Glucocorticoid resistance in chronic lymphocytic leukaemia is associated with a failure of upregulated Bim/Bcl-2 complexes to activate Bax and Bak.
about
Regulation of Bim in Health and DiseaseSelective glucocorticoid receptor-activating adjuvant therapy in cancer treatmentsBEX1 promotes imatinib-induced apoptosis by binding to and antagonizing BCL-2Lack of association between Bax promoter (-248G>A) single nucleotide polymorphism and susceptibility towards cancer: evidence from a meta-analysis.MicroRNAs and Glucocorticoid-Induced Apoptosis in Lymphoid MalignanciesSerum amyloid A inhibits dendritic cell apoptosis to induce glucocorticoid resistance in CD4(+) T cells.Selective IAP inhibition results in sensitization of unstimulated but not CD40-stimulated chronic lymphocytic leukaemia cells to TRAIL-induced apoptosis.The investigational agent MLN2238 induces apoptosis and is cytotoxic to CLL cells in vitro, as a single agent and in combination with other drugs.Delineating the distinct role of AKT in mediating cell survival and proliferation induced by CD154 and IL-4/IL-21 in chronic lymphocytic leukemia.Lck is a relevant target in chronic lymphocytic leukaemia cells whose expression variance is unrelated to disease outcome.
P2860
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P2860
Glucocorticoid resistance in chronic lymphocytic leukaemia is associated with a failure of upregulated Bim/Bcl-2 complexes to activate Bax and Bak.
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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name
Glucocorticoid resistance in c ...... lexes to activate Bax and Bak.
@ast
Glucocorticoid resistance in c ...... lexes to activate Bax and Bak.
@en
type
label
Glucocorticoid resistance in c ...... lexes to activate Bax and Bak.
@ast
Glucocorticoid resistance in c ...... lexes to activate Bax and Bak.
@en
prefLabel
Glucocorticoid resistance in c ...... lexes to activate Bax and Bak.
@ast
Glucocorticoid resistance in c ...... lexes to activate Bax and Bak.
@en
P2093
P2860
P356
P1476
Glucocorticoid resistance in c ...... plexes to activate Bax and Bak
@en
P2093
A G Bosanquet
A R Pettitt
N Rockliffe
T Melarangi
P2860
P356
10.1038/CDDIS.2012.102
P577
2012-08-16T00:00:00Z