Regioselective glucuronidation of flavonols by six human UGT1A isoforms.
about
Evaluation of 3,3',4'-trihydroxyflavone and 3,6,4'-trihydroxyflavone (4'-O-glucuronidation) as the in vitro functional markers for hepatic UGT1A1.Accurate prediction of glucuronidation of structurally diverse phenolics by human UGT1A9 using combined experimental and in silico approaches.Regioselective sulfation and glucuronidation of phenolics: insights into the structural basis.Regiospecificity of human UDP-glucuronosyltransferase isoforms in chalcone and flavanone glucuronidation determined by metal complexation and tandem mass spectrometry.A new strategy to rapidly evaluate kinetics of glucuronide efflux by breast cancer resistance protein (BCRP/ABCG2).Mutual regioselective inhibition of human UGT1A1-mediated glucuronidation of four flavonoidsDisposition of flavonoids via recycling: Direct biliary excretion of enterically or extrahepatically derived flavonoid glucuronides.Substrate inhibition kinetics in drug metabolism reactions.Understanding substrate selectivity of human UDP-glucuronosyltransferases through QSAR modeling and analysis of homologous enzymes.Transcriptional regulation of human UDP-glucuronosyltransferase genes.Flavonoid interactions during digestion, absorption, distribution and metabolism: a sequential structure-activity/property relationship-based approach in the study of bioavailability and bioactivity.Identification of flavone glucuronide isomers by metal complexation and tandem mass spectrometry: regioselectivity of uridine 5'-diphosphate-glucuronosyltransferase isozymes in the biotransformation of flavones.Glucuronidation of capsaicin by liver microsomes and expressed UGT enzymes: reaction kinetics, contribution of individual enzymes and marked species differences.3D-QSAR studies on UDP-glucuronosyltransferase 2B7 substrates using the pharmacophore and VolSurf approaches.Glucuronidation of macelignan by human liver microsomes and expressed UGT enzymes: identification of UGT1A1 and 2B7 as the main contributing enzymes.
P2860
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P2860
Regioselective glucuronidation of flavonols by six human UGT1A isoforms.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Regioselective glucuronidation of flavonols by six human UGT1A isoforms.
@ast
Regioselective glucuronidation of flavonols by six human UGT1A isoforms.
@en
type
label
Regioselective glucuronidation of flavonols by six human UGT1A isoforms.
@ast
Regioselective glucuronidation of flavonols by six human UGT1A isoforms.
@en
prefLabel
Regioselective glucuronidation of flavonols by six human UGT1A isoforms.
@ast
Regioselective glucuronidation of flavonols by six human UGT1A isoforms.
@en
P2093
P2860
P1476
Regioselective glucuronidation of flavonols by six human UGT1A isoforms.
@en
P2093
P2860
P304
P356
10.1007/S11095-011-0418-5
P577
2011-04-07T00:00:00Z