Long-term, efficient inhibition of microRNA function in mice using rAAV vectors. - Wikidata - awgldk - TriplyDB

Long-term, efficient inhibition of microRNA function in mice using rAAV vectors.

Long-term, efficient inhibition of microRNA function in mice using rAAV vectors.

http://www.wikidata.org/entity/Q36169589

about

Tiny giants of gene regulation: experimental strategies for microRNA functional studies MicroRNAs and Growth Factors: An Alliance Propelling Tumor Progression MicroRNAs as pharmacological targets in diabetes miR-122 is a unique molecule with great potential in diagnosis, prognosis of liver disease, and therapy both as miRNA mimic and antimir Adeno-associated virus-mediated microRNA delivery and therapeutics Current status of miRNA-targeting therapeutics and preclinical studies against gastroenterological carcinoma Liver-targeted gene therapy: Approaches and challenges MicroRNAs as potential target in human bone and soft tissue sarcoma therapeutics MicroRNA-214 Is Upregulated in Heart Failure Patients and Suppresses XBP1-Mediated Endothelial Cells Angiogenesis Functional ectopic neuritogenesis by retinal rod bipolar cells is regulated by miR-125b-5p during retinal remodeling in RCS rats RISC-interacting clearing 3'- 5' exoribonucleases (RICEs) degrade uridylated cleavage fragments to maintain functional RISC in Arabidopsis thaliana.Global CNS transduction of adult mice by intravenously delivered rAAVrh.8 and rAAVrh.10 and nonhuman primates by rAAVrh.10 MicroRNAs in liver disease MicroRNA cluster miR-17-92 regulates multiple functionally related voltage-gated potassium channels in chronic neuropathic pain.Adult-specific functions of animal microRNAs.Rectal microRNAs are perturbed in pediatric inflammatory bowel disease of the colon.Gene transfer in the liver using recombinant adeno-associated virus Exploiting microRNA regulation for genetic engineering.High-throughput assessment of microRNA activity and function using microRNA sensor and decoy libraries.Pediatric eosinophilic esophagitis is associated with changes in esophageal microRNAs.Strategies to deliver microRNAs as potential therapeutics in the treatment of cardiovascular pathology.Impact of MicroRNA Levels, Target-Site Complementarity, and Cooperativity on Competing Endogenous RNA-Regulated Gene Expression.Potent degradation of neuronal miRNAs induced by highly complementary targets.Recombinant adeno-associated virus-mediated inhibition of microRNA-21 protects mice against the lethal schistosome infection by repressing both IL-13 and transforming growth factor beta 1 pathways.MiRNA inhibition in tissue engineering and regenerative medicine.A PCR-Based Method to Construct Lentiviral Vector Expressing Double Tough Decoy for miRNA Inhibition.Uridylation of RNA Hairpins by Tailor Confines the Emergence of MicroRNAs in Drosophila Alleviation of off-target effects from vector-encoded shRNAs via codelivered RNA decoys.MicroRNAs and other non-coding RNAs as targets for anticancer drug development.The use of high-throughput sequencing methods for plant microRNA research.Tailor: a computational framework for detecting non-templated tailing of small silencing RNAs.Current perspectives on the neurobiology of drug addiction: a focus on genetics and factors regulating gene expression.Cell-free 3D scaffold with two-stage delivery of miRNA-26a to regenerate critical-sized bone defects.Approaches to manipulating microRNAs in neurogenesis.miR-320a mediates doxorubicin-induced cardiotoxicity by targeting VEGF signal pathway.Argonaute divides its RNA guide into domains with distinct functions and RNA-binding properties An integrated miRNA functional screening and target validation method for organ morphogenesis.Degradation dynamics of microRNAs revealed by a novel pulse-chase approach.RNA interference-induced hepatotoxicity results from loss of the first synthesized isoform of microRNA-122 in mice.Application of mutated miR-206 target sites enables skeletal muscle-specific silencing of transgene expression of cardiotropic AAV9 vectors.

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Long-term, efficient inhibition of microRNA function in mice using rAAV vectors.

http://www.wikidata.org/entity/Q36169589

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Long-term, efficient inhibition of microRNA function in mice using rAAV vectors.

@ast

Long-term, efficient inhibition of microRNA function in mice using rAAV vectors.

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type

label

Long-term, efficient inhibition of microRNA function in mice using rAAV vectors.

@ast

Long-term, efficient inhibition of microRNA function in mice using rAAV vectors.

@en

prefLabel

Long-term, efficient inhibition of microRNA function in mice using rAAV vectors.

@ast

Long-term, efficient inhibition of microRNA function in mice using rAAV vectors.

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Long-term, efficient inhibition of microRNA function in mice using rAAV vectors.

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Guangping Gao

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Hongwei Zhang

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Huapeng Li

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Jason K Kim

http://www.w3.org/2001/XMLSchema#string

Jennifer A Broderick

http://www.w3.org/2001/XMLSchema#string

Jun Xie

http://www.w3.org/2001/XMLSchema#string

Li Zhong

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Mengxin Li

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Qin Su

http://www.w3.org/2001/XMLSchema#string

Qing Xie

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P2860

Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing

miRBase: microRNA sequences, targets and gene nomenclature

MicroRNA targeting specificity in mammals: determinants beyond seed pairing

Downregulation of miR-122 in the rodent and human hepatocellular carcinomas

Sequence-specific inhibition of small RNA function

Prediction of mammalian microRNA targets

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

Silencing of microRNAs in vivo with 'antagomirs'

miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting

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403-409

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10.1038/NMETH.1903

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4

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9

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Stefan L Ameres

Phillip D. Zamore

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2012-03-04T00:00:00Z

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221886243

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