Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling. - Wikidata - awgldk - TriplyDB

Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling.

Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling.

http://www.wikidata.org/entity/Q36182573

about

Episodic hormone secretion: a comparison of the basis of pulsatile secretion of insulin and GnRH.Integrated perfusion and separation systems for entrainment of insulin secretion from islets of Langerhans.Islet Hypersensitivity to Glucose Is Associated With Disrupted Oscillations and Increased Impact of Proinflammatory Cytokines in Islets From Diabetes-Prone Male Mice.Slow oscillations of KATP conductance in mouse pancreatic islets provide support for electrical bursting driven by metabolic oscillations.Complex patterns of metabolic and Ca²⁺ entrainment in pancreatic islets by oscillatory glucose Direct measurements of oscillatory glycolysis in pancreatic islet β-cells using novel fluorescence resonance energy transfer (FRET) biosensors for pyruvate kinase M2 activity A Local Counter-Regulatory Motif Modulates the Global Phase of Hormonal Oscillations.Negative feedback synchronizes islets of Langerhans.Possible role of interleukin-1β in type 2 diabetes onset and implications for anti-inflammatory therapy strategies.Comparison of the physiological relevance of systemic vs. portal insulin delivery to evaluate whole body glucose flux during an insulin clamp Calcium and Metabolic Oscillations in Pancreatic Islets: Who's Driving the Bus?(*)Interpreting frequency responses to dose-conserved pulsatile input signals in simple cell signaling motifs.Measurement of the entrainment window of islets of Langerhans by microfluidic delivery of a chirped glucose waveform.The new biology of diabetes.Decreases in Gap Junction Coupling Recovers Ca2+ and Insulin Secretion in Neonatal Diabetes Mellitus, Dependent on Beta Cell Heterogeneity and Noise Glucose Oscillations Can Activate an Endogenous Oscillator in Pancreatic Islets Type 2 Diabetes-Associated K+ Channel TALK-1 Modulates β-Cell Electrical Excitability, Second-Phase Insulin Secretion, and Glucose Homeostasis Phase modulation of insulin pulses enhances glucose regulation and enables inter-islet synchronization.Pulsatile insulin secretion, impaired glucose tolerance and type 2 diabetes.The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux Ca2+ Effects on ATP Production and Consumption Have Regulatory Roles on Oscillatory Islet Activity.Low Level Pro-inflammatory Cytokines Decrease Connexin36 Gap Junction Coupling in Mouse and Human Islets through Nitric Oxide-mediated Protein Kinase Cδ.PPARα (Peroxisome Proliferator-activated Receptor α) Activation Reduces Hepatic CEACAM1 Protein Expression to Regulate Fatty Acid Oxidation during Fasting-refeeding Transition.TCF7L2 polymorphism is associated with low nitric oxide release, endothelial dysfunction and enhanced inflammatory response after myocardial infarction.CEACAM1 loss links inflammation to insulin resistance in obesity and non-alcoholic steatohepatitis (NASH).Glucose-induced inhibition of insulin secretion.Cellular communication and heterogeneity in pancreatic islet insulin secretion dynamics.Reactive oxygen and nitrogen species disturb Ca(2+) oscillations in insulin-secreting MIN6 β-cells.Loss of Hepatic CEACAM1: A Unifying Mechanism Linking Insulin Resistance to Obesity and Non-Alcoholic Fatty Liver Disease Spatial and temporal coordination of insulin granule exocytosis in intact human pancreatic islets.Upregulation of an inward rectifying K+ channel can rescue slow Ca2+ oscillations in K(ATP) channel deficient pancreatic islets.Human beta cell mass and function in diabetes: Recent advances in knowledge and technologies to understand disease pathogenesis.Loss of pulsatile insulin secretion: a factor in the pathogenesis of type 2 diabetes?Role of reduced β-cell mass versus impaired β-cell function in the pathogenesis of type 2 diabetes.Hyperglycaemia is associated with impaired pulsatile insulin secretion: effect of basal insulin therapy.Is hyperinsulinemia required to develop overeating-induced obesity?A mathematical model of the impact of insulin secretion dynamics on selective hepatic insulin resistance.Calcium Oscillation Frequency-Sensitive Gene Regulation and Homeostatic Compensation in Pancreatic [Formula: see text]-Cells.Age-Dependent Decline in the Coordinated [Ca2+] and Insulin Secretory Dynamics in Human Pancreatic Islets.Closing in on the Mechanisms of Pulsatile Insulin Secretion.

P2860

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P2860

Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling.

http://www.wikidata.org/entity/Q36182573

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling.

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Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling.

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type

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Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling.

@ast

Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling.

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prefLabel

Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling.

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Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling.

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Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling.

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Aleksey V Matveyenko

http://www.w3.org/2001/XMLSchema#string

David Kirakossian

http://www.w3.org/2001/XMLSchema#string

David Liuwantara

http://www.w3.org/2001/XMLSchema#string

Kyle D Copps

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Peter C Butler

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Satoshi Fujita

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Tatyana Gurlo

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P2860

Impaired hepatic glycogen synthesis in glucokinase-deficient (MODY-2) subjects

Insulin degradation: progress and potential

FoxO1 mediates insulin-dependent regulation of hepatic VLDL production in mice

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

Inhibition of Foxo1 function is associated with improved fasting glycemia in diabetic mice

Insulin resistance-related factors, but not glycemia, predict coronary artery disease in type 1 diabetes: 10-year follow-up data from the Pittsburgh Epidemiology of Diabetes Complications Study.

Insulin resistance and cardiovascular disease.

Hepatic FoxO1 ablation exacerbates lipid abnormalities during hyperglycemia

Impaired net hepatic glycogen synthesis in insulin-dependent diabetic subjects during mixed meal ingestion. A 13C nuclear magnetic resonance spectroscopy study.

Pathogenesis of fasting and postprandial hyperglycemia in type 2 diabetes: implications for therapy.

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2269-2279

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10.2337/DB11-1462

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9

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61

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Claudio Cobelli

Chiara Dalla Man

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2012-06-11T00:00:00Z

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225296231

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22688333

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3425431

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