Distinct effects of two CD44 isoforms on tumor growth in vivo.
about
LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronanCD44 cell adhesion moleculesCell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesisCD44 isoforms containing exon V3 are responsible for the presentation of heparin-binding growth factorIdentification of hyaluronic acid binding sites in the extracellular domain of CD44Molecular isoforms of murine CD44 and evidence that the membrane proximal domain is not critical for hyaluronate recognitionA splice variant of CD44 expressed in the apical ectodermal ridge presents fibroblast growth factors to limb mesenchyme and is required for limb outgrowthAmine-modified hyaluronic acid-functionalized porous silicon nanoparticles for targeting breast cancer tumors.Role of CD44 and its v7 isoform in staphylococcal enterotoxin B-induced toxic shock: CD44 deficiency on hepatic mononuclear cells leads to reduced activation-induced apoptosis that results in increased liver damage.The cellular and molecular basis of prostate cancer.Prognostic significance of CD44 expression in adenocarcinoma of the lung.Stromal hyaluronan interaction with epithelial CD44 variants promotes prostate cancer invasiveness by augmenting expression and function of hepatocyte growth factor and androgen receptorCoupling of osteopontin and its cell surface receptor CD44 to the cell survival response elicited by interleukin-3 or granulocyte-macrophage colony-stimulating factor.Osteoclasts and giant cells: macrophage-macrophage fusion mechanism.Spatio-temporal patterns of pancreatic cancer cells expressing CD44 isoforms on supported membranes displaying hyaluronic acid oligomers arrays.CD44 anchors the assembly of matrilysin/MMP-7 with heparin-binding epidermal growth factor precursor and ErbB4 and regulates female reproductive organ remodelingLocalization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion.Expression of CD44 in human neoplastic and normal hyaline cartilage.Hyaluronic acid-based nanocarriers for intracellular targeting: interfacial interactions with proteins in cancer.Alternatively spliced variants of the cell adhesion molecule CD44 and tumour progression in colorectal cancer.The interaction of versican with its binding partners.The in vivo cytotoxic activity of CD8+ T cell clones correlates with their levels of expression of adhesion moleculesRegulated expression of exon v6 containing isoforms of CD44 in man: downregulation during malignant transformation of tumors of squamocellular originThe cytoplasmic tail of CD44 is required for basolateral localization in epithelial MDCK cells but does not mediate association with the detergent-insoluble cytoskeleton of fibroblasts.Glycosylation of CD44 is implicated in CD44-mediated cell adhesion to hyaluronan.Assembly of pericellular matrices by COS-7 cells transfected with CD44 lymphocyte-homing receptor genesCD44 occupancy prevents macrophage multinucleation.Activated human lymphocytes and aggressive non-Hodgkin's lymphomas express a homologue of the rat metastasis-associated variant of CD44CD44 is necessary for optimal contact allergic responses but is not required for normal leukocyte extravasation.Interaction between CD44 and hyaluronate is directly implicated in the regulation of tumor development.Induction of apoptosis of metastatic mammary carcinoma cells in vivo by disruption of tumor cell surface CD44 functionIntegrin αvβ3 and CD44 pathways in metastatic prostate cancer cells support osteoclastogenesis via a Runx2/Smad 5/receptor activator of NF-κB ligand signaling axis.CD44H regulates tumor cell migration on hyaluronate-coated substrateExpression of CD44 by rhabdomyosarcoma: a new prognostic marker?Overexpressed human CD44s promotes lung colonization during micrometastasis of murine fibrosarcoma cells: facilitated retention in the lung vasculatureThe role of alternative splicing of the adhesion molecule, CD44, in lymphoid malignancyCD44-related chondroitin sulfate proteoglycan, a cell surface receptor implicated with tumor cell invasion, mediates endothelial cell migration on fibrinogen and invasion into a fibrin matrix.Acute lung injury fibroblast migration and invasion of a fibrin matrix is mediated by CD44.TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24- cancer cells.CD44 binds a chondroitin sulfate proteoglycan, aggrecan.
P2860
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P2860
Distinct effects of two CD44 isoforms on tumor growth in vivo.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Distinct effects of two CD44 isoforms on tumor growth in vivo.
@ast
Distinct effects of two CD44 isoforms on tumor growth in vivo.
@en
type
label
Distinct effects of two CD44 isoforms on tumor growth in vivo.
@ast
Distinct effects of two CD44 isoforms on tumor growth in vivo.
@en
prefLabel
Distinct effects of two CD44 isoforms on tumor growth in vivo.
@ast
Distinct effects of two CD44 isoforms on tumor growth in vivo.
@en
P2093
P2860
P356
P1476
Distinct effects of two CD44 isoforms on tumor growth in vivo.
@en
P2093
P2860
P304
P356
10.1084/JEM.174.4.859
P407
P577
1991-10-01T00:00:00Z