Association of GAD-65, but not of GAD-67, with the Golgi complex of transfected Chinese hamster ovary cells mediated by the N-terminal region.
about
betaIV spectrin, a new spectrin localized at axon initial segments and nodes of ranvier in the central and peripheral nervous systemDistinct protein forms are produced from alternatively spliced bicistronic glutamic acid decarboxylase mRNAs during developmentGERp95, a membrane-associated protein that belongs to a family of proteins involved in stem cell differentiationrbSec1A and B colocalize with syntaxin 1 and SNAP-25 throughout the axon, but are not in a stable complex with syntaxinThe synaptic vesicle-associated protein amphiphysin is the 128-kD autoantigen of Stiff-Man syndrome with breast cancerAutoimmune stiff person syndrome and related myelopathies: understanding of electrophysiological and immunological processes.Amino acid residues 24-31 but not palmitoylation of cysteines 30 and 45 are required for membrane anchoring of glutamic acid decarboxylase, GAD65Targeting of the 67-kDa isoform of glutamic acid decarboxylase to intracellular organelles is mediated by its interaction with the NH2-terminal region of the 65-kDa isoform of glutamic acid decarboxylaseTwo distinct mechanisms target GAD67 to vesicular pathways and presynaptic clustersDemonstration of functional coupling between gamma -aminobutyric acid (GABA) synthesis and vesicular GABA transport into synaptic vesiclesHeterogeneity of the supramammillary-hippocampal pathways: evidence for a unique GABAergic neurotransmitter phenotype and regional differences.A membrane form of brain L-glutamate decarboxylase: identification, isolation, and its relation to insulin-dependent mellitus.Autoimmunity to beta IV spectrin in paraneoplastic lower motor neuron syndromeMotifs and structural fold of the cofactor binding site of human glutamate decarboxylasePalmitoylation and trafficking of GAD65 are impaired in a cellular model of Huntington's disease.Widespread expression of an autoantigen-GAD65 transgene does not tolerize non-obese diabetic mice and can exacerbate diseaseA combination of three distinct trafficking signals mediates axonal targeting and presynaptic clustering of GAD65GAD-reactive CD4+ Th1 cells induce diabetes in NOD/SCID mice.GABA(A) receptor and glycine receptor activation by paracrine/autocrine release of endogenous agonists: more than a simple communication pathway.Advances in the cellular immunological pathogenesis of type 1 diabetesGAD, diabetes, and Stiff-Man syndrome: some progress and more questions.The hydrophilic isoform of glutamate decarboxylase, GAD67, is targeted to membranes and nerve terminals independent of dimerization with the hydrophobic membrane-anchored isoform, GAD65.A signal located within amino acids 1-27 of GAD65 is required for its targeting to the Golgi complex region.Identification of a dominant epitope of glutamic acid decarboxylase (GAD-65) recognized by autoantibodies in stiff-man syndromeA Role for GAT-1 in Presynaptic GABA Homeostasis?Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons.Binocular pattern deprivation interferes with the expression of proteins involved in primary visual cortex maturation in the cat.Preservation of enzyme activity and antigenicity after mutagenesis of the membrane anchoring domain of GAD65.Post-translational modifications of ICA512, a receptor tyrosine phosphatase-like protein of secretory granules.Non-synaptic localization of the glutamate transporter EAAC1 in cultured hippocampal neurons.Detection and immunochemical characterization of glutamic acid decarboxylase autoantibodies in patients with autoimmune diabetes mellitus.
P2860
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P2860
Association of GAD-65, but not of GAD-67, with the Golgi complex of transfected Chinese hamster ovary cells mediated by the N-terminal region.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Association of GAD-65, but not ...... ated by the N-terminal region.
@ast
Association of GAD-65, but not ...... ated by the N-terminal region.
@en
type
label
Association of GAD-65, but not ...... ated by the N-terminal region.
@ast
Association of GAD-65, but not ...... ated by the N-terminal region.
@en
prefLabel
Association of GAD-65, but not ...... ated by the N-terminal region.
@ast
Association of GAD-65, but not ...... ated by the N-terminal region.
@en
P2093
P2860
P356
P1476
Association of GAD-65, but not ...... ated by the N-terminal region.
@en
P2093
D Aggujaro
M Solimena
P De Camilli
P2860
P304
P356
10.1073/PNAS.90.7.3073
P407
P577
1993-04-01T00:00:00Z