Anti-obesity efficacy of LH-21, a cannabinoid CB(1) receptor antagonist with poor brain penetration, in diet-induced obese rats.
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Pharmacological Blockade of Cannabinoid CB1 Receptors in Diet-Induced Obesity Regulates Mitochondrial Dihydrolipoamide Dehydrogenase in MuscleThe cannabinoid ligand LH-21 reduces anxiety and improves glucose handling in diet-induced obese pre-diabetic mice.Ghrelin-induced orexigenic effect in rats depends on the metabolic status and is counteracted by peripheral CB1 receptor antagonism.Effects of Adolescent Intermittent Alcohol Exposure on the Expression of Endocannabinoid Signaling-Related Proteins in the Spleen of Young Adult Rats.Elaidyl-sulfamide, an oleoylethanolamide-modelled PPARα agonist, reduces body weight gain and plasma cholesterol in rats.Exposure to a Highly Caloric Palatable Diet during the Perinatal Period Affects the Expression of the Endogenous Cannabinoid System in the Brain, Liver and Adipose Tissue of Adult Rat OffspringTATA boxes in gene transcription and poly (A) tails in mRNA stability: New perspective on the effects of berberine.Structural analogs of pyrazole and sulfonamide cannabinoids: effects on acute food intake in miceCentral nervous system biomarkers for antiobesity drug developmentOleoylethanolamide enhances β-adrenergic-mediated thermogenesis and white-to-brown adipocyte phenotype in epididymal white adipose tissue in rat.New vistas for treatment of obesity and diabetes? Endocannabinoid signalling and metabolism in the modulation of energy balance.Second generation CB1 receptor blockers and other inhibitors of peripheral endocannabinoid overactivity and the rationale of their use against metabolic disorders.The cannabinoid receptor 1 and its role in influencing peripheral metabolism.CB1 receptor blockade counters age-induced insulin resistance and metabolic dysfunctionBenzyl-1,2,4-triazoles as CB 1 Cannabinoid Receptor Ligands: Preparation and In Vitro Pharmacological Evaluation.Homology modelling of CB1 receptor and selection of potential inhibitor against Obesity.Novel Peripherally Restricted Cannabinoid 1 Receptor Selective Antagonist TXX-522 with Prominent Weight-Loss Efficacy in Diet Induced Obese Mice.Cooperative role of the glucagon-like peptide-1 receptor and β3-adrenergic-mediated signalling on fat mass reduction through the downregulation of PKA/AKT/AMPK signalling in the adipose tissue and muscle of rats.Metabolic Profiling of CB1 Neutral Antagonists.LH-21 and abnormal cannabidiol improve β-cell function in isolated human and mouse islets through GPR55-dependent and -independent signalling.Low dose naloxone attenuates the pruritic but not anorectic response to rimonabant in male rats.Effects of thymoquinone on testicular structure and sperm production in male obese rats.LH-21, A Peripheral Cannabinoid Receptor 1 Antagonist, Exerts Favorable Metabolic Modulation Including Antihypertensive Effect in KKAy Mice by Regulating Inflammatory Cytokines and Adipokines on Adipose Tissue.
P2860
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P2860
Anti-obesity efficacy of LH-21, a cannabinoid CB(1) receptor antagonist with poor brain penetration, in diet-induced obese rats.
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2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Anti-obesity efficacy of LH-21 ...... n, in diet-induced obese rats.
@ast
Anti-obesity efficacy of LH-21 ...... n, in diet-induced obese rats.
@en
type
label
Anti-obesity efficacy of LH-21 ...... n, in diet-induced obese rats.
@ast
Anti-obesity efficacy of LH-21 ...... n, in diet-induced obese rats.
@en
prefLabel
Anti-obesity efficacy of LH-21 ...... n, in diet-induced obese rats.
@ast
Anti-obesity efficacy of LH-21 ...... n, in diet-induced obese rats.
@en
P2093
P2860
P50
P921
P1476
Anti-obesity efficacy of LH-21 ...... on, in diet-induced obese rats
@en
P2093
Ana Crespillo
Carmen Reyes-Cabello
Fernando Rodríguez de Fonseca
Juan Decara
Laura Hernandez-Folgado
Margarita Vida
Mónica Alonso
Pilar Goya
Vidal Perez-Valero
P2860
P304
P356
10.1111/J.1476-5381.2011.01698.X
P407
P50
P577
2012-04-01T00:00:00Z