Cell division modulates prion accumulation in cultured cells
about
Continuous quinacrine treatment results in the formation of drug-resistant prionsGlypican-1 mediates both prion protein lipid raft association and disease isoform formationPropagation of prions causing synucleinopathies in cultured cellsCellular aspects of prion replication in vitroDiscovery of 2-aminothiazoles as potent antiprion compounds.The role of the prion protein membrane anchor in prion infection.Prion dynamics and the quest for the genetic determinant in protein-only inheritanceChemical induction of misfolded prion protein conformers in cell culture.A simple, versatile and sensitive cell-based assay for prions from various speciesPrions.Antiprion compounds that reduce PrP(Sc) levels in dividing and stationary-phase cells.A survey of antiprion compounds reveals the prevalence of non-PrP molecular targets.Insights into prion biology: integrating a protein misfolding pathway with its cellular environment.Conformational transformation and selection of synthetic prion strains.Intracerebral Infusion of Antisense Oligonucleotides Into Prion-infected Mice.Antiprion Activity of DB772 and Related Monothiophene- and Furan-Based Analogs in a Persistently Infected Ovine Microglia Culture SystemPrion infection impairs lysosomal degradation capacity by interfering with rab7 membrane attachment in neuronal cellsPrion propagation and toxicity occur in vitro with two-phase kinetics specific to strain and neuronal type.Cell-to-cell propagation of infectious cytosolic protein aggregatesSmall-ruminant lentivirus enhances PrPSc accumulation in cultured sheep microglial cells.Acute cellular uptake of abnormal prion protein is cell type and scrapie-strain independent.A specific population of abnormal prion protein aggregates is preferentially taken up by cells and disaggregated in a strain-dependent manner.Anti-PrP Mab 6D11 suppresses PrP(Sc) replication in prion infected myeloid precursor line FDC-P1/22L and in the lymphoreticular system in vivoInfectious prions accumulate to high levels in non proliferative C2C12 myotubes.A cell-biased effect of estrogen in prion infection.Prion propagation, toxicity and degradation.Life cycle of cytosolic prions.Prions Ex Vivo: What Cell Culture Models Tell Us about Infectious Proteins.Replication of prions in differentiated muscle cellsThe potential of mesenchymal stem cell in prion research.Sialylation of Glycosylphosphatidylinositol (GPI) Anchors of Mammalian Prions Is Regulated in a Host-, Tissue-, and Cell-specific MannerAlteration of cell responses to PrP(Sc) in prolonged cell culture and its effect on transmission of PrP(Sc) to neural cells.Cell Culture Methods for Screening of Prion Therapeutics.Correlation of cellular factors and differential scrapie prion permissiveness in ovine microglia.Proliferative arrest of neural cells induces prion protein synthesis, nanotube formation, and cell-to-cell contacts.Prion replication in the mammalian cytosol: Functional regions within a prion domain driving induction, propagation and inheritance.
P2860
Q21090510-27DABB8C-8195-49EB-9CD3-031857B0BB66Q21131569-ABA7909D-C6A8-42B9-9DA9-F74C459E8539Q26269822-1E339A42-5391-4578-B114-070E73EB7BD7Q27014940-A9C9C2F7-B04B-435B-9DAA-25A52F73C2E7Q33520644-3D6DA081-7255-4C18-B43B-46B6D2B3CDECQ33576039-6B9825A7-0714-4C77-9EFD-0413F4F7AEDBQ33757606-6F40D2B8-68E5-433A-9207-CF0D0CF994D0Q33796040-388CD640-6DFD-4AF5-8106-9D9F5AAD14F5Q33926922-A4EF923C-DAAF-4D78-B1CB-FD474070DA80Q34413061-23D1E6D4-ACC9-4488-B44F-414A7365C3A3Q35030768-B6B2B51A-6A6B-4067-8C97-BE8A04DE58F9Q35145020-D07D6236-2550-4F9B-A03F-98C2827C1D31Q35194908-FC6881AD-58BE-4639-92B6-4FB188EC5687Q35376718-0B4CBF34-B0DF-469F-A07A-890E3F30C643Q36053816-F0E342E3-D682-4D77-ABBC-BDC2D1209586Q36068573-C433B08A-72C7-471E-A96B-3DEADBDEB8C5Q36569559-BCC13239-7761-44D1-810F-2AC0BB3C8FB1Q36607110-2D667370-797C-44FA-95D8-45DFE38BBD7FQ36762492-A2FFC76D-F82D-4F1D-873F-73A1E80C42D7Q36933940-D906D565-9DB3-439C-8BF7-1F7A8B8A0DE2Q37039973-6C517F71-687D-4357-9A51-DFB978CA8AA2Q37252741-646C815C-04DD-4794-B86E-404A3C15DACFQ37267798-BFFD4F40-8574-4619-BC87-84955F66B4B3Q37288844-9EFFFB55-F88B-4A7C-A203-10835415DD2DQ37547427-B0804EF5-DE5A-48CE-936F-44FA38D93D77Q38021894-5D00EEAA-BC91-4533-8F71-CC51D900C716Q38136055-D99D6D29-DDE9-4651-BCA8-5A2D99A25A39Q38166717-6B26DDD8-36F0-40E6-85E5-9AD728B6866AQ38187295-737E2A1F-776A-4FF7-B08D-66538194D197Q38213991-8E6555DD-1D9C-4455-9B73-3CD887E93CCEQ38763649-4C7634F9-E7D9-4201-984A-1DB5078BDE32Q39243129-0455DAE1-FAE1-426E-9B9C-5BF769541A52Q40071064-D652EA3B-3C57-4E64-AC44-F5B7555716D5Q40103519-B1990ED1-F791-4C86-9D4B-A92642807D3FQ41965706-4CD169BB-5621-469F-8637-4F93838CFC24Q54203718-3F94165B-2C0A-47F3-B1DC-EAE6E8CFA93C
P2860
Cell division modulates prion accumulation in cultured cells
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Cell division modulates prion accumulation in cultured cells
@ast
Cell division modulates prion accumulation in cultured cells
@en
type
label
Cell division modulates prion accumulation in cultured cells
@ast
Cell division modulates prion accumulation in cultured cells
@en
prefLabel
Cell division modulates prion accumulation in cultured cells
@ast
Cell division modulates prion accumulation in cultured cells
@en
P2093
P2860
P356
P1476
Cell division modulates prion accumulation in cultured cells
@en
P2093
Barnaby C H May
Beth Perkins
Julie Ullman
Puay-Wah Phuan
Sina Ghaemmaghami
P2860
P304
17971-17976
P356
10.1073/PNAS.0708372104
P407
P577
2007-11-07T00:00:00Z