Cisplatin and taxol activate different signal pathways regulating cellular injury-induced expression of GADD153 - Wikidata - awgldk - TriplyDB

Cisplatin and taxol activate different signal pathways regulating cellular injury-induced expression of GADD153

Cisplatin and taxol activate different signal pathways regulating cellular injury-induced expression of GADD153

http://www.wikidata.org/entity/Q36134430

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CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum Expression of the pro-apoptotic gene gadd153/chop is elevated in liver with aging and sensitizes cells to oxidant injury Mifepristone prevents repopulation of ovarian cancer cells escaping cisplatin-paclitaxel therapy.Aberrant Schwann cell lipid metabolism linked to mitochondrial deficits leads to axon degeneration and neuropathy.Parathyroid hormone suppresses osteoblast apoptosis by augmenting DNA repair Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response.p12(CDK2-AP1) mediates DNA damage responses induced by cisplatin.Induction of gadd153 mRNA by nutrient deprivation is overcome by glutamine.Quantification of tumor cell injury in vitro and in vivo using expression of green fluorescent protein under the control of the GADD153 promoter.Paclitaxel activation of the GADD153 promoter through a cellular injury response element containing an essential Sp1 binding site.

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Cisplatin and taxol activate different signal pathways regulating cellular injury-induced expression of GADD153

http://www.wikidata.org/entity/Q36134430

description

1996 nî lūn-bûn

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Cisplatin and taxol activate d ...... -induced expression of GADD153

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Cisplatin and taxol activate d ...... -induced expression of GADD153

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Cisplatin and taxol activate d ...... -induced expression of GADD153

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Cisplatin and taxol activate d ...... -induced expression of GADD153

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Cisplatin and taxol activate d ...... -induced expression of GADD153

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Cisplatin and taxol activate d ...... -induced expression of GADD153

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British Journal of Cancer

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Cisplatin and taxol activate d ...... -induced expression of GADD153

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A Sharma

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D P Gately

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R D Christen

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S B Howell

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P2860

Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma

Isolation, characterization and chromosomal localization of the human GADD153 gene

DNA damage-inducible transcripts in mammalian cells

Rearrangement of the transcription factor gene CHOP in myxoid liposarcomas with t(12;16)(q13;p11)

Genotoxic-stress-response genes and growth-arrest genes. gadd, MyD, and other genes induced by treatments eliciting growth arrest

Analysis of the mammalian gadd45 gene and its response to DNA damage

CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription

Tyrphostins. 2. Heterocyclic and alpha-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases

Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

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