Mutations in the SAC1 gene suppress defects in yeast Golgi and yeast actin function
about
Novel members of the human oxysterol-binding protein family bind phospholipids and regulate vesicle transportThe human phosphatidylinositol phosphatase SAC1 interacts with the coatomer I complexThe Phox homology (PX) domain, a new player in phosphoinositide signallingRecruitment of an alternatively spliced form of synaptojanin 2 to mitochondria by the interaction with the PDZ domain of a mitochondrial outer membrane protein.Characterization of TPM1 disrupted yeast cells indicates an involvement of tropomyosin in directed vesicular transportThe SAC domain-containing protein gene family in ArabidopsisPheromone-regulated genes required for yeast mating differentiationPhosphoinositides: tiny lipids with giant impact on cell regulationGolgi membrane dynamics and lipid metabolismIdentification of Phosphoinositide-Binding Protein PATELLIN2 as a Substrate of Arabidopsis MPK4 MAP Kinase during Septum Formation in Cytokinesis.Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase functionResurrection of a functional phosphatidylinositol transfer protein from a pseudo-Sec14 scaffold by directed evolutionCrystal structure of the Saccharomyces cerevisiae phosphatidylinositol-transfer proteinLocal control of phosphatidylinositol 4-phosphate signaling in the Golgi apparatus by Vps74 and Sac1 phosphoinositide phosphataseSac1 lipid phosphatase and Stt4 phosphatidylinositol 4-kinase regulate a pool of phosphatidylinositol 4-phosphate that functions in the control of the actin cytoskeleton and vacuole morphology.Allosteric activation of the phosphoinositide phosphatase Sac1 by anionic phospholipids.Cessation of growth to prevent cell death due to inhibition of phosphatidylcholine synthesis is impaired at 37 degrees C in Saccharomyces cerevisiae.Trans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast.INP51, a yeast inositol polyphosphate 5-phosphatase required for phosphatidylinositol 4,5-bisphosphate homeostasis and whose absence confers a cold-resistant phenotype.Pleiotropic alterations in lipid metabolism in yeast sac1 mutants: relationship to "bypass Sec14p" and inositol auxotrophy.DNA sequencing and analysis of 130 kb from yeast chromosome XV.SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases.Identification of a novel family of nonclassic yeast phosphatidylinositol transfer proteins whose function modulates phospholipase D activity and Sec14p-independent cell growth.The yeast inositol polyphosphate 5-phosphatases inp52p and inp53p translocate to actin patches following hyperosmotic stress: mechanism for regulating phosphatidylinositol 4,5-bisphosphate at plasma membrane invaginations.Retention of the yeast Sac1p phosphatase in the endoplasmic reticulum causes distinct changes in cellular phosphoinositide levels and stimulates microsomal ATP transport.The Saccharomyces cerevisiae SEC20 gene encodes a membrane glycoprotein which is sorted by the HDEL retrieval system.Analysis of oxysterol binding protein homologue Kes1p function in regulation of Sec14p-dependent protein transport from the yeast Golgi complex.SAC1p is an integral membrane protein that influences the cellular requirement for phospholipid transfer protein function and inositol in yeast.The EH-domain-containing protein Pan1 is required for normal organization of the actin cytoskeleton in Saccharomyces cerevisiae.A synthetic lethal screen identifies SLK1, a novel protein kinase homolog implicated in yeast cell morphogenesis and cell growth.Molecular basis of cell integrity and morphogenesis in Saccharomyces cerevisiaeKes1p shares homology with human oxysterol binding protein and participates in a novel regulatory pathway for yeast Golgi-derived transport vesicle biogenesis.Direct involvement of phosphatidylinositol 4-phosphate in secretion in the yeast Saccharomyces cerevisiae.Identification and characterization of a sac domain-containing phosphoinositide 5-phosphataseThe HIV-1 vpr protein induces anoikis-resistance by modulating cell adhesion process and microfilament system assemblyIdentification and characterization of a synaptojanin 2 splice isoform predominantly expressed in nerve terminalsGenetic ablation of phosphatidylinositol transfer protein function in murine embryonic stem cellsFunctional characterization of a mammalian Sac1 and mutants exhibiting substrate-specific defects in phosphoinositide phosphatase activityPhospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defectsPhosphatidylinositol transfer proteins and instructive regulation of lipid kinase biology
P2860
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P2860
Mutations in the SAC1 gene suppress defects in yeast Golgi and yeast actin function
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
Mutations in the SAC1 gene suppress defects in yeast Golgi and yeast actin function
@ast
Mutations in the SAC1 gene suppress defects in yeast Golgi and yeast actin function
@en
type
label
Mutations in the SAC1 gene suppress defects in yeast Golgi and yeast actin function
@ast
Mutations in the SAC1 gene suppress defects in yeast Golgi and yeast actin function
@en
prefLabel
Mutations in the SAC1 gene suppress defects in yeast Golgi and yeast actin function
@ast
Mutations in the SAC1 gene suppress defects in yeast Golgi and yeast actin function
@en
P2093
P2860
P356
P1476
Mutations in the SAC1 gene suppress defects in yeast Golgi and yeast actin function
@en
P2093
Bankaitis VA
P2860
P304
P356
10.1083/JCB.109.6.2939
P407
P433
P577
1989-12-01T00:00:00Z