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Crystal structure of the yeast TSC1 core domain and implications for tuberous sclerosis pathological mutationsDiacylglycerol Kinases in T Cell Tolerance and Effector FunctionTsc1 promotes the differentiation of memory CD8+ T cells via orchestrating the transcriptional and metabolic programsIndoleamine 2,3-dioxygenase pathways of pathogenic inflammation and immune escape in cancerTSC1 Promotes B Cell Maturation but Is Dispensable for Germinal Center FormationmTORC1 in Thymic Epithelial Cells Is Critical for Thymopoiesis, T-Cell Generation, and Temporal Control of γδT17 Development and TCRγ/δ RecombinationMnk1 and 2 are dispensable for T cell development and activation but important for the pathogenesis of experimental autoimmune encephalomyelitis.Expression of CD39 on Activated T Cells Impairs their Survival in Older Individuals.Critical role of the tumor suppressor tuberous sclerosis complex 1 in dendritic cell activation of CD4 T cells by promoting MHC class II expression via IRF4 and CIITA.mTORC2 in Thymic Epithelial Cells Controls Thymopoiesis and T Cell Development.T cell Receptor Signal Transduction in T lymphocytes.NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activationmTORC1-Activated Monocytes Increase Tregs and Inhibit the Immune Response to Bacterial Infections.mTOR is critical for intestinal T-cell homeostasis and resistance to Citrobacter rodentium.Critical roles of mTOR Complex 1 and 2 for T follicular helper cell differentiation and germinal center responses.mTOR and metabolic pathways in T cell quiescence and functional activation.TSC1 regulates the balance between effector and regulatory T cells.Mechanistic target of rapamycin complex 1 is critical for invariant natural killer T-cell development and effector function.Tuberous sclerosis 1 promotes invariant NKT cell anergy and inhibits invariant NKT cell-mediated antitumor immunity.iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions.Induction and stability of the anergic phenotype in T cellsRapamycin-resistant effector T-cell therapy.mTOR and its tight regulation for iNKT cell development and effector function.An expanded role of the tumor suppressor TSC1 in T cell toleranceEssential Role of mTORC1 in Self-Renewal of Murine Alveolar Macrophages.Discovery of IDO1 Inhibitors: From Bench to Bedside.Targeting the IDO1 pathway in cancer: from bench to bedside
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Tumor suppressor TSC1 is critical for T-cell anergy
@ast
Tumor suppressor TSC1 is critical for T-cell anergy
@en
type
label
Tumor suppressor TSC1 is critical for T-cell anergy
@ast
Tumor suppressor TSC1 is critical for T-cell anergy
@en
prefLabel
Tumor suppressor TSC1 is critical for T-cell anergy
@ast
Tumor suppressor TSC1 is critical for T-cell anergy
@en
P2093
P2860
P356
P1476
Tumor suppressor TSC1 is critical for T-cell anergy
@en
P2093
Dan-Li Xie
Jinhong Wu
Xiao-Ping Zhong
Yong-Liang Lou
P2860
P304
14152-14157
P356
10.1073/PNAS.1119744109
P407
P577
2012-08-13T00:00:00Z