Importance of group X-secreted phospholipase A2 in allergen-induced airway inflammation and remodeling in a mouse asthma model.
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Group X secretory phospholipase A2 negatively regulates ABCA1 and ABCG1 expression and cholesterol efflux in macrophagesBlockade of human group X secreted phospholipase A2 (GX-sPLA2)-induced airway inflammation and hyperresponsiveness in a mouse asthma model by a selective GX-sPLA2 inhibitorGroup X phospholipase A2 is released during sperm acrosome reaction and controls fertility outcome in miceGroup III secreted phospholipase A2 regulates epididymal sperm maturation and fertility in mice.Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic interventionBaicalein reduces airway injury in allergen and IL-13 induced airway inflammationMast cell maturation is driven via a group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axisPhospholipase A2 in experimental allergic bronchitis: a lesson from mouse and rat modelsLack of group X secreted phospholipase A₂ increases survival following pandemic H1N1 influenza infection.Transglutaminase 2, a novel regulator of eicosanoid production in asthma revealed by genome-wide expression profiling of distinct asthma phenotypesNovel biomarkers for cardiovascular risk prediction.Group X secretory phospholipase A2 regulates the expression of steroidogenic acute regulatory protein (StAR) in mouse adrenal glandsInhibition of Wnt/beta-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis.The step further to understand the role of cytosolic phospholipase A2 alpha and group X secretory phospholipase A2 in allergic inflammation: pilot study.Highly specific and broadly potent inhibitors of mammalian secreted phospholipases A2Transglutaminase II/microRNA-218/-181a loop regulates positive feedback relationship between allergic inflammation and tumor metastasis.Group V secretory phospholipase A2 reveals its role in house dust mite-induced allergic pulmonary inflammation by regulation of dendritic cell function.Group X secretory phospholipase A(2) augments angiotensin II-induced inflammatory responses and abdominal aortic aneurysm formation in apoE-deficient mice.Eosinophil cysteinyl leukotriene synthesis mediated by exogenous secreted phospholipase A2 group X.Anti-inflammatory effects of the R2 peptide, an inhibitor of transglutaminase 2, in a mouse model of allergic asthma, induced by ovalbumin.A bifunctional role for group IIA secreted phospholipase A2 in human rheumatoid fibroblast-like synoviocyte arachidonic acid metabolismKey role of group v secreted phospholipase A2 in Th2 cytokine and dendritic cell-driven airway hyperresponsiveness and remodeling.Hair follicular expression and function of group X secreted phospholipase A2 in mouse skin.Physiological roles of group X-secreted phospholipase A2 in reproduction, gastrointestinal phospholipid digestion, and neuronal function.Production of vascular endothelial growth factors from human lung macrophages induced by group IIA and group X secreted phospholipases A2Relationship between levels of secreted phospholipase A₂ groups IIA and X in the airways and asthma severity.Integrated lipidomics in the secreted phospholipase A(2) biology.Group X secretory phospholipase A2 enhances TLR4 signaling in macrophagesLeukotrienes and airway inflammationEctopically expressed pro-group X secretory phospholipase A2 is proteolytically activated in mouse adrenal cells by furin-like proprotein convertases: implications for the regulation of adrenal steroidogenesisSecretory phospholipases A2 are secreted from ciliated cells and increase mucin and eicosanoid secretion from goblet cells.A new era of secreted phospholipase A₂New insights into pathogenesis of exercise-induced bronchoconstriction.The role of group IIF-secreted phospholipase A2 in epidermal homeostasis and hyperplasiaGroup IVA phospholipase A₂ optimizes ovulation and fertilization in rodents through induction of and metabolic coupling with prostaglandin endoperoxide synthase 2.Secreted phospholipase A2 group X overexpression in asthma and bronchial hyperresponsiveness.Endogenous secreted phospholipase A2 group X regulates cysteinyl leukotrienes synthesis by human eosinophils.Distinct expression pattern of the full set of secreted phospholipases A2 in human colorectal adenocarcinomas: sPLA2-III as a biomarker candidate.Elucidating molecular networks that either affect or respond to plasma cortisol concentration in target tissues of liver and muscleProgesterone-induced Acrosome Exocytosis Requires Sequential Involvement of Calcium-independent Phospholipase A2β (iPLA2β) and Group X Secreted Phospholipase A2 (sPLA2)
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P2860
Importance of group X-secreted phospholipase A2 in allergen-induced airway inflammation and remodeling in a mouse asthma model.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Importance of group X-secreted ...... eling in a mouse asthma model.
@ast
Importance of group X-secreted ...... eling in a mouse asthma model.
@en
type
label
Importance of group X-secreted ...... eling in a mouse asthma model.
@ast
Importance of group X-secreted ...... eling in a mouse asthma model.
@en
prefLabel
Importance of group X-secreted ...... eling in a mouse asthma model.
@ast
Importance of group X-secreted ...... eling in a mouse asthma model.
@en
P2093
P2860
P356
P1476
Importance of group X-secreted ...... eling in a mouse asthma model.
@en
P2093
Alan G Singer
Alexander Y Rudensky
Emil Y Chi
Gertrude K S Chiang
James G Bollinger
Luca Castelli
Timo Nevalainen
William R Henderson
Ying-tzang Tien
P2860
P304
P356
10.1084/JEM.20070029
P407
P577
2007-04-02T00:00:00Z