The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation.
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Neuronal stimulation with 5-hydroxytryptamine 4 receptor induces anti-inflammatory actions via α7nACh receptors on muscularis macrophages associated with postoperative ileusParasympathetic stimulation via the vagus nerve prevents systemic organ dysfunction by abrogating gut injury and lymph toxicity in trauma and hemorrhagic shockModulatory effects of α7 nAChRs on the immune system and its relevance for CNS disordersRole of α7 nicotinic receptor in the immune system and intracellular signaling pathwaysThe human CHRNA7 and CHRFAM7A genes: A review of the genetics, regulation, and functionCHRFAM7A, a human-specific and partially duplicated α7-nicotinic acetylcholine receptor gene with the potential to specify a human-specific inflammatory response to injuryDimeric -Cobratoxin X-ray Structure: LOCALIZATION OF INTERMOLECULAR DISULFIDES AND POSSIBLE MODE OF BINDING TO NICOTINIC ACETYLCHOLINE RECEPTORSAnti-allergic role of cholinergic neuronal pathway via α7 nicotinic ACh receptors on mucosal mast cells in a murine food allergy modelNicotinic receptor subunit alpha5 modifies assembly, up-regulation, and response to pro-inflammatory cytokinesUltrasound Modulates the Splenic Neuroimmune Axis in Attenuating AKI.Looking below the surface of nicotinic acetylcholine receptorsIntrinsically low open probability of α7 nicotinic acetylcholine receptors can be overcome by positive allosteric modulation and serum factors leading to the generation of excitotoxic currents at physiological temperaturesTemporal-logic analysis of microglial phenotypic conversion with exposure to amyloid-β.ELIC-α7 Nicotinic acetylcholine receptor (α7nAChR) chimeras reveal a prominent role of the extracellular-transmembrane domain interface in allosteric modulation.Anti-inflammatory effects of the nicotinergic peptides SLURP-1 and SLURP-2 on human intestinal epithelial cells and immunocytesTargeting Abeta and tau in Alzheimer's disease, an early interim reportGTS-21, an α7-nicotinic acetylcholine receptor agonist, modulates Th1 differentiation in CD4(+) T cells from patients with rheumatoid arthritisFuture therapeutic targets in rheumatoid arthritis?Activation and inhibition of mouse muscle and neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes.Selective alpha7 nicotinic acetylcholine receptor agonists worsen disease in experimental colitis.Intrathecal injection of an alpha seven nicotinic acetylcholine receptor agonist attenuates gp120-induced mechanical allodynia and spinal pro-inflammatory cytokine profiles in rats.Nicotinic receptor Alpha7 expression during mouse adrenal gland developmentAlpha 7 subunit of nAChR regulates migration of human mesenchymal stem cells.The minimal pharmacophore for silent agonism of the α7 nicotinic acetylcholine receptor.{alpha}7-nAChR-mediated suppression of hyperexcitability of colonic dorsal root ganglia neurons in experimental colitisA nicotinic receptor-mediated anti-inflammatory effect of the flavonoid rhamnetin in BV2 microglia.α7 nicotinic acetylcholine receptor-mediated neuroprotection against dopaminergic neuron loss in an MPTP mouse model via inhibition of astrocyte activation.Tethered agonist analogs as site-specific probes for domains of the human α7 nicotinic acetylcholine receptor that differentially regulate activation and desensitization.Merging old and new perspectives on nicotinic acetylcholine receptorsIdentification of novel α7 nicotinic receptor ligands by in silico screening against the crystal structure of a chimeric α7 receptor ligand binding domainNicotine exerts an anti-inflammatory effect in a murine model of acute lung injury.Alpha7 cholinergic-agonist prevents systemic inflammation and improves survival during resuscitationCytokine-induced alterations of α7 nicotinic receptor in colonic CD4 T cells mediate dichotomous response to nicotine in murine models of Th1/Th17- versus Th2-mediated colitis.The effective opening of nicotinic acetylcholine receptors with single agonist binding sitesElectrophysiological perspectives on the therapeutic use of nicotinic acetylcholine receptor partial agonistsα7-cholinergic receptor mediates vagal induction of splenic norepinephrine.JAK2 inhibition prevents innate immune responses and rescues animals from sepsis.Neuregulin upregulates microglial α7 nicotinic acetylcholine receptor expression in immortalized cell lines: implications for regulating neuroinflammationInvolvement of MAPK/NF-κB signaling in the activation of the cholinergic anti-inflammatory pathway in experimental colitis by chronic vagus nerve stimulationThe analgesic-like properties of the alpha7 nAChR silent agonist NS6740 is associated with non-conducting conformations of the receptor.
P2860
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P2860
The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation.
@ast
The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation.
@en
type
label
The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation.
@ast
The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation.
@en
prefLabel
The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation.
@ast
The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation.
@en
P2860
P356
P1476
The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation
@en
P2093
W J de Jonge
P2860
P304
P356
10.1038/SJ.BJP.0707264
P407
P50
P577
2007-05-14T00:00:00Z