Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice. - Wikidata - awgldk - TriplyDB

Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice.

Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice.

http://www.wikidata.org/entity/Q36132667

about

Immune Regulation and Antitumor Effect of TIM-1 The clearance of dying cells: table for two Role of B cells in tolerance induction Phosphatidylserine receptors: enhancers of enveloped virus entry and infection TIM-1 signaling is required for maintenance and induction of regulatory B cells.Contribution of Defective PS Recognition and Efferocytosis to Chronic Inflammation and Autoimmunity Characterizing functional domains for TIM-mediated enveloped virus entry TIM-1 glycoprotein binds the adhesion receptor P-selectin and mediates T cell trafficking during inflammation and autoimmunity Insulin-like growth factor-2 enhances functions of antigen (Ag)-specific regulatory B cells.Dysregulated cytokine production by dendritic cells modulates B cell responses in the NZM2410 mouse model of lupus Generation and identification of tumor-evoked regulatory B cells IL-10-producing B cells are induced early in HIV-1 infection and suppress HIV-1-specific T cell responses.Tim-1 is essential for induction and maintenance of IL-10 in regulatory B cells and their regulation of tissue inflammation.Accelerated receptor shedding inhibits kidney injury molecule-1 (KIM-1)-mediated efferocytosis.KIM-1-mediated phagocytosis reduces acute injury to the kidney.Regulatory B Cell Function Is Suppressed by Smoking and Obesity in H. pylori-Infected Subjects and Is Correlated with Elevated Risk of Gastric Cancer.Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy.Renal Transplant Recipients Treated with Calcineurin-Inhibitors Lack Circulating Immature Transitional CD19+CD24hiCD38hi Regulatory B-Lymphocytes New insights into B cell biology in systemic lupus erythematosus and Sjögren's syndrome KIM-1-/TIM-1-mediated phagocytosis links ATG5-/ULK1-dependent clearance of apoptotic cells to antigen presentation.T-cell immunoglobulin and mucin domain 1 deficiency eliminates airway hyperreactivity triggered by the recognition of airway cell death.Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis.TIM-1 defines a human regulatory B cell population that is altered in frequency and function in systemic sclerosis patients.Contributions of B cells to lupus pathogenesis Regulatory functions of B cells in allergic diseases.Signals controlling the development and activity of regulatory B-lineage cells.The expanding family of regulatory B cells.Negative immune checkpoints on T lymphocytes and their relevance to cancer immunotherapy.Expression of Tim-1 in primary CNS lymphoma.Potential importance of B cells in aging and aging-associated neurodegenerative diseases.Immune checkpoint proteins: exploring their therapeutic potential to regulate atherosclerosis.CD19+ Tim-1+ B cells are decreased and negatively correlated with disease severity in Myasthenia Gravis patients.IL-21/anti-Tim1/CD40 ligand promotes B10 activity in vitro and alleviates bone loss in experimental periodontitis in vivo.What do we know about the role of regulatory B cells (Breg) during the course of infection of two major parasitic diseases, malaria and leishmaniasis?TGF-β-producing regulatory B cells induce regulatory T cells and promote transplantation tolerance.Apoptosis inhibitor of macrophage protein enhances intraluminal debris clearance and ameliorates acute kidney injury in mice.Endogenous Tim-1 promotes severe systemic autoimmunity and renal disease MRL-Fas(lpr) mice.Reduced numbers of regulatory B cells are negatively correlated with disease activity in patients with new-onset rheumatoid arthritis.KIM-1/TIM-1 in proximal tubular cell immune response.miR-21 silencing ameliorates experimental autoimmune encephalomyelitis by promoting the differentiation of IL-10-producing B cells.

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Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice.

http://www.wikidata.org/entity/Q36132667

description

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2012年论文

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name

Defect in regulatory B-cell fu ...... m-1) mucin domain-mutant mice.

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Defect in regulatory B-cell fu ...... m-1) mucin domain-mutant mice.

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Defect in regulatory B-cell fu ...... m-1) mucin domain-mutant mice.

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PNAS.1120914109

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Proceedings of the National Academy of Sciences of the United States of America

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Defect in regulatory B-cell fu ...... im-1) mucin domain-mutant mice

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Ada Yeste

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Chen Zhu

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Craig R Brooks

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Francisco J Quintana

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Joseph V Bonventre

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Raymond A Sobel

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Sheng Xiao

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Sonia Petecka

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Takaharu Ichimura

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Vijay K Kuchroo

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P2860

The Cys-rich region of hepatitis A virus cellular receptor 1 is required for binding of hepatitis A virus and protective monoclonal antibody 190/4

The human homolog of HAVcr-1 codes for a hepatitis A virus cellular receptor

TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells.

Structures of T Cell Immunoglobulin Mucin Protein 4 Show a Metal-Ion-Dependent Ligand Binding Site where Phosphatidylserine Binds

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family

Immunology: hepatitis A virus link to atopic disease

TIM-1 induces T cell activation and inhibits the development of peripheral tolerance

TIM-1, a novel allergy and asthma susceptibility gene

Regulation of tolerance in the respiratory tract: TIM-1, hygiene, and the environment

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12105-12110

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228447290

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22773818

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3409739

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