N-Alkoxy derivatization of indole-3-carbinol increases the efficacy of the G1 cell cycle arrest and of I3C-specific regulation of cell cycle gene transcription and activity in human breast cancer cells.
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Phytochemicals for the Management of MelanomaIndole-3-carbinol (I3C) increases apoptosis, represses growth of cancer cells, and enhances adenovirus-mediated oncolysisMethyl jasmonate and 1-methylcyclopropene treatment effects on quinone reductase inducing activity and post-harvest quality of broccoli.The indole-3-carbinol cyclic tetrameric derivative CTet inhibits cell proliferation via overexpression of p21/CDKN1A in both estrogen receptor-positive and triple-negative breast cancer cell lines.1-Benzyl-indole-3-carbinol is a novel indole-3-carbinol derivative with significantly enhanced potency of anti-proliferative and anti-estrogenic properties in human breast cancer cells.Indole-3-carbinol and its N-alkoxy derivatives preferentially target ERα-positive breast cancer cellsBiomedical importance of indoles.Target protein interactions of indole-3-carbinol and the highly potent derivative 1-benzyl-I3C with the C-terminal domain of human elastase uncouples cell cycle arrest from apoptotic signaling.
P2860
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P2860
N-Alkoxy derivatization of indole-3-carbinol increases the efficacy of the G1 cell cycle arrest and of I3C-specific regulation of cell cycle gene transcription and activity in human breast cancer cells.
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2007 nî lūn-bûn
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2007年の論文
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2007年論文
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2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
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2007年论文
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2007年论文
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name
N-Alkoxy derivatization of ind ...... in human breast cancer cells.
@ast
N-Alkoxy derivatization of ind ...... in human breast cancer cells.
@en
type
label
N-Alkoxy derivatization of ind ...... in human breast cancer cells.
@ast
N-Alkoxy derivatization of ind ...... in human breast cancer cells.
@en
prefLabel
N-Alkoxy derivatization of ind ...... in human breast cancer cells.
@ast
N-Alkoxy derivatization of ind ...... in human breast cancer cells.
@en
P2093
P2860
P1476
N-Alkoxy derivatization of ind ...... in human breast cancer cells.
@en
P2093
Erin J Cram
Gary L Firestone
Jenny Kung
Larisa N Yudina
Leonard F Bjeldanes
Matthew A Kinseth
Richard Staub
Sarah M Jump
P2860
P304
P356
10.1016/J.BCP.2007.09.024
P407
P50
P577
2007-10-02T00:00:00Z