Designed guanidinium-rich amphipathic oligocarbonate molecular transporters complex, deliver and release siRNA in cells.
about
Screening of efficient siRNA carriers in a library of surface-engineered dendrimersFunction through synthesis-informed designCell-Penetrating, Guanidinium-Rich Oligophosphoesters: Effective and Versatile Molecular Transporters for Drug and Probe Delivery.Renaissance of Aliphatic Polycarbonates: New Techniques and Biomedical ApplicationsArginine-rich, cell penetrating peptide-anti-microRNA complexes decrease glioblastoma migration potential.Differential fates of biomolecules delivered to target cells via extracellular vesicles.Guanidinium-rich, glycerol-derived oligocarbonates: a new class of cell-penetrating molecular transporters that complex, deliver, and release siRNACellular delivery and photochemical release of a caged inositol-pyrophosphate induces PH-domain translocation in celluloToward the Ideal Synthesis and Transformative Therapies: The Roles of Step Economy and Function Oriented Synthesis.Fifteen years of cell-penetrating, guanidinium-rich molecular transporters: basic science, research tools, and clinical applicationsCharge-altering releasable transporters (CARTs) for the delivery and release of mRNA in living animalsToward the ideal synthesis and molecular function through synthesis-informed design.Degradable hybrid materials based on cationic acylhydrazone dynamic covalent polymers promote DNA complexation through multivalent interactions.Development of protein mimics for intracellular delivery.Mapping Optimal Charge Density and Length of ROMP-Based PTDMs for siRNA InternalizationOptimal Hydrophobicity in Ring-Opening Metathesis Polymerization-Based Protein Mimics Required for siRNA Internalization.Design of aromatic-containing cell-penetrating peptide mimics with structurally modified π electronicsHelical Poly(arginine) Mimics with Superior Cell-Penetrating and Molecular Transporting Properties.Development of Guanidinium-Rich Protein Mimics for Efficient siRNA Delivery into Human T Cells.Designing mimics of membrane active proteinsFast and selective ring-opening polymerizations by alkoxides and thioureas.Synthetic polypeptides: from polymer design to supramolecular assembly and biomedical application.Dual-Function Polymeric HPMA Prodrugs for the Delivery of miRNA.Photomodulation of DNA-Templated Supramolecular Assemblies.Cellular Antisense Activity of PNA-Oligo(bicycloguanidinium) Conjugates Forming Self-Assembled Nanoaggregates.Guanidinium-functionalized Interpolyelectrolyte Complexes Enable RNAi in Resistant Insect Pests.A macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset.Non-Nucleosidic Analogues of Polyaminonucleosides and Their Influence on Thermodynamic Properties of Derived Oligonucleotides.Biodegradable functional biomaterials exploiting substituted trimethylene carbonates and organocatalytic transesterificationCell-penetrating poly(disulfide)s: focus on substrate-initiated co-polymerizationProbing the importance of π-stacking interactions in DNA-templated self-assembly of bisfunctionalized guanidinium compoundsDesign and synthesis of biodegradable grafted cationic polycarbonates as broad spectrum antimicrobial agentsDelivery of Inorganic Polyphosphate into Cells Using Amphipathic Oligocarbonate Transporters
P2860
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P2860
Designed guanidinium-rich amphipathic oligocarbonate molecular transporters complex, deliver and release siRNA in cells.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Designed guanidinium-rich amph ...... er and release siRNA in cells.
@ast
Designed guanidinium-rich amph ...... er and release siRNA in cells.
@en
type
label
Designed guanidinium-rich amph ...... er and release siRNA in cells.
@ast
Designed guanidinium-rich amph ...... er and release siRNA in cells.
@en
prefLabel
Designed guanidinium-rich amph ...... er and release siRNA in cells.
@ast
Designed guanidinium-rich amph ...... er and release siRNA in cells.
@en
P2093
P2860
P356
P1476
Designed guanidinium-rich amph ...... er and release siRNA in cells.
@en
P2093
Christina B Cooley
Erika I Geihe
James L Hedrick
Jeff R Simon
Justin A Edward
Matthew K Kiesewetter
Paul A Wender
Robert M Waymouth
Robyn P Hickerson
Roger L Kaspar
P2860
P304
13171-13176
P356
10.1073/PNAS.1211361109
P407
P577
2012-07-30T00:00:00Z