A myelin basic protein peptide is recognized by cytotoxic T cells in the context of four HLA-DR types associated with multiple sclerosis
about
Theiler's virus infection: a model for multiple sclerosisRedundancy in antigen-presenting function of the HLA-DR and -DQ molecules in the multiple sclerosis-associated HLA-DR2 haplotypeHLA DRB4 0101-restricted immunodominant T cell autoepitope of pyruvate dehydrogenase complex in primary biliary cirrhosis: evidence of molecular mimicry in human autoimmune diseasesAntigen Presentation, Autoantigens, and Immune Regulation in Multiple Sclerosis and Other Autoimmune DiseasesSolution NMR structure of an immunodominant epitope of myelin basic protein. Conformational dependence on environment of an intrinsically unstructured protein.Does a retrovirally encoded superantigen cause multiple sclerosis?HLA class II restriction of autoreactive T cell responses in pemphigus vulgaris: review of the literature and potential applications for the development of a specific immunotherapy.Fine specificity of the antibody response to myelin basic protein in the central nervous system in multiple sclerosis: the minimal B-cell epitope and a model of its features.T cell receptor V genes in multiple sclerosis: increased use of TCRAV8 and TCRBV5 in MBP-specific clones.Design and Synthesis of Non-Peptide Mimetics Mapping the Immunodominant Myelin Basic Protein (MBP83-96) Epitope to Function as T-Cell Receptor Antagonists.Binding of myelin basic protein peptides to human histocompatibility leukocyte antigen class II molecules and their recognition by T cells from multiple sclerosis patientsMyelin basic protein-specific T lymphocyte repertoire in multiple sclerosis. Complexity of the response and dominance of nested epitopes due to recruitment of multiple T cell clonesT helper cell recognition of muscle acetylcholine receptor in myasthenia gravis. Epitopes on the gamma and delta subunits.Construction of peptides encompassing multideterminant clusters of human immunodeficiency virus envelope to induce in vitro T cell responses in mice and humans of multiple MHC types.Structure and specificity of T cell receptors expressed by potentially pathogenic anti-DNA autoantibody-inducing T cells in human lupus.Homologies between T cell receptor junctional sequences unique to multiple sclerosis and T cells mediating experimental allergic encephalomyelitisGlatiramer acetate and nanny proteins restrict access of the multiple sclerosis autoantigen myelin basic protein to the 26S proteasomeIncreased frequencies of myelin oligodendrocyte glycoprotein/MHC class II-binding CD4 cells in patients with multiple sclerosis.Autoreactive T cells in multiple sclerosis.Antigen-specific tolerance as a therapy for experimental autoimmune encephalomyelitis.Autoimmune thyroiditis and targeted anti-T cell immunotherapy in man.Heterogeneity of T-cell receptor alpha-chain complementarity-determining region 3 in myelin basic protein-specific T cells increases with severity of multiple sclerosis.Ubiquitin-independent proteosomal degradation of myelin basic protein contributes to development of neurodegenerative autoimmunityMyasthenia gravis. CD4+ T epitopes on the embryonic gamma subunit of human muscle acetylcholine receptorFunctional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosisA synthetic peptide from the third hypervariable region of major histocompatibility complex class II beta chain as a vaccine for treatment of experimental autoimmune encephalomyelitisGranzyme A released upon stimulation of cytotoxic T lymphocytes activates the thrombin receptor on neuronal cells and astrocytes.Encephalitogenic potential of myelin basic protein-specific T cells isolated from normal rhesus macaquesCDR3 sequence motifs shared by oligoclonal rheumatoid arthritis synovial T cells. Evidence for an antigen-driven response.Melanocyte antigen triggers autoimmunity in human psoriasis.Autoimmune concepts of multiple sclerosis as a basis for selective immunotherapy: from pipe dreams to (therapeutic) pipelines.Myelin basic protein-specific TCR/HLA-DRB5*01:01 transgenic mice support the etiologic role of DRB5*01:01 in multiple sclerosis.Detection of human T lymphotrophic virus type I (HTLV-I) proviral DNA and analysis of T cell receptor V beta CDR3 sequences in spinal cord lesions of HTLV-I-associated myelopathy/tropical spastic paraparesis.Identification of high potency microbial and self ligands for a human autoreactive class II-restricted T cell clone.A role for CD4+ T-cell subsets producing a selective pattern of lymphokines in the pathogenesis of human chronic inflammatory and allergic diseases.Complementary mutations in an antigenic peptide allow for crossreactivity of autoreactive T-cell clonesExpansion of a recurrent V beta 5.3+ T-cell population in newly diagnosed and untreated HLA-DR2 multiple sclerosis patientsNaturally presented peptides on major histocompatibility complex I and II molecules eluted from central nervous system of multiple sclerosis patients.Immunodominance of a low-affinity major histocompatibility complex-binding myelin basic protein epitope (residues 111-129) in HLA-DR4 (B1*0401) subjects is associated with a restricted T cell receptor repertoire.Identification and precursor frequency analysis of a common T cell epitope motif in mitochondrial autoantigens in primary biliary cirrhosis.
P2860
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P2860
A myelin basic protein peptide is recognized by cytotoxic T cells in the context of four HLA-DR types associated with multiple sclerosis
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
A myelin basic protein peptide ...... ciated with multiple sclerosis
@ast
A myelin basic protein peptide ...... ciated with multiple sclerosis
@en
type
label
A myelin basic protein peptide ...... ciated with multiple sclerosis
@ast
A myelin basic protein peptide ...... ciated with multiple sclerosis
@en
prefLabel
A myelin basic protein peptide ...... ciated with multiple sclerosis
@ast
A myelin basic protein peptide ...... ciated with multiple sclerosis
@en
P2093
P2860
P356
P1476
A myelin basic protein peptide ...... ciated with multiple sclerosis
@en
P2093
Brostoff S
Flerlage M
Jaraquemada D
McFarland HF
McFarlin DE
P2860
P356
10.1084/JEM.173.1.19
P407
P577
1991-01-01T00:00:00Z