Tuning of EAG K(+) channel inactivation: molecular determinants of amplification by mutations and a small molecule
about
Calmodulin Regulates Human Ether à Go-Go 1 (hEAG1) Potassium Channels through Interactions of the Eag Domain with the Cyclic Nucleotide Binding Homology DomainTwo outward potassium current types are expressed during the neural differentiation of neural stem cellsThe Eag domain regulates the voltage-dependent inactivation of rat Eag1 K+ channels.ICA-105574 interacts with a common binding site to elicit opposite effects on inactivation gating of EAG and ERG potassium channels.Structural basis of ion permeation gating in Slo2.1 K+ channels.HERG1 channel agonists and cardiac arrhythmia.Mutations in KCNH1 and ATP6V1B2 cause Zimmermann-Laband syndrome.Ginsenoside Rg3, a Gating Modifier of EAG Family K+ Channels.The intrinsically liganded cyclic nucleotide-binding homology domain promotes KCNH channel activation.Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy.Molecular Basis of Altered hERG1 Channel Gating Induced by Ginsenoside Rg3.Inhibition of the K+ conductance and Cole-Moore shift of the oncogenic Kv10.1 channel by amiodarone.Gating Modulation of the Tumor-Related Kv10.1 Channel by Mibefradil.Diminished hERG K+ channel activity facilitates strong human labour contractions but is dysregulated in obese women
P2860
Q28119193-034F18CB-4486-405D-A409-13DE8B99B334Q34095139-750FFB6A-BED2-45AD-A082-850817D611B4Q34379526-CD18E081-44B8-4B2C-8091-054FE614045BQ36717056-1AA22804-0392-49BD-81E4-C121E67D2C07Q37268772-844AD4D1-CB4D-4C8D-B3DD-74DB9FE1074AQ37699209-AAC75736-6368-4047-B0E6-AACA5754FC51Q41010224-A6BD4DC9-AF04-4247-ADD5-1C3E8F711E3DQ41653882-58C131D1-4D51-4DCD-8595-B5C98B6A4D2BQ42322794-D5A7F738-586A-4737-9219-C0FB7AA9543FQ46125040-58280FF8-FBE5-4226-836C-21CB59824C24Q48517340-771BF714-325E-4713-88A7-9D12DDD74B49Q50017733-4C2910E4-FDE3-4F7C-9CEC-5A85A5561006Q51723775-1645EAAD-9404-4F00-861A-71AA1B51C279Q57669880-3C89D554-6BFF-45A8-BC9F-45C6F49359D5
P2860
Tuning of EAG K(+) channel inactivation: molecular determinants of amplification by mutations and a small molecule
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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name
Tuning of EAG K(+) channel ina ...... mutations and a small molecule
@ast
Tuning of EAG K(+) channel ina ...... mutations and a small molecule
@en
type
label
Tuning of EAG K(+) channel ina ...... mutations and a small molecule
@ast
Tuning of EAG K(+) channel ina ...... mutations and a small molecule
@en
prefLabel
Tuning of EAG K(+) channel ina ...... mutations and a small molecule
@ast
Tuning of EAG K(+) channel ina ...... mutations and a small molecule
@en
P2860
P356
P1476
Tuning of EAG K(+) channel ina ...... mutations and a small molecule
@en
P2093
Michael C Sanguinetti
Vivek Garg
P2860
P304
P356
10.1085/JGP.201210826
P577
2012-09-01T00:00:00Z