Role of peroxisome proliferator-activated receptor alpha in disease of pancreatic beta cells.
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Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasisTranscriptional regulation of lipid metabolism by fatty acids: a key determinant of pancreatic beta-cell functionRole of BAF60a/BAF60c in chromatin remodeling and hepatic lipid metabolismOverexpression of leptin receptors in pancreatic islets of Zucker diabetic fatty rats restores GLUT-2, glucokinase, and glucose-stimulated insulin secretionPPARdelta is a fatty acid sensor that enhances mitochondrial oxidation in insulin-secreting cells and protects against fatty acid-induced dysfunctionFenofibrate prevents and reduces body weight gain and adiposity in diet-induced obese rats.AMPK enhances the expression of pancreatic duodenal homeobox-1 via PPARalpha, but not PPARgamma, in rat insulinoma cell line INS-1Lipid metabolism and resistin gene expression in insulin-resistant Fischer 344 rats.Biochemical mechanism of lipid-induced impairment of glucose-stimulated insulin secretion and reversal with a malate analogue.Hypertriglyceridemia: a too long unfairly neglected major cardiovascular risk factor.Effects of free fatty acids on insulin secretion in obesity.ChREBP mediates glucose repression of peroxisome proliferator-activated receptor alpha expression in pancreatic beta-cells.Leptin and the adipocyte endocrine system.Expression and functional activity of PPARgamma in pancreatic beta cells.Alteration of mitochondrial function in adult rat offspring of malnourished dams.PPARs in the Control of Uncoupling Proteins Gene Expression.Expression of PPARalpha modifies fatty acid effects on insulin secretion in uncoupling protein-2 knockout mice.Triglyceride, nonesterified fatty acids, and prediabetic neuropathy: role for oxidative-nitrosative stress.Ablation of vimentin results in defective steroidogenesis.Targeted elimination of peroxisome proliferator-activated receptor gamma in beta cells leads to abnormalities in islet mass without compromising glucose homeostasis.Nutrigenomics, beta-cell function and type 2 diabetesWAT is a functional adipocyte?Lipotoxic heart disease in obese rats: implications for human obesity.Regulation of fatty acid homeostasis in cells: novel role of leptin.The renoprotective actions of peroxisome proliferator-activated receptors agonists in diabetes.Impact of PPARgamma overexpression and activation on pancreatic islet gene expression profile analyzed with oligonucleotide microarrays.The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes.Suppression effects of AICAR on insulin secretion involved in peroxisome proliferator-activated receptor gamma changes in INS-1 cells.Chronic palmitate exposure inhibits AMPKalpha and decreases glucose-stimulated insulin secretion from beta-cells: modulation by fenofibrate.Pomegranate flower improves cardiac lipid metabolism in a diabetic rat model: role of lowering circulating lipids.Repression of glucagon gene transcription by peroxisome proliferator-activated receptor gamma through inhibition of Pax6 transcriptional activity.Evaluation of the role of peroxisome-proliferator-activated receptor alpha in the regulation of cardiac pyruvate dehydrogenase kinase 4 protein expression in response to starvation, high-fat feeding and hyperthyroidism.The dual PPARalpha/gamma agonist, ragaglitazar, improves insulin sensitivity and metabolic profile equally with pioglitazone in diabetic and dietary obese ZDF rats.Long-term treatment with atrial natriuretic peptide inhibits ATP production and insulin secretion in rat pancreatic islets.Impact of plasmatic lipids in glycemic control and its influence in the cardiometabolic risk in morbidly obese subjects.The influence of the polymorphism in apolipoprotein B codon 2488 on insulin and lipid levels in a Danish twin population.Combination therapy with PPARgamma and PPARalpha agonists increases glucose-stimulated insulin secretion in db/db mice.Rosiglitazone prevents the impairment of human islet function induced by fatty acids: evidence for a role of PPARgamma2 in the modulation of insulin secretion.Non-esterified fatty acids are deleterious for human pancreatic islet function at physiological glucose concentration.Gene expression and adiposity are modified by soy protein in male Zucker diabetic fatty rats.
P2860
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P2860
Role of peroxisome proliferator-activated receptor alpha in disease of pancreatic beta cells.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Role of peroxisome proliferato ...... ease of pancreatic beta cells.
@ast
Role of peroxisome proliferato ...... ease of pancreatic beta cells.
@en
type
label
Role of peroxisome proliferato ...... ease of pancreatic beta cells.
@ast
Role of peroxisome proliferato ...... ease of pancreatic beta cells.
@en
prefLabel
Role of peroxisome proliferato ...... ease of pancreatic beta cells.
@ast
Role of peroxisome proliferato ...... ease of pancreatic beta cells.
@en
P2093
P2860
P356
P1476
Role of peroxisome proliferato ...... ease of pancreatic beta cells.
@en
P2093
C B Newgard
J L Milburn
M Shimabukuro
P2860
P304
P356
10.1073/PNAS.95.15.8898
P407
P577
1998-07-01T00:00:00Z