β-Arrestin2 mediates the initiation and progression of myeloid leukemia.
about
β-arrestin1 at the cross-road of endothelin-1 signaling in cancerThe emerging roles of β-arrestins in fibrotic diseasesβArrestin1 regulates the guanine nucleotide exchange factor RasGRF2 expression and the small GTPase Rac-mediated formation of membrane protrusion and cell motility.β-Arrestin1 promotes the progression of chronic myeloid leukaemia by regulating BCR/ABL H4 acetylation.Targeted disruption of β-arrestin 2-mediated signaling pathways by aptamer chimeras leads to inhibition of leukemic cell growth.Delineation of a conserved arrestin-biased signaling repertoire in vivo.Fulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism.Informatic deconvolution of biased GPCR signaling mechanisms from in vivo pharmacological experimentation.Gene dosage-dependent negative regulatory role of β-arrestin-2 in polymicrobial infection-induced inflammation.Emerging therapeutic strategies for targeting chronic myeloid leukemia stem cellsKisspeptin/KISS1R System in Breast CancerMultifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention.Stem cell maintenance and disease progression in chronic myeloid leukemia.New prospects for drug development: the hedgehog pathway revealed. Focus on hematologic malignancies.The cellular senescence of leukemia-initiating cells from acute lymphoblastic leukemia is postponed by β-Arrestin1 binding with P300-Sp1 to regulate hTERT transcription.Cross talk between Wnt/β-catenin and Irf8 in leukemia progression and drug resistance.β-Arrestin2 mediates progression of murine primary myelofibrosis.Molecular evidence and clinical importance of β-arrestins expression in patients with acromegaly.βArrestin2 Mediates Renal Cell Carcinoma Tumor Growth.
P2860
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P2860
β-Arrestin2 mediates the initiation and progression of myeloid leukemia.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
β-Arrestin2 mediates the initiation and progression of myeloid leukemia.
@ast
β-Arrestin2 mediates the initiation and progression of myeloid leukemia.
@en
type
label
β-Arrestin2 mediates the initiation and progression of myeloid leukemia.
@ast
β-Arrestin2 mediates the initiation and progression of myeloid leukemia.
@en
prefLabel
β-Arrestin2 mediates the initiation and progression of myeloid leukemia.
@ast
β-Arrestin2 mediates the initiation and progression of myeloid leukemia.
@en
P2093
P2860
P356
P1476
β-Arrestin2 mediates the initiation and progression of myeloid leukemia
@en
P2093
Hyog Young Kwon
Jeffrey J Kovacs
Mark Fereshteh
Minyong Chen
Robert J Lefkowitz
Tannishtha Reya
Valerie Tornini
P2860
P304
12532-12537
P356
10.1073/PNAS.1209815109
P407
P577
2012-07-05T00:00:00Z