Comprehensive functional annotation of 77 prostate cancer risk loci. - Wikidata - awgldk - TriplyDB

Comprehensive functional annotation of 77 prostate cancer risk loci.

Comprehensive functional annotation of 77 prostate cancer risk loci.

http://www.wikidata.org/entity/Q37533894

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Making sense of GWAS: using epigenomics and genome engineering to understand the functional relevance of SNPs in non-coding regions of the human genome Enhancer scanning to locate regulatory regions in genomic loci Winner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data Leveraging Functional-Annotation Data in Trans-ethnic Fine-Mapping Studies.Comprehensive assembly of novel transcripts from unmapped human RNA-Seq data and their association with cancer Identification of candidate genes for prostate cancer-risk SNPs utilizing a normal prostate tissue eQTL data set Exploring functions of long noncoding RNAs across multiple cancers through co-expression network Functional analysis implicating the SNP rs61552325 in ERBB2 as an effector for androgen-insensitive prostate cancer cell invasion.Functional annotation of colon cancer risk SNPs.Enhancer variants: evaluating functions in common disease.Can genome engineering be used to target cancer-associated enhancers?Prostate cancer risk locus at 8q24 as a regulatory hub by physical interactions with multiple genomic loci across the genome.Association of prostate cancer risk variants with gene expression in normal and tumor tissue.In silico functional pathway annotation of 86 established prostate cancer risk variants.A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer.Identification of a Novel Mucin Gene HCG22 Associated With Steroid-Induced Ocular Hypertension Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans.Comprehensively evaluating cis-regulatory variation in the human prostate transcriptome by using gene-level allele-specific expression Cell-type-specific enrichment of risk-associated regulatory elements at ovarian cancer susceptibility loci.Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer Analysis of Prostate Cancer Susceptibility Variants in South African Men: Replicating Associations on Chromosomes 8q24 and 10q11.Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions.Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus.Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer.motifbreakR: an R/Bioconductor package for predicting variant effects at transcription factor binding sites Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer.Genetics of Common Endocrine Disease: The Present and the Future Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation Common genetic variation associated with increased susceptibility to prostate cancer does not increase risk of radiotherapy toxicity.Prostate Cancer Related JAZF1 Gene is Associated with Schizophrenia.The importance of detailed epigenomic profiling of different cell types within organs.TRIM24 Is an Oncogenic Transcriptional Activator in Prostate Cancer.Germline genetic profiling in prostate cancer: latest developments and potential clinical applications.The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers.Functional annotation of sixty-five type-2 diabetes risk SNPs and its application in risk prediction Molecular markers to guide primary radical treatment selection in localized prostate cancer.Demystifying the secret mission of enhancers: linking distal regulatory elements to target genes.Prospective study of DNA methylation at chromosome 8q24 in peripheral blood and prostate cancer risk.Systematic enrichment analysis of potentially functional regions for 103 prostate cancer risk-associated loci.Identification of novel prostate cancer drivers using RegNetDriver: a framework for integration of genetic and epigenetic alterations with tissue-specific regulatory network.

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Comprehensive functional annotation of 77 prostate cancer risk loci.

http://www.wikidata.org/entity/Q37533894

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 30 January 2014

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Comprehensive functional annotation of 77 prostate cancer risk loci.

@en

Comprehensive functional annotation of 77 prostate cancer risk loci.

@nl

type

label

Comprehensive functional annotation of 77 prostate cancer risk loci.

@en

Comprehensive functional annotation of 77 prostate cancer risk loci.

@nl

prefLabel

Comprehensive functional annotation of 77 prostate cancer risk loci.

@en

Comprehensive functional annotation of 77 prostate cancer risk loci.

@nl

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JOURNAL.PGEN.1004102

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Comprehensive functional annotation of 77 prostate cancer risk loci.

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Chunli Yan

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Daniel L Lakeland

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Ellipse/GAME-ON consortium

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Gerhard A Coetzee

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Malaina Gaddis

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Practical consortium

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Suhn Kyong Rhie

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Wange Lu

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Wendy Cozen

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An integrated map of genetic variation from 1,092 human genomes

Prostate cancer susceptibility Loci identified on chromosome 12 in African Americans

Essential role for TAX1BP1 in the termination of TNF-alpha-, IL-1- and LPS-mediated NF-kappaB and JNK signaling

Exploiting transcription factor binding site clustering to identify cis-regulatory modules involved in pattern formation in the Drosophila genome

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

Frequent fusion of the JAZF1 and JJAZ1 genes in endometrial stromal tumors

Determination of tag density required for digital transcriptome analysis: application to an androgen-sensitive prostate cancer model

A genomic code for nucleosome positioning

Most mammalian mRNAs are conserved targets of microRNAs

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e1004102

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scholarly article

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10.1371/JOURNAL.PGEN.1004102

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1

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10

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Houtan Noushmehr

Zsofia Kote-Jarai

Dennis Hazelett

Douglas F. Easton

Christopher A. Haiman

Brian E. Henderson

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2014-01-30T00:00:00Z

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