14-3-3 inhibition promotes dopaminergic neuron loss and 14-3-3θ overexpression promotes recovery in the MPTP mouse model of Parkinson's disease.

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14-3-3 Proteins regulate mutant LRRK2 kinase activity and neurite shortening.Dysregulation of 14-3-3 proteins in neurodegenerative diseases with Lewy body or Alzheimer pathology.

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14-3-3 inhibition promotes dopaminergic neuron loss and 14-3-3θ overexpression promotes recovery in the MPTP mouse model of Parkinson's disease.

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http://www.wikidata.org/entity/Q36126310

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2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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name

14-3-3 inhibition promotes dop ...... model of Parkinson's disease.

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14-3-3 inhibition promotes dop ...... model of Parkinson's disease.

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14-3-3 inhibition promotes dop ...... model of Parkinson's disease.

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14-3-3 inhibition promotes dop ...... model of Parkinson's disease.

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14-3-3 inhibition promotes dop ...... model of Parkinson's disease.

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14-3-3 inhibition promotes dop ...... model of Parkinson's disease.

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P1476

14-3-3 inhibition promotes dop ...... model of Parkinson's disease.

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H Ding

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N Lavalley

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R Underwood

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T A Yacoubian

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P2860

NIH Image to ImageJ: 25 years of image analysis

The chaperone-like protein 14-3-3η interacts with human α-synuclein aggregation intermediates rerouting the amyloidogenic pathway and reducing α-synuclein cellular toxicity

14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization

14-3-3eta is a novel regulator of parkin ubiquitin ligase.

SLITRK1 binds 14-3-3 and regulates neurite outgrowth in a phosphorylation-dependent manner

alpha-Synuclein shares physical and functional homology with 14-3-3 proteins

14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome

DEGAS: de novo discovery of dysregulated pathways in human diseases

Phosphorylation-dependent 14-3-3 binding to LRRK2 is impaired by common mutations of familial Parkinson's disease

Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

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scholarly article

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10.1016/J.NEUROSCIENCE.2015.08.042

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English

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2015-08-24T00:00:00Z

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26314634

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overexpression

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14-3-3 inhibition promotes dopaminergic neuron loss and 14-3-3θ overexpression promotes recovery in the MPTP mouse model of Parkinson's disease.

about

P2860

P2860

14-3-3 inhibition promotes dopaminergic neuron loss and 14-3-3θ overexpression promotes recovery in the MPTP mouse model of Parkinson's disease.

description

name

type

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P1433

P1476

P2093

P2860

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P356

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P478

P577

P5875

P698

P921

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P1433

P1476

P2093

P2860

P304

P31

P356

P407

P478

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P5875

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P932