A unique requirement for the leukotriene B4 receptor BLT1 for neutrophil recruitment in inflammatory arthritis. - Wikidata - awgldk - TriplyDB

A unique requirement for the leukotriene B4 receptor BLT1 for neutrophil recruitment in inflammatory arthritis.

A unique requirement for the leukotriene B4 receptor BLT1 for neutrophil recruitment in inflammatory arthritis.

http://www.wikidata.org/entity/Q36228601

about

K/BxN Serum-Transfer Arthritis as a Model for Human Inflammatory Arthritis The role of platelets in the recruitment of leukocytes during vascular disease IFN-λ resolves inflammation via suppression of neutrophil infiltration and IL-1β production.Rapid immunomagnetic negative enrichment of neutrophil granulocytes from murine bone marrow for functional studies in vitro and in vivo The LTB4-BLT1 axis mediates neutrophil infiltration and secondary injury in experimental spinal cord injury.Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7 Saposin C coupled lipid nanovesicles specifically target arthritic mouse joints for optical imaging of disease severity Neutrophils in a mouse model of autoantibody-mediated arthritis: critical producers of Fc receptor gamma, the receptor for C5a, and lymphocyte function-associated antigen 1 Synaptotagmin-mediated vesicle fusion regulates cell migration.Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo.Complement C5a Receptor is the Key Initiator of Neutrophil Adhesion Igniting Immune Complex-induced Arthritis.Human-specific epigenetic variation in the immunological Leukotriene B4 Receptor (LTB4R/BLT1) implicated in common inflammatory diseases Transcriptional regulation of bone and joint remodeling by NFAT LTB4 is a signal-relay molecule during neutrophil chemotaxis Macrophages and β-cells are responsible for CXCR2-mediated neutrophil infiltration of the pancreas during autoimmune diabetes The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitment Role of PI3Kdelta and PI3Kgamma in inflammatory arthritis and tissue localization of neutrophils.The tumor microenvironment shapes lineage, transcriptional, and functional diversity of infiltrating myeloid cells.Deficiency of CXCR2, but not other chemokine receptors, attenuates autoantibody-mediated arthritis in a murine model Vav/Phospholipase Cgamma2-mediated control of a neutrophil-dependent murine model of rheumatoid arthritis.Interleukin-33 primes mast cells for activation by IgG immune complexes A novel anti-inflammatory role for secretory phospholipase A2 in immune complex-mediated arthritis.Neutrophils are required for both the sensitization and elicitation phase of contact hypersensitivity Distinct cellular sources of hepoxilin A3 and leukotriene B4 are used to coordinate bacterial-induced neutrophil transepithelial migration.Macrophage immunoregulatory pathways in tuberculosis.Lipid-cytokine-chemokine cascade drives neutrophil recruitment in a murine model of inflammatory arthritis Real-time imaging of leukotriene B₄ mediated cell migration and BLT1 interactions with β-arrestin.The absence of the leukotriene B4 receptor BLT1 attenuates peripheral inflammation and spinal nociceptive processing following intraplantar formalin injury.Deletion of Syk in neutrophils prevents immune complex arthritis Platelets participate in synovitis via Cox-1-dependent synthesis of prostacyclin independently of microparticle generation.The chemokine system in innate immunity.Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A2-IIA 5-Lipoxygenase-deficient mice infected with Borrelia burgdorferi develop persistent arthritis.Clinical trial of a leucotriene B4 receptor antagonist, BIIL 284, in patients with rheumatoid arthritis.A 4-trifluoromethyl analogue of celecoxib inhibits arthritis by suppressing innate immune cell activation Characterisation of the Whole Blood mRNA Transcriptome in Holstein-Friesian and Jersey Calves in Response to Gradual Weaning.Dietary fish oil substitution alters the eicosanoid profile in ankle joints of mice during Lyme infection Ly6G ligation blocks recruitment of neutrophils via a β2-integrin-dependent mechanism Neutrophil-derived leukotriene B4 is required for inflammatory arthritis Mast cell deficiency in Kit(W-sh) mice does not impair antibody-mediated arthritis

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P2860

A unique requirement for the leukotriene B4 receptor BLT1 for neutrophil recruitment in inflammatory arthritis.

http://www.wikidata.org/entity/Q36228601

description

2006 nî lūn-bûn

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A unique requirement for the l ...... ent in inflammatory arthritis.

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A unique requirement for the l ...... ent in inflammatory arthritis.

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Andrew D Luster

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Andrew M Tager

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Edward Seung

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Nancy D Kim

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Richard C Chou

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P2860

A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis

Neutrophil granules and secretory vesicles in inflammation

Differential expression of leukotriene B4 receptor subtypes (BLT1 and BLT2) in human synovial tissues and synovial fluid leukocytes of patients with rheumatoid arthritis

Relationship between leukotriene B4 and immunological parameters in rheumatoid synovial fluids

Targeted disruption of the leukotriene B(4) receptor in mice reveals its role in inflammation and platelet-activating factor-induced anaphylaxis

BLTR mediates leukotriene B(4)-induced chemotaxis and adhesion and plays a dominant role in eosinophil accumulation in a murine model of peritonitis

Molecular and biological characterization of the murine leukotriene B4 receptor expressed on eosinophils

Mast cells: a cellular link between autoantibodies and inflammatory arthritis.

The role of leukotrienes in inflammation.

Leukotriene B4 plays a critical role in the progression of collagen-induced arthritis.

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