Voltage-dependent inactivation of the human K+ channel KvLQT1 is eliminated by association with minimal K+ channel (minK) subunits
about
Molecular cloning and functional expression of KCNQ5, a potassium channel subunit that may contribute to neuronal M-current diversityInteraction of KCNE subunits with the KCNQ1 K+ channel poreFunctional and clinical characterization of KCNJ2 mutations associated with LQT7 (Andersen syndrome)Inactivation as a new regulatory mechanism for neuronal Kv7 channelsDriving with no brakes: molecular pathophysiology of Kv7 potassium channelsKCNQ5, a novel potassium channel broadly expressed in brain, mediates M-type currentsStructural basis of slow activation gating in the cardiac I Ks channel complexIKs channels open slowly because KCNE1 accessory subunits slow the movement of S4 voltage sensors in KCNQ1 pore-forming subunitsRate dependency of delayed rectifier currents during the guinea-pig ventricular action potentialTwo open states and rate-limiting gating steps revealed by intracellular Na+ block of human KCNQ1 and KCNQ1/KCNE1 K+ channelsA kinetic study on the stereospecific inhibition of KCNQ1 and I(Ks) by the chromanol 293BInhibition of HERG potassium channels by celecoxib and its mechanismSexual dimorphism and oestrogen regulation of KCNE3 expression modulates the functional properties of KCNQ1 K⁺ channelsKCNE1 induces fenestration in the Kv7.1/KCNE1 channel complex that allows for highly specific pharmacological targetingStructural correlates of selectivity and inactivation in potassium channels.Characterization of KCNQ1 atrial fibrillation mutations reveals distinct dependence on KCNE1.Novel Kv7.1-phosphatidylinositol 4,5-bisphosphate interaction sites uncovered by charge neutralization scanningA computational model of the human left-ventricular epicardial myocyte.Mechanisms and determinants of ultralong action potential duration and slow rate-dependence in cardiac myocytes.Allosteric features of KCNQ1 gating revealed by alanine scanning mutagenesis.Computational model of vectorial potassium transport by cochlear marginal cells and vestibular dark cells.Computational modeling reveals key contributions of KCNQ and hERG currents to the malleability of uterine action potentials underpinning labor.Extracellular potassium inhibits Kv7.1 potassium channels by stabilizing an inactivated state.Domain-domain interactions determine the gating, permeation, pharmacology, and subunit modulation of the IKs ion channelKCNQ1 subdomains involved in KCNE modulation revealed by an invertebrate KCNQ1 orthologue.Electrophysiological and functional effects of the KCNQ channel blocker XE991 on murine portal vein smooth muscle cells.Subunit interaction determines IKs participation in cardiac repolarization and repolarization reserveModelling and imaging cardiac repolarization abnormalities.Regulation of Voltage-Activated K(+) Channel Gating by Transmembrane β Subunits.Computational biology in the study of cardiac ion channels and cell electrophysiology.An inactivation gate in the selectivity filter of KCNQ1 potassium channels.Tuning of EAG K(+) channel inactivation: molecular determinants of amplification by mutations and a small moleculePhosphatidylinositol-4,5-bisphosphate, PIP2, controls KCNQ1/KCNE1 voltage-gated potassium channels: a functional homology between voltage-gated and inward rectifier K+ channels.External barium affects the gating of KCNQ1 potassium channels and produces a pore block via two discrete sitesMinK subdomains that mediate modulation of and association with KvLQT1.Probing the structural basis for differential KCNQ1 modulation by KCNE1 and KCNE2KCNQ1 and KCNE1 in the IKs channel complex make state-dependent contacts in their extracellular domains.Voltage-dependent C-type inactivation in a constitutively open K+ channelDynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels.Early afterdepolarizations in cardiac myocytes: beyond reduced repolarization reserve
