X-linked susceptibility to mycobacteria is caused by mutations in NEMO impairing CD40-dependent IL-12 production.
about
Enhanced binding of TBK1 by an optineurin mutant that causes a familial form of primary open angle glaucomaLys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activationSevere infectious diseases of childhood as monogenic inborn errors of immunityInnate Immune Defenses in Human Tuberculosis: An Overview of the Interactions between Mycobacterium tuberculosis and Innate Immune CellsMendelian susceptibility to mycobacterial disease: genetic, immunological, and clinical features of inborn errors of IFN-γ immunityLinear ubiquitination signals in adaptive immune responsesStructural Basis for Recognition of Diubiquitins by NEMO'"Why me, why now?" Using clinical immunology and epidemiology to explain who gets nontuberculous mycobacterial infectionSelective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunityA novel form of cell type-specific partial IFN-gammaR1 deficiency caused by a germ line mutation of the IFNGR1 initiation codon.Inhibition of NF-kappaB activation with designed ankyrin-repeat proteins targeting the ubiquitin-binding/oligomerization domain of NEMO.Nod-like receptors: cytosolic watchdogs for immunity against pathogens.Sexual inequality in tuberculosis.Deep dermatophytosis and inherited CARD9 deficiencyHuman TRAF3 adaptor molecule deficiency leads to impaired Toll-like receptor 3 response and susceptibility to herpes simplex encephalitis.Relating diseases by integrating gene associations and information flow through protein interaction networkBiallelic loss-of-function mutation in NIK causes a primary immunodeficiency with multifaceted aberrant lymphoid immunity.Molecular immunity to mycobacteria: knowledge from the mutation and phenotype spectrum analysis of Mendelian susceptibility to mycobacterial diseases.NF-κB Essential Modulator Deficiency Leading to Disseminated Cutaneous Atypical Mycobacteria.Germline CYBB mutations that selectively affect macrophages in kindreds with X-linked predisposition to tuberculous mycobacterial disease.Infectious diseases in patients with IRAK-4, MyD88, NEMO, or IκBα deficiency.NEMO is a key component of NF-κB- and IRF-3-dependent TLR3-mediated immunity to herpes simplex virus.Inherited and acquired immunodeficiencies underlying tuberculosis in childhood.New mechanism of X-linked anhidrotic ectodermal dysplasia with immunodeficiency: impairment of ubiquitin binding despite normal folding of NEMO protein.Human genetics of infectious diseases: a unified theoryInborn errors of anti-viral interferon immunity in humans.Genetic lessons learned from X-linked Mendelian susceptibility to mycobacterial diseases.Inborn errors of human JAKs and STATs.Mendelian susceptibility to mycobacterial disease in egyptian children.Interleukin-12 and tuberculosis: an old story revisitedToll-like receptor signaling in primary immune deficiencies.Haploinsufficiency at the human IFNGR2 locus contributes to mycobacterial disease.Recruitment of A20 by the C-terminal domain of NEMO suppresses NF-κB activation and autoinflammatory disease.A genetic perspective on granulomatous diseases with an emphasis on mycobacterial infections.ISG15: leading a double life as a secreted molecule.Complementation of a pathogenic IFNGR2 misfolding mutation with modifiers of N-glycosylation.Dominant-negative STAT1 SH2 domain mutations in unrelated patients with Mendelian susceptibility to mycobacterial diseaseSTAT2: A shape-shifting anti-viral super STATThe novel IFNGR1 mutation 774del4 produces a truncated form of interferon-gamma receptor 1 and has a dominant-negative effect on interferon-gamma signal transduction.A novel X-linked recessive form of Mendelian susceptibility to mycobaterial disease.
