Animal cell cultures: recent achievements and perspectives in the production of biopharmaceuticals.
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Recent advances in sialic acid-focused glycomicsIncreasing batch-to-batch reproducibility of CHO cultures by robust open-loop control.Online- and offline- monitoring of stem cell expansion on microcarrier.Fermentanomics: Relating quality attributes of a monoclonal antibody to cell culture process variables and raw materials using multivariate data analysis.Characterization of chromatographic yeast extract fractions promoting CHO cell growth.Differential protein expression following low temperature culture of suspension CHO-K1 cellsThe chimeric monoclonal antibody MHCSZ-123 against human von Willebrand factor A3 domain inhibits high-shear arterial thrombosis in a Rhesus monkey modelFluorescent labeling in semi-solid medium for selection of mammalian cells secreting high-levels of recombinant proteinsCentralized modularity of N-linked glycosylation pathways in mammalian cells.High throughput quantification of N-glycans using one-pot sialic acid modification and matrix assisted laser desorption ionization time-of-flight mass spectrometryEngineering host cell lines to reduce terminal sialylation of secreted antibodies.Influence of aeration-homogenization system in stirred tank bioreactors, dissolved oxygen concentration and pH control mode on BHK-21 cell growth and metabolism.High-throughput sorting of the highest producing cell via a transiently protein-anchored systemHost cell protein dynamics in the supernatant of a mAb producing CHO cell line.Cell culture processes for monoclonal antibody production.Anti-TNFα domain antibody construct CEP-37247: Full antibody functionality at half the size.Production of functional soluble Dectin-1 glycoprotein using an IRES-linked destabilized-dihydrofolate reductase expression vectorAccomplishments in genome-scale in silico modeling for industrial and medical biotechnologyReduction in C-terminal amidated species of recombinant monoclonal antibodies by genetic modification of CHO cells.EB66 cell line, a duck embryonic stem cell-derived substrate for the industrial production of therapeutic monoclonal antibodies with enhanced ADCC activity.A Single Dynamic Metabolic Model Can Describe mAb Producing CHO Cell Batch and Fed-Batch Cultures on Different Culture Media.Analytical detection and characterization of biopharmaceutical glycosylation by MS.5-thiomannosides block the biosynthesis of dolichol-linked oligosaccharides and mimic class I congenital disorders of glycosylationMicroRNAs: recently discovered key regulators of proliferation and apoptosis in animal cells : Identification of miRNAs regulating growth and survival.Communication networks beyond the capacity crunch.Post-translational modifications in the context of therapeutic proteins.The effects of culture conditions on the glycosylation of secreted human placental alkaline phosphatase produced in Chinese hamster ovary cells.Emerging trends in plasma-free manufacturing of recombinant protein therapeutics expressed in mammalian cells.Using cell engineering and omic tools for the improvement of cell culture processes.Engineering mammalian cells in bioprocessing - current achievements and future perspectives.Over-expression of secreted proteins from mammalian cell lines.GlycoFi's technology to control the glycosylation of recombinant therapeutic proteins.Recent advances in technology supporting biopharmaceutical production from mammalian cells.An 'omics approach towards CHO cell engineering.Current state and recent advances in biopharmaceutical production in Escherichia coli, yeasts and mammalian cells.High-throughput transfection and engineering of primary cells and cultured cell lines - an invaluable tool for research as well as drug development.Autophagy and its implication in Chinese hamster ovary cell culture.Expression of recombinant antibodies.Glycosylation: impact, control and improvement during therapeutic protein production.New technologies for measuring single cell mass.
P2860
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P2860
Animal cell cultures: recent achievements and perspectives in the production of biopharmaceuticals.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Animal cell cultures: recent a ...... duction of biopharmaceuticals.
@ast
Animal cell cultures: recent a ...... duction of biopharmaceuticals.
@en
type
label
Animal cell cultures: recent a ...... duction of biopharmaceuticals.
@ast
Animal cell cultures: recent a ...... duction of biopharmaceuticals.
@en
prefLabel
Animal cell cultures: recent a ...... duction of biopharmaceuticals.
@ast
Animal cell cultures: recent a ...... duction of biopharmaceuticals.
@en
P1476
Animal cell cultures: recent a ...... duction of biopharmaceuticals.
@en
P2093
Michael Butler
P2888
P304
P356
10.1007/S00253-005-1980-8
P407
P577
2005-04-16T00:00:00Z