Sodium channels as macromolecular complexes: implications for inherited arrhythmia syndromes.
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Sodium channel Scn1b null mice exhibit prolonged QT and RR intervalsSudden infant death syndrome-associated mutations in the sodium channel beta subunitsMutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillationIdentification of a new co-factor, MOG1, required for the full function of cardiac sodium channel Nav 1.5Voltage-gated ion channel dysfunction precedes cardiomyopathy development in the dystrophic heartSodium channel β1 subunit mutations associated with Brugada syndrome and cardiac conduction disease in humansSCN4B-encoded sodium channel beta4 subunit in congenital long-QT syndromeMutations in sodium channel β1- and β2-subunits associated with atrial fibrillationMultiple arrhythmic syndromes in a newborn, owing to a novel mutation in SCN5AThe role of late I Na in development of cardiac arrhythmiasChannelopathies from mutations in the cardiac sodium channel protein complexThe late Na+ current--origin and pathophysiological relevanceXin proteins and intercalated disc maturation, signaling and diseasesSmall-conductance Ca2+ -activated K+ channels and cardiac arrhythmiasLate Na(+) current and protracted electrical recovery are critical determinants of the aging myopathyNanoscale visualization of functional adhesion/excitability nodes at the intercalated disc.Intercalated disc abnormalities, reduced Na(+) current density, and conduction slowing in desmoglein-2 mutant mice prior to cardiomyopathic changesPost-translational modifications of the cardiac Na channel: contribution of CaMKII-dependent phosphorylation to acquired arrhythmiasHuman and rat Nav1.3 voltage-gated sodium channels differ in inactivation properties and sensitivity to the pyrethroid insecticide tefluthrinRecent developments in the management of patients at risk for sudden cardiac death.The role of ion channelopathies in sudden cardiac death: implications for clinical practice.Cloning and expression of a zebrafish SCN1B ortholog and identification of a species-specific splice variant.Molecular cloning and analysis of zebrafish voltage-gated sodium channel beta subunit genes: implications for the evolution of electrical signaling in vertebrates.A mutation in the beta 3 subunit of the cardiac sodium channel associated with Brugada ECG phenotypeDystrophic Cardiomyopathy-Potential Role of Calcium in Pathogenesis, Treatment and Novel TherapiesCardiac ablation of Rheb1 reduces sodium currents in infant miceVoltage-gated sodium channels are required for heart development in zebrafish.State-Dependent Modification of Voltage-Gated Sodium Channels by Pyrethroids.Tubulin polymerization disrupts cardiac β-adrenergic regulation of late INa.Na Channel β Subunits: Overachievers of the Ion Channel Family.Extracellular proton depression of peak and late Na⁺ current in the canine left ventricle.Post-transcriptional silencing of SCN1B and SCN2B genes modulates late sodium current in cardiac myocytes from normal dogs and dogs with chronic heart failure.Molecular mechanisms of pyrethroid insecticide neurotoxicity: recent advances.Differential state-dependent modification of rat Na(v)1.6 sodium channels expressed in human embryonic kidney (HEK293) cells by the pyrethroid insecticides tefluthrin and deltamethrin.Pharmacogenomics of cardiovascular complications in diabetes and obesity.Striking In vivo phenotype of a disease-associated human SCN5A mutation producing minimal changes in vitroCoexpression with Auxiliary β Subunits Modulates the Action of Tefluthrin on Rat Na(v)1.6 and Na(v)1.3 Sodium ChannelsCompound heterozygous mutations P336L and I1660V in the human cardiac sodium channel associated with the Brugada syndrome.An emerging role for voltage-gated Na+ channels in cellular migration: regulation of central nervous system development and potentiation of invasive cancersReduced Na(+) and higher K(+) channel expression and function contribute to right ventricular origin of arrhythmias in Scn5a+/- mice.
P2860
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P2860
Sodium channels as macromolecular complexes: implications for inherited arrhythmia syndromes.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Sodium channels as macromolecu ...... nherited arrhythmia syndromes.
@ast
Sodium channels as macromolecu ...... nherited arrhythmia syndromes.
@en
type
label
Sodium channels as macromolecu ...... nherited arrhythmia syndromes.
@ast
Sodium channels as macromolecu ...... nherited arrhythmia syndromes.
@en
prefLabel
Sodium channels as macromolecu ...... nherited arrhythmia syndromes.
@ast
Sodium channels as macromolecu ...... nherited arrhythmia syndromes.
@en
P1476
Sodium channels as macromolecu ...... nherited arrhythmia syndromes.
@en
P2093
P304
P356
10.1016/J.CARDIORES.2005.04.003
P577
2005-08-01T00:00:00Z