Lipotoxic heart disease in obese rats: implications for human obesity. - Wikidata - awgldk - TriplyDB

Lipotoxic heart disease in obese rats: implications for human obesity.

Lipotoxic heart disease in obese rats: implications for human obesity.

http://www.wikidata.org/entity/Q37117677

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Ectopic fat and insulin resistance: pathophysiology and effect of diet and lifestyle interventions Apolipoprotein O is mitochondrial and promotes lipotoxicity in heart A critical role for eukaryotic elongation factor 1A-1 in lipotoxic cell death Leptin therapy in insulin-deficient type I diabetes Saturated free fatty acids and apoptosis in microvascular mesangial cells: palmitate activates pro-apoptotic signaling involving caspase 9 and mitochondrial release of endonuclease G Glucose-stimulated insulin response in pregnant sheep following acute suppression of plasma non-esterified fatty acid concentrations Myocardial dysfunction in rheumatoid arthritis: epidemiology and pathogenesis PGC-1/Spargel Counteracts High-Fat-Diet-Induced Obesity and Cardiac Lipotoxicity Downstream of TOR and Brummer ATGL Lipase.Cardiac contractile dysfunction in insulin-resistant rats fed a high-fat diet is associated with elevated CD36-mediated fatty acid uptake and esterification Cell Death and Heart Failure in Obesity: Role of Uncoupling Proteins The Use of SGLT-2 Inhibitors in Type 2 Diabetes and Heart Failure Defects of the heart, eye, and megakaryocytes in peroxisome proliferator activator receptor-binding protein (PBP) null embryos implicate GATA family of transcription factors Leptin, troglitazone, and the expression of sterol regulatory element binding proteins in liver and pancreatic islets The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus Hearts from mice fed a non-obesogenic high-fat diet exhibit changes in their oxidative state, calcium and mitochondria in parallel with increased susceptibility to reperfusion injury Diabetic cardiomyopathy: signaling defects and therapeutic approaches Mice deficient in mitochondrial glycerol-3-phosphate acyltransferase-1 have diminished myocardial triacylglycerol accumulation during lipogenic diet and altered phospholipid fatty acid composition β-Lapachone ameliorates lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice Myocardial Structural and Biological Anomalies Induced by High Fat Diet in Psammomys obesus Gerbils Molecular role of GATA binding protein 4 (GATA-4) in hyperglycemia-induced reduction of cardiac contractility Distinct transcriptional regulation of long-chain acyl-CoA synthetase isoforms and cytosolic thioesterase 1 in the rodent heart by fatty acids and insulin Leptin activates cardiac fatty acid oxidation independent of changes in the AMP-activated protein kinase-acetyl-CoA carboxylase-malonyl-CoA axis Reduced heart size and increased myocardial fuel substrate oxidation in ACC2 mutant mice Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis Oxidative stress and diabetic complications Mangiferin modulation of metabolism and metabolic syndrome.Phospholipid homeostasis and lipotoxic cardiomyopathy: a matter of balance.A novel MitoTimer reporter gene for mitochondrial content, structure, stress, and damage in vivo.Excessive Weight and Obesity Are Associated to Intra-Ventricular Asynchrony: Pilot Study Obesity reduces left ventricular strains, torsion, and synchrony in mouse models: a cine displacement encoding with stimulated echoes (DENSE) cardiovascular magnetic resonance study.Bayesian parameter estimation for characterizing the cyclic variation of echocardiographic backscatter to assess the hearts of asymptomatic type 2 diabetes mellitus subjects.Quantitative analysis of the magnitude and time delay of cyclic variation of myocardial backscatter from asymptomatic type 2 diabetes mellitus subjects.Spontaneously beating cardiomyocytes derived from white mature adipocytes.(1)H-MR spectroscopy for analysis of cardiac lipid and creatine metabolism.Myocardial Metabolic Abnormality in a Primary Left Atrial Rhabdomyosarcoma: Localized 1H MR Spectroscopy.Quantification of Intramyocardial Metabolites by Proton Magnetic Resonance Spectroscopy.Myocardial triglyceride content at 3 T cardiovascular magnetic resonance and left ventricular systolic function: a cross-sectional study in patients hospitalized with acute heart failure.Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice.Different effects of palmitoyl-L-carnitine and palmitoyl-CoA on mitochondrial function in rat ventricular myocytes.

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P2860

Lipotoxic heart disease in obese rats: implications for human obesity.

http://www.wikidata.org/entity/Q37117677

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on February 2000

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vedecký článok

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vetenskaplig artikel

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vědecký článek

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name

Lipotoxic heart disease in obese rats: implications for human obesity.

@en

Lipotoxic heart disease in obese rats: implications for human obesity.

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Lipotoxic heart disease in obese rats: implications for human obesity.

@en

Lipotoxic heart disease in obese rats: implications for human obesity.

@nl

prefLabel

Lipotoxic heart disease in obese rats: implications for human obesity.

@en

Lipotoxic heart disease in obese rats: implications for human obesity.

@nl

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Proceedings of the National Academy of Sciences of the United States of America

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Lipotoxic heart disease in obese rats: implications for human obesity.

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A Karim

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D Baetens

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L Orci

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M Higa

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M Shimabukuro

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P Grayburn

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R H Unger

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Y T Zhou

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P2860

Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers

Retrograde protein translocation: ERADication of secretory proteins in health and disease.

Troglitazone prevents mitochondrial alterations, beta cell destruction, and diabetes in obese prediabetic rats.

Ceramide is involved in triggering of cardiomyocyte apoptosis induced by ischemia and reperfusion

Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships.

Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes.

Role of peroxisome proliferator-activated receptor alpha in disease of pancreatic beta cells.

Regulation of fatty acid homeostasis in cells: novel role of leptin.

Reversing adipocyte differentiation: implications for treatment of obesity

Role of nitric oxide in obesity-induced beta cell disease.

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1784-1789

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10.1073/PNAS.97.4.1784

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