypes and master regulators in pancreatic ductal adenocarcinomaIntegration of copy number and transcriptomics provides risk stratification in prostate cancer: A discovery and validation cohort studymiR-93/miR-106b/miR-375-CIC-CRABP1: a novel regulatory axis in prostate cancer progressionDeconvoluting complex tissues for expression quantitative trait locus-based analyses.Lessons from postgenome-wide association studies: functional analysis of cancer predisposition lociComprehensive functional annotation of 77 prostate cancer risk loci.Cooperative behavior of the nuclear receptor superfamily and its deregulation in prostate cancer.The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers.Variants at IRX4 as prostate cancer expression quantitative trait loci.HNF1B variants associate with promoter methylation and regulate gene networks activated in prostate and ovarian cancer.A genome-wide association study of prostate cancer in West African men.Single nucleotide polymorphisms in clinics: Fantasy or reality for cancer?Three-dimensional culture system identifies a new mode of cetuximab resistance and disease-relevant genes in colorectal cancer.Gene regulatory mechanisms underpinning prostate cancer susceptibility.A spatiotemporal hypothesis for the regulation, role, and targeting of AMPK in prostate cancer.Translating genetic risk factors for prostate cancer to the clinic: 2013 and beyond.Reasoning over genetic variance information in cause-and-effect models of neurodegenerative diseasesAberrant expression of aldehyde dehydrogenase 1A (ALDH1A) subfamily genes in acute lymphoblastic leukaemia is a common feature of T-lineage tumours.Autoantibody biomarkers for the detection of serous ovarian cancer.RNA editing of SLC22A3 drives early tumor invasion and metastasis in familial esophageal cancer.Comparison of miRNA and gene expression profiles between metastatic and primary prostate cancer.Network-directed cis-mediator analysis of normal prostate tissue expression profiles reveals downstream regulatory associations of prostate cancer susceptibility loci.Oesophageal cancer: RNA editing of SLC22A3 mRNAs: causative relevance to familial ESCC?
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Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Genetic and functional analyse ...... prostate cancer pathogenesis.
@ast
Genetic and functional analyse ...... prostate cancer pathogenesis.
@en
type
label
Genetic and functional analyse ...... prostate cancer pathogenesis.
@ast
Genetic and functional analyse ...... prostate cancer pathogenesis.
@en
prefLabel
Genetic and functional analyse ...... prostate cancer pathogenesis.
@ast
Genetic and functional analyse ...... prostate cancer pathogenesis.
@en
P2093
P2860
P50
P356
P1476
Genetic and functional analyse ...... prostate cancer pathogenesis.
@en
P2093
Anna C Schinzel
Ashutosh K Tewari
Bisola C Awoyemi
Brian D Robinson
Chiara Grisanzio
David Takeda
Edward C Stack
Gillian Petrozziello
Helen Ross-Adams
Hiroki Yamada
P2860
P304
11252-11257
P356
10.1073/PNAS.1200853109
P407
P577
2012-06-22T00:00:00Z