p12(CDK2-AP1) mediates DNA damage responses induced by cisplatin.
about
Targeted inactivation of p12, CDK2 associating protein 1, leads to early embryonic lethalityMutation of Cys105 inhibits dimerization of p12CDK2-AP1 and its growth suppressor effect.CDK2-AP1 inhibits growth of breast cancer cells by regulating cell cycle and increasing docetaxel sensitivity in vivo and in vitroEfavirenz induces autophagy and aberrant differentiation in normal human keratinocytes.Cyclin-dependent kinase 2-associating protein 1 commits murine embryonic stem cell differentiation through retinoblastoma protein regulation.Clinical aggressiveness of myxofibrosarcomas associates with down-regulation of p12CDK2AP1: prognostic implication of a putative tumor suppressor that induces cell cycle arrest and apoptosis via mitochondrial pathway.Cdk2ap1 is required for epigenetic silencing of Oct4 during murine embryonic stem cell differentiation.
P2860
Q28512766-04D026BA-86C8-4438-97D8-87AA2D102ED6Q34412512-6D70EF18-2557-4377-ACDB-08E6B806B47DQ34787090-22D8AF49-D529-4C40-8E83-7122101040C9Q36954593-7E0B020F-8B69-4A22-A147-9D16FB7A1DC0Q37358116-C4405518-DDA5-4E04-8F92-56399FD110ABQ38989078-C38BDA21-6CB9-4055-BB50-A87BEE88E7F2Q39899717-1BCE5A11-6650-42B2-B23E-59EA2C45AFA0
P2860
p12(CDK2-AP1) mediates DNA damage responses induced by cisplatin.
description
2005 nî lūn-bûn
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name
p12(CDK2-AP1) mediates DNA damage responses induced by cisplatin.
@en
type
label
p12(CDK2-AP1) mediates DNA damage responses induced by cisplatin.
@en
prefLabel
p12(CDK2-AP1) mediates DNA damage responses induced by cisplatin.
@en
P2093
P2860
P356
P1433
P1476
p12(CDK2-AP1) mediates DNA damage responses induced by cisplatin.
@en
P2093
David T Wong
Jim McBride
Rong Zhang
Xiaofeng Zhou
P2860
P2888
P304
P356
10.1038/SJ.ONC.1208222
P407
P577
2005-01-01T00:00:00Z
P5875
P6179
1004006216