P2860
Q24318807-F4CEFF8C-B930-4C62-A1F9-0B5F09A7380AQ24641992-220F3F64-A829-4B05-92FC-78500215B90BQ26775891-F22623F1-F24F-47F0-BAF7-F0D0CD818CE8Q26799901-FD538312-D7BF-47AD-875A-9F96AFA7BCC4Q26862947-5EF712E3-3AC9-4329-B74D-D88C91A26F24Q27027872-2845EAA9-1A61-4BED-9D52-04EAC6E8F2B8Q27653619-CE8667E5-219F-4DD6-A588-34793B5B64B2Q28070339-35B6BD45-8FC6-4C7C-9AA8-8BFC333A6BAEQ28250405-EF63E368-ADC0-4B14-9F1C-FFF72A68CA0DQ30492620-1EF72905-3B42-4C9D-B3E1-D4AEBEC45EB1Q33296431-5D88E88A-0A4B-499A-BE6D-25414497411EQ33312855-CCA7CC67-44DA-4492-8F33-D7EFEF9C7ED2Q33520199-30F3413E-4C5B-4306-9FA5-366720C44296Q33855073-41C7DDE2-CD21-4D18-A1FA-DD52CF7E97AFQ34158815-A57D91BD-0271-4B84-94C5-5B69836ABCFEQ34434695-00D14960-0D72-41BB-B347-414BBCDA8F0BQ34677647-6945511C-7AF2-4F0D-BEBE-9ABE1594FE00Q34809934-43B8D01B-BEB4-4D8E-B885-F0BC48BE6E28Q34822113-1010774C-024D-48C4-8B88-C1917C8B5BE6Q34992223-96515E8C-2378-49D1-895F-2154B5AD8B8EQ35090141-EA3EEE57-DF5B-4368-9273-62ACF1A9FDE3Q35190204-EEBC48B8-5394-461C-83B6-C02241FC0584Q35510477-A7CCC558-CF33-4DB3-83DE-2829A7A9AFFAQ35652037-A4316CCA-1D98-4657-B615-8F7DCA65F3ACQ35752931-6D6777B2-587D-48A2-9B62-642E78217DCDQ35759651-D2C8DF47-BBF6-4D7E-AE82-9E166F0A66CFQ35860015-EE21481B-0737-4DA3-B085-8F07AC3B7C89Q35908479-3343FCF9-0E6E-486C-A45D-43C30AFAAB23Q36033806-93E88E16-9E9B-426B-A4CC-D5F343630C78Q36137298-FE32B6FA-A8A0-4F7B-B87A-D597C5635755Q36238886-51DAC69C-DAE8-4993-95B7-70F35F3A2FEDQ36560000-CD5F021A-7E3C-4F43-99D4-B369F1C55092Q36598807-DCF0E1D9-8515-4255-8272-EF53E11ED958Q36654943-3A5E210E-9814-4CB6-A8C6-FC89941EA21AQ36809721-5078B6CA-E60C-4FAC-A5E0-3F7115C7F4D1Q36851855-DA2E9700-ECF9-4058-8E7A-12B2662FEC39Q36891402-5F281F7E-33E4-4C54-A661-567E53D067EAQ36895430-215A4180-CF3C-452B-92B1-1E8772164CE4Q37004539-8C2A6F89-2CDB-4D9E-BA24-A6ADE0CA026AQ37004799-F95E997E-2D1F-469F-808D-791590047078
P2860
X-linked susceptibility to mycobacteria is caused by mutations in NEMO impairing CD40-dependent IL-12 production.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
X-linked susceptibility to myc ...... 40-dependent IL-12 production.
@ast
X-linked susceptibility to myc ...... 40-dependent IL-12 production.
@en
type
label
X-linked susceptibility to myc ...... 40-dependent IL-12 production.
@ast
X-linked susceptibility to myc ...... 40-dependent IL-12 production.
@en
prefLabel
X-linked susceptibility to myc ...... 40-dependent IL-12 production.
@ast
X-linked susceptibility to myc ...... 40-dependent IL-12 production.
@en
P2093
P2860
P50
P356
P1476
X-linked susceptibility to myc ...... 40-dependent IL-12 production.
@en
P2093
Alain Israël
Alessandro Plebani
Brigitte Senechal
Cheng-Lung Ku
Christine Bodemer
Claire Fieschi
David M Frucht
Dominique Gendrel
Emilie Vinolo
Fabrice Agou
P2860
P304
P356
10.1084/JEM.20060085
P407
P50
P577
2006-07-03T00:00:00Z