Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage.
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The effect of OPA1 on mitochondrial Ca²⁺ signalingPINK1 is selectively stabilized on impaired mitochondria to activate ParkinInducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cellsYME1L controls the accumulation of respiratory chain subunits and is required for apoptotic resistance, cristae morphogenesis, and cell proliferationLoss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in miceThe novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cellsC11orf83, a mitochondrial cardiolipin-binding protein involved in bc1 complex assembly and supercomplex stabilizationBroad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagyMitochondrial morphology-emerging role in bioenergeticsCell signaling and mitochondrial dynamics: Implications for neuronal function and neurodegenerative diseaseMitophagy: mechanisms, pathophysiological roles, and analysisMitochondrial form and functionMorphological control of mitochondrial bioenergeticsMechanisms of mitochondria and autophagy crosstalkWhy mitochondria must fuse to maintain their genome integrityThe C. elegans Opa1 homologue EAT-3 is essential for resistance to free radicalsA mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondriaMitochondrial Quality Control in Cardiac DiseasesKey Targets for Multi-Target Ligands Designed to Combat NeurodegenerationMitochondrial protein quality control: the mechanisms guarding mitochondrial healthMultifaceted role of prohibitin in cell survival and apoptosisHomozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentationThe i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fissionYME1L degradation reduces mitochondrial proteolytic capacity during oxidative stressImbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in miceMitochondrial fragmentation in neurodegenerationA novel deletion in the GTPase domain of OPA1 causes defects in mitochondrial morphology and distribution, but not in functionThe AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnoverMitochondrial function in vascular endothelial cell in diabetesMitochondrial morphology in metabolic diseasesDisruption of cytochrome c heme coordination is responsible for mitochondrial injury during ischemiaMitochondrial dynamics and mitochondrial quality controlMembrane trafficking. Nucleoside diphosphate kinases fuel dynamin superfamily proteins with GTP for membrane remodelingAutocatalytic processing of m-AAA protease subunits in mitochondriaRegulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1SLP-2 is required for stress-induced mitochondrial hyperfusionProteasome and p97 mediate mitophagy and degradation of mitofusins induced by ParkinMitochondrial dynamics and apoptosisThe Interplay between Oncogenic Signaling Networks and Mitochondrial Dynamics.New insights into mitochondrial structure during cell death.
P2860
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P2860
Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage.
@ast
Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage.
@en
type
label
Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage.
@ast
Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage.
@en
prefLabel
Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage.
@ast
Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage.
@en
P2093
P2860
P356
P1476
Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage.
@en
P2093
Alexander M van der Bliek
Lorena Griparic
Takayuki Kanazawa
P2860
P304
P356
10.1083/JCB.200704112
P407
P577
2007-08-20T00:00:00Z