PIP2 controls voltage-sensor movement and pore opening of Kv channels through the S4-S5 linker.
about
Membrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory.Regulation of KCNQ/Kv7 family voltage-gated K+ channels by lipids.Fitting K(V) potassium channels into the PIP(2) puzzle: Hille group connects dots between illustrious HH groups.The phosphoinositide sensitivity of the K(v) channel family.Structural determinants of phosphatidylinositol 4,5-bisphosphate (PIP2) regulation of BK channel activity through the RCK1 Ca2+ coordination site.PIP₂-dependent coupling is prominent in Kv7.1 due to weakened interactions between S4-S5 and S6.Probing binding sites and mechanisms of action of an I(Ks) activator by computations and experiments.A long QT mutation substitutes cholesterol for phosphatidylinositol-4,5-bisphosphate in KCNQ1 channel regulation.Phosphoinositides regulate ion channels.Phosphoinositide control of membrane protein function: a frontier led by studies on ion channels.Functional Characterization of Cnidarian HCN Channels Points to an Early Evolution of Ih.Migration of PIP2 lipids on voltage-gated potassium channel surface influences channel deactivationBimodal regulation of an Elk subfamily K+ channel by phosphatidylinositol 4,5-bisphosphate.The cytosolic GH loop regulates the phosphatidylinositol 4,5-bisphosphate-induced gating kinetics of Kir2 channels.Two structural components in CNGA3 support regulation of cone CNG channels by phosphoinositides.Phosphatidylinositol 4,5-bisphosphate alters pharmacological selectivity for epilepsy-causing KCNQ potassium channelsA molecular determinant of phosphoinositide affinity in mammalian TRPV channels.S3-S4 linker length modulates the relaxed state of a voltage-gated potassium channelStructural Basis for Differences in Dynamics Induced by Leu Versus Ile Residues in the CD Loop of Kir ChannelsDynamic PIP2 interactions with voltage sensor elements contribute to KCNQ2 channel gatingLipid bilayer modules as determinants of K+ channel gating.PIP2 regulation of KCNQ channels: biophysical and molecular mechanisms for lipid modulation of voltage-dependent gating.Voltage-Dependent Gating: Novel Insights from KCNQ1 Channels.The where and how of PIP regulation of cone photoreceptor CNG channels.Three pairs of weak interactions precisely regulate the G-loop gate of Kir2.1 channel.Simulation-based prediction of phosphatidylinositol 4,5-bisphosphate binding to an ion channel.Contrasting effects of phosphatidylinositol 4,5-bisphosphate on cloned TMEM16A and TMEM16B channels.Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7.2 potassium channels to phosphatidylinositol 4,5-bisphosphate.Dual effect of phosphatidylinositol (4,5)-bisphosphate PIP(2) on Shaker K(+) [corrected] channelsDual Regulation of Voltage-Sensitive Ion Channels by PIP(2).Regulation of Kv2.1 channel inactivation by phosphatidylinositol 4,5-bisphosphate.The Effects of 4-Hydroxybenzoic Acid Identified from Bamboo (Dendrocalamus asper) Shoots on Kv1.4 Channel.
P2860
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P2860
PIP2 controls voltage-sensor movement and pore opening of Kv channels through the S4-S5 linker.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
PIP2 controls voltage-sensor m ...... nels through the S4-S5 linker.
@ast
PIP2 controls voltage-sensor m ...... nels through the S4-S5 linker.
@en
type
label
PIP2 controls voltage-sensor m ...... nels through the S4-S5 linker.
@ast
PIP2 controls voltage-sensor m ...... nels through the S4-S5 linker.
@en
prefLabel
PIP2 controls voltage-sensor m ...... nels through the S4-S5 linker.
@ast
PIP2 controls voltage-sensor m ...... nels through the S4-S5 linker.
@en
P2093
P2860
P356
P1476
PIP2 controls voltage-sensor m ...... nels through the S4-S5 linker.
@en
P2093
Aldo A Rodriguez-Menchaca
Avia Rosenhouse-Dantsker
Diomedes E Logothetis
Qiong-Yao Tang
Scott K Adney
Xuan-Yu Meng
P2860
P304
P356
10.1073/PNAS.1207901109
P407
P577
2012-08-13T00:00:00Z