Breast cancer cell uptake of the inflammatory mediator neutrophil elastase triggers an anticancer adaptive immune response
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Tumor-Induced Local and Systemic Impact on Blood Vessel FunctionThe new deal: a potential role for secreted vesicles in innate immunity and tumor progressionNeutrophils in the tumor microenvironment: trying to heal the wound that cannot heal.Essential role of the cancer stem/progenitor cell marker nucleostemin for indole-3-carbinol anti-proliferative responsiveness in human breast cancer cells.Tumor associated macrophages and neutrophils in tumor progression.Elafin is downregulated during breast and ovarian tumorigenesis but its residual expression predicts recurrence.The serine protease inhibitor elafin maintains normal growth control by opposing the mitogenic effects of neutrophil elastase.Clathrin pit-mediated endocytosis of neutrophil elastase and cathepsin G by cancer cells.Broad cross-presentation of the hematopoietically derived PR1 antigen on solid tumors leads to susceptibility to PR1-targeted immunotherapy.Neutrophil elastase promotes myofibroblast differentiation in lung fibrosis.A proposed role for neutrophil extracellular traps in cancer immunoediting.Neutrophil elastase enhances the proliferation and decreases apoptosis of leukemia cells via activation of PI3K/Akt signaling.Elafin, an inhibitor of elastase, is a prognostic indicator in breast cancerThe immune system and inflammation in breast cancer.Enzyme-activatable imaging probe reveals enhanced neutrophil elastase activity in tumors following photodynamic therapy.Insulin receptor substrate-1 deficiency drives a proinflammatory phenotype in KRAS mutant lung adenocarcinoma.Neutrophil elastase cleavage of the gC1q domain impairs the EMILIN1-α4β1 integrin interaction, cell adhesion and anti-proliferative activityPromoting effect of neutrophils on lung tumorigenesis is mediated by CXCR2 and neutrophil elastase.Neutrophil elastase as a diagnostic marker and therapeutic target in colorectal cancers.PD-L1 expression in triple-negative breast cancer.Protumor and antitumor functions of neutrophil granulocytes.Neutrophils in innate and adaptive immunity.A Strong Neutrophil Elastase Proteolytic Fingerprint Marks the Carcinoma Tumor Proteome.Impact of the immune system and immunotherapy in colorectal cancer.Neuropilin-1 mediates neutrophil elastase uptake and cross-presentation in breast cancer cells.Neutrophil elastase enhances antigen presentation by upregulating human leukocyte antigen class I expression on tumor cells.Type I IFNs induce anti-tumor polarization of tumor associated neutrophils in mice and human.Modulating the innate immune activity in murine tumor microenvironment by a combination of inducer molecules attached to microparticles.Neutral serine proteases of neutrophils.NETs in cancer.One microenvironment does not fit all: heterogeneity beyond cancer cells.Mouse versus Human Neutrophils in Cancer: A Major Knowledge Gap.Cathepsin G Is Expressed by Acute Lymphoblastic Leukemia and Is a Potential Immunotherapeutic Target.Roles of neutrophils in cancer growth and progression.Phase Ib trial of folate binding protein (FBP)-derived peptide vaccines, E39 and an attenuated version, E39': An analysis of safety and immune response.Neutrophil infiltration favors colitis-associated tumorigenesis by activating the interleukin-1 (IL-1)/IL-6 axis.Serine Proteases Enhance Immunogenic Antigen Presentation on Lung Cancer Cells.
P2860
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P2860
Breast cancer cell uptake of the inflammatory mediator neutrophil elastase triggers an anticancer adaptive immune response
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Breast cancer cell uptake of t ...... ancer adaptive immune response
@ast
Breast cancer cell uptake of t ...... ancer adaptive immune response
@en
type
label
Breast cancer cell uptake of t ...... ancer adaptive immune response
@ast
Breast cancer cell uptake of t ...... ancer adaptive immune response
@en
prefLabel
Breast cancer cell uptake of t ...... ancer adaptive immune response
@ast
Breast cancer cell uptake of t ...... ancer adaptive immune response
@en
P2093
P2860
P1433
P1476
Breast cancer cell uptake of t ...... ancer adaptive immune response
@en
P2093
Anne V Philips
Elizabeth A Mittendorf
Gheath Alatrash
Haile Xiao
Jeffrey J Molldrem
Karen Clise-Dwyer
Kathryn Ruisaard
Lisa S St John
P2860
P304
P356
10.1158/0008-5472.CAN-11-4135
P407
P577
2012-05-07T00:00:00Z