P2860
Q22254006-F863E509-36C2-402D-982C-74A1CD267DBFQ24548322-B29E2961-73B4-4933-A7A2-9914D83D9BA4Q24553132-C0082CB4-E1F7-4FEC-9EF2-4F5DC2CAC95CQ24676507-D4440968-11DE-4CF8-922E-E45AADE48D06Q27023978-0D72D08E-E893-4103-B63B-DA821204EFB8Q28144661-BD1BF85D-9F01-424A-8CC4-54F60B7B0450Q28241288-2ED8471A-F5E8-471F-88F9-276A02EC21D8Q28284500-2BA8EB84-4723-4222-AF1F-E8F2075DDB49Q28345142-A142593A-F1C6-470F-BF78-88C70F32D875Q28364994-A3140646-08FB-4975-960B-58C8955DB255Q28366030-9CF67E7C-3C33-45B6-95CF-4E3895B0EB34Q28477588-E5C2068C-23C2-4B43-9F01-D8049A5D9AE0Q28568421-0D2A66EE-421E-46FA-AD36-16FB16AAAF5CQ28822031-6CB76AF0-CEF5-491E-9E5F-400C1F9F4BF6Q30407608-792514DF-10AB-41DB-A26F-47F9F3886D1EQ30411829-89F00B9B-4040-410A-9E56-EE649F756AACQ34044611-0BDED4E5-7F4C-48E7-AF72-FAD2B372550CQ34186985-D60AB9DC-6309-4328-B6AF-474B3C6A07A9Q34405346-C3433A43-4014-4C02-B5D9-79958D6DD9E0Q34568142-4DB7411C-BDA2-461D-96E0-A753A71CD320Q34569353-9C78BDD5-C9E7-4530-82AD-96541CD946EEQ34634464-E1E76EE3-74F9-4E8B-921D-6A9DAE86DE7FQ35218318-F69192EB-77E2-43D1-B298-673F2EC0B6D0Q35240329-A41A0C82-D54B-4297-ABEA-C778576BF20BQ35503231-D8E1D341-96F4-4DBD-B9D0-4CB0B4229B06Q35545042-FCA7F8D0-02D0-4C22-BFC0-95F59BAB2A90Q35676902-CA17C484-4315-4467-820F-E42C49EBA6F2Q35783131-3913C655-1869-4243-A481-CE5E4E9FF8A0Q35893721-37288A58-2801-4847-8140-481D6B0D8FBAQ36015209-6FDA2234-2C68-4208-9BFE-99E5ABF1CC28Q36175957-1FC5DB9F-9EBE-4764-8F3C-E6B7D4EB9E57Q36209596-396C8395-10C3-4401-A3E3-6E5C520DC9D3Q36266824-7A068F54-2787-4A2B-817D-BF83797DD58EQ36436699-D4437D46-D52D-426D-A704-9E26138B0EDAQ36444720-AAA5B91A-5E96-495A-A9E1-00837442792AQ36446422-91282526-6DEE-4E7B-8629-72919B902EACQ36667897-3B8934C8-98C5-445E-B26C-B030CEA40E4EQ36856367-F2311E25-3100-4F92-92A2-D3068D892F6FQ36884182-9E36FDFC-66E1-41CD-8888-9793AEFEAD9BQ36943422-84BDFB7A-5429-46EF-A01C-F9E799057B24
P2860
Voltage-dependent inactivation of the human K+ channel KvLQT1 is eliminated by association with minimal K+ channel (minK) subunits
description
1998 nî lūn-bûn
@nan
1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Voltage-dependent inactivation ...... mal K+ channel (minK) subunits
@ast
Voltage-dependent inactivation ...... mal K+ channel (minK) subunits
@en
Voltage-dependent inactivation ...... mal K+ channel (minK) subunits
@nl
type
label
Voltage-dependent inactivation ...... mal K+ channel (minK) subunits
@ast
Voltage-dependent inactivation ...... mal K+ channel (minK) subunits
@en
Voltage-dependent inactivation ...... mal K+ channel (minK) subunits
@nl
prefLabel
Voltage-dependent inactivation ...... mal K+ channel (minK) subunits
@ast
Voltage-dependent inactivation ...... mal K+ channel (minK) subunits
@en
Voltage-dependent inactivation ...... mal K+ channel (minK) subunits
@nl
P2860
P3181
P1476
Voltage-dependent inactivation ...... mal K+ channel (minK) subunits
@en
P2093
M C Sanguinetti
M Tristani-Firouzi
P2860
P3181
P356
10.1111/J.1469-7793.1998.037BZ.X
P407
P478
510 ( Pt 1)
P577
1998-07-01T00:00:00Z