Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling.
about
Episodic hormone secretion: a comparison of the basis of pulsatile secretion of insulin and GnRH.Integrated perfusion and separation systems for entrainment of insulin secretion from islets of Langerhans.Islet Hypersensitivity to Glucose Is Associated With Disrupted Oscillations and Increased Impact of Proinflammatory Cytokines in Islets From Diabetes-Prone Male Mice.Slow oscillations of KATP conductance in mouse pancreatic islets provide support for electrical bursting driven by metabolic oscillations.Complex patterns of metabolic and Ca²⁺ entrainment in pancreatic islets by oscillatory glucoseDirect measurements of oscillatory glycolysis in pancreatic islet β-cells using novel fluorescence resonance energy transfer (FRET) biosensors for pyruvate kinase M2 activityA Local Counter-Regulatory Motif Modulates the Global Phase of Hormonal Oscillations.Negative feedback synchronizes islets of Langerhans.Possible role of interleukin-1β in type 2 diabetes onset and implications for anti-inflammatory therapy strategies.Comparison of the physiological relevance of systemic vs. portal insulin delivery to evaluate whole body glucose flux during an insulin clampCalcium and Metabolic Oscillations in Pancreatic Islets: Who's Driving the Bus?(*)Interpreting frequency responses to dose-conserved pulsatile input signals in simple cell signaling motifs.Measurement of the entrainment window of islets of Langerhans by microfluidic delivery of a chirped glucose waveform.The new biology of diabetes.Decreases in Gap Junction Coupling Recovers Ca2+ and Insulin Secretion in Neonatal Diabetes Mellitus, Dependent on Beta Cell Heterogeneity and NoiseGlucose Oscillations Can Activate an Endogenous Oscillator in Pancreatic IsletsType 2 Diabetes-Associated K+ Channel TALK-1 Modulates β-Cell Electrical Excitability, Second-Phase Insulin Secretion, and Glucose HomeostasisPhase modulation of insulin pulses enhances glucose regulation and enables inter-islet synchronization.Pulsatile insulin secretion, impaired glucose tolerance and type 2 diabetes.The pathogenesis of insulin resistance: integrating signaling pathways and substrate fluxCa2+ Effects on ATP Production and Consumption Have Regulatory Roles on Oscillatory Islet Activity.Low Level Pro-inflammatory Cytokines Decrease Connexin36 Gap Junction Coupling in Mouse and Human Islets through Nitric Oxide-mediated Protein Kinase Cδ.PPARα (Peroxisome Proliferator-activated Receptor α) Activation Reduces Hepatic CEACAM1 Protein Expression to Regulate Fatty Acid Oxidation during Fasting-refeeding Transition.TCF7L2 polymorphism is associated with low nitric oxide release, endothelial dysfunction and enhanced inflammatory response after myocardial infarction.CEACAM1 loss links inflammation to insulin resistance in obesity and non-alcoholic steatohepatitis (NASH).Glucose-induced inhibition of insulin secretion.Cellular communication and heterogeneity in pancreatic islet insulin secretion dynamics.Reactive oxygen and nitrogen species disturb Ca(2+) oscillations in insulin-secreting MIN6 β-cells.Loss of Hepatic CEACAM1: A Unifying Mechanism Linking Insulin Resistance to Obesity and Non-Alcoholic Fatty Liver DiseaseSpatial and temporal coordination of insulin granule exocytosis in intact human pancreatic islets.Upregulation of an inward rectifying K+ channel can rescue slow Ca2+ oscillations in K(ATP) channel deficient pancreatic islets.Human beta cell mass and function in diabetes: Recent advances in knowledge and technologies to understand disease pathogenesis.Loss of pulsatile insulin secretion: a factor in the pathogenesis of type 2 diabetes?Role of reduced β-cell mass versus impaired β-cell function in the pathogenesis of type 2 diabetes.Hyperglycaemia is associated with impaired pulsatile insulin secretion: effect of basal insulin therapy.Is hyperinsulinemia required to develop overeating-induced obesity?A mathematical model of the impact of insulin secretion dynamics on selective hepatic insulin resistance.Calcium Oscillation Frequency-Sensitive Gene Regulation and Homeostatic Compensation in Pancreatic [Formula: see text]-Cells.Age-Dependent Decline in the Coordinated [Ca2+] and Insulin Secretory Dynamics in Human Pancreatic Islets.Closing in on the Mechanisms of Pulsatile Insulin Secretion.
P2860
Q26991915-4EBD10EE-1CA9-47E6-9CA6-A9D46026D761Q27335257-CFEF9A03-F032-4D98-A709-E1879AAFFF58Q30277210-CE22B5CE-9C73-463D-9704-87DD5FE6192CQ30410343-B9C2F617-D334-4579-94DF-C46152F562FDQ30435450-0778B7D9-F735-4804-B46C-DFFE34337555Q30557315-7446ECF7-6E1D-498D-88E4-89102DA2135EQ33686356-C143031D-0BC4-4724-96CB-8DA9321B9C23Q33736608-32E2768D-BE52-4DE5-A6BA-C085C8B05F5DQ34104455-02847B3E-065E-4267-AA05-DEEE41B77C8DQ35034818-25E945FE-D45E-4AE5-97A3-800BB2F584CFQ35090753-069D2225-2080-4E08-9BF3-BB58253D06DDQ35153131-1118F7D7-FE5B-49E9-9DE0-D20170EFCC14Q36021264-4557FB57-096A-4CDD-A013-B18ED79F64DBQ36113537-E10E1788-4EF8-416D-94EC-BE1170322E5AQ36146862-537EB44B-F933-4279-8B86-6F2A670FA347Q36175986-FB639893-8D98-4BF7-AC95-1DE49E1B1A3FQ36186289-80137E1C-6D1A-494E-B70C-F9D9712FD90CQ36290356-87FCA0C8-E6D2-43CF-8878-20EF1F93CD8AQ36417824-B4D83E2B-B9A5-4AAD-ADDE-CC643B0CD603Q36430696-71C02640-EED4-4B9E-8365-495BC78376CEQ36552630-DE77752D-478E-44DD-9BE6-52E851B12E87Q36573922-07C81381-B72D-4912-A087-37A07ED3E4C5Q36778830-C1F72B44-C0C7-481C-8735-931AFE83CDB4Q36897309-51A8F9DD-BB06-46B8-B03B-50917608E7C8Q37624585-B736F3AD-82A1-4C7C-AA71-846CD68AAA4AQ38172596-5E704FFC-0B9C-43E8-9008-A304F355E9A9Q38200278-139F61BE-2822-45D7-9720-6FFF67AF0D51Q38806419-7689B561-435B-46FC-BC22-44C6CEAE6C84Q39128964-873917AB-4FD7-4A76-B11F-AE807B5E48C6Q40533059-EB7FECA0-A982-429A-AFD8-8AEF541B806AQ41324297-A6F4F952-FE26-4046-9216-EFEB4E0EDD8BQ41689680-325C3441-F289-4F5C-8526-51DB9D870839Q41893915-49CBCF7E-1306-4F12-B060-96DD970826B3Q41945969-6589B26E-1343-4406-BAFA-AE8066BDA109Q42513759-A5787710-B189-48D1-9DC8-8E1075D9BA14Q42550724-480D7762-78D7-4EA9-94CE-9A16D91CEF53Q46775808-EA301C07-C59E-4DCC-BB5B-CADD94278DD2Q47848903-AFFF4D9C-ADBD-4247-9263-B53B74A18467Q48319128-D1C8C52C-A1D1-4C3E-B0A7-33483C242017Q49791707-94725BFC-4EA9-49E0-AE19-72DF5991A7CD
P2860
Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling.
@ast
Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling.
@en
type
label
Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling.
@ast
Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling.
@en
prefLabel
Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling.
@ast
Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling.
@en
P2093
P2860
P50
P356
P1433
P1476
Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling.
@en
P2093
Aleksey V Matveyenko
David Kirakossian
David Liuwantara
Kyle D Copps
Peter C Butler
Satoshi Fujita
Tatyana Gurlo
P2860
P304
P356
10.2337/DB11-1462
P407
P577
2012-06-11T00:00:00